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Article
Open AccessIntegrating apaQTL and eQTL analysis identifies a potential causal variant associated with lung adenocarcinoma risk in the Chinese population
Alternative polyadenylation (APA) plays a crucial role in cancer biology. Here, we used data from the 3′aQTL-atlas, GTEx, and the China Nan**g Lung Cancer GWAS database to explore the association between apaQ...
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Article
Temperature modification of air pollutants and their synergistic effects on respiratory diseases in a semi-arid city in Northwest China
Air pollutants and temperature are significant threats to public health, and the complex linkages between the environmental factors and their interactions harm respiratory diseases. This study is aimed to anal...
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Article
Diterpene Coronarin Attenuates Lipopolysaccharide-Induced Acute Lung Injury in Both In Vivo and In Vitro Models
Acute lung injury (ALI) is a clinical condition occurs due to severe systemic inflammatory response for clinical stimulus like pneumonia, sepsis, trauma, aspiration, inhalation of toxic gases, and pancreatitis...
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Article
Open AccessCharacterization of air pollution and associated health risks in Gansu Province, China from 2015 to 2022
Air pollution poses a major threat to both the environment and public health. The air quality index (AQI), aggregate AQI, new health risk–based air quality index (NHAQI), and NHAQI-WHO were employed to quantit...
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Article
Comparing collagenase and silver sulfadiazine in deep second-degree burn treatment
The indications for collagenase ointment (CO) and its efficacy are not clearly established in the treatment of second-degree burn wounds. To evaluate the efficacy of CO versus silver sulfadiazine ointment (SSD...
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Article
Open AccessAdoption of the cardiopulmonary exercise test in the exercise ability and cardiopulmonary function rehabilitation of coronary artery disease (CAD) patients
This study aimed to explore the application of cardiopulmonary exercise testing in coronary artery disease (CAD) patients, evaluate its impact on exercise ability and cardiopulmonary function in patients with ...
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Article
Open AccessConstruction and application of procedural pathways combined with information management in nursing staff skills training system
To explore the application effect of procedural pathways combined with information management in the construction of nursing staff skills training system.
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Article
Open AccessUSP47 deficiency in mice modulates tumor infiltrating immune cells and enhances antitumor immune responses in prostate cancer
This study investigates the role of USP47, a deubiquitinating enzyme, in the tumor microenvironment and its impact on antitumor immune responses. Analysis of TCGA database revealed distinct expression patterns...
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Article
Open AccessGenomic characterization reveals distinct mutational landscapes and therapeutic implications between different molecular subtypes of triple-negative breast cancer
Triple-negative breast cancer (TNBC) has high heterogeneity, poor prognosis, and limited treatment success. Recently, an immunohistochemistry-based surrogate classification for the “Fudan University Shanghai C...
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Article
Open AccessIntegrated analysis of the DNA methylome and RNA transcriptome during the development of skeletal muscle in Duroc pigs
Skeletal muscle development plays a crucial role in yield and quality of pork; however, this process is influenced by various factors. In this study, we employed whole-genome bisulfite sequencing (WGBS) and tr...
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Article
Evaluation of temperature modifying effect of PM2.5 on respiratory mortality in high latitude monsoon area
Particulate matter (PM) has been demonstrated to be a significant risk for the onset of respiratory diseases worldwide. We used a generalized additive model (GAM) to evaluate the effect of PM2.5 on respiratory mo...
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Article
Open AccessEvaluating the mosquito vector range for two orthobunyaviruses: Oya virus and Ebinur Lake virus
Mosquito-borne viruses cause various infectious diseases in humans and animals. Oya virus (OYAV) and Ebinur Lake virus (EBIV), belonging to the genus Orthobunyavirus within the family Peribunyaviridae, are recogn...
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Article
Role of Hexagonal Mesoporous Silica (HMS) in Enhancing the Stability of Ge Catalyst
In this study, the ordered mesoporous structure (HMS) was used as the carrier for Ge catalyst to enhance the catalyst stability. The results show that the large specific surface area of HMS material can effici...
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Article
Exfoliation Corrosion of As-Extruded Mg–1Li–1Ca: the Influence of the Superficial Layer
Exfoliation corrosion (EFC) has rarely been reported for wrought magnesium alloys. Enhanced EFC of the as-extruded Mg–1Li–1Ca alloy was observed after the removal of outermost fine-grained skins. The microstru...
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Article
Open AccessPerceptions of Chinese women with a history of gestational diabetes regarding health behaviors and related factors: a directed qualitative content analysis
Gestational diabetes mellitus (GDM) is one of the most common metabolic disorders during pregnancy and is associated with adverse outcomes in both mothers and their children. After delivery, women who experien...
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Article
Prevalence and influencing factors of patient delay in stroke patients: a systematic review and meta-analysis
Purpose: Determine the prevalence and influencing factors of patient delay in stroke patients and explore variation in prevalence by country and delayed time. Methods: PubMed, The Cochrane Library, Embase, Web...
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Article
The effect of indoor air filtration on biomarkers of inflammation and oxidative stress: a review and meta-analysis of randomized controlled trials
Improvement of indoor air quality is beneficial for human health. However, previous studies have not reached consistent conclusions regarding the effects of indoor air filtration on inflammation and oxidative ...
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Article
Reverse electrodialysis heat engine with helium-gap diffusion distillation: Energy efficiency analysis
The depletion of energy resources poses a significant threat to the development of human society. Specifically, a considerable amount of low-grade heat (LGH), typically below 100 °C, is currently being wasted....
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Article
Daratumumab and venetoclax combined with CAGE for late R/R T-ALL/LBL patients: Single-arm, open-label, phase I study
The prognosis of patients diagnosed with relapsed or refractory (R/R) T-lymphoblastic leukemia/lymphoma (T-ALL/LBL) has consistently been unsatisfactory, with limited treatment options. As reports, the CAG reg...
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Article
Open AccessInter- and trans-generational impacts of real-world PM2.5 exposure on male-specific primary hypogonadism
Exposure to PM2.5, a harmful type of air pollution, has been associated with compromised male reproductive health; however, it remains unclear whether such exposure can elicit transgenerational effects on male fe...
