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Life Sciences
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Article
Novel recycling strategy for distillers’ grains waste: prolonged biochar aging promotes cadmium immobilization and lettuce growth by regulating soil nutrient availability and bacterial composition
Converting distillers’ grains (DGs) into biochar (BC) is sustainable option for waste-recycling, but how different aging times and application rates DG-derived BC (DG-BC) influenced lettuce growth and cadmium ...
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Open AccessSystematic comparison of sequencing-based spatial transcriptomic methods
Recent developments of sequencing-based spatial transcriptomics (sST) have catalyzed important advancements by facilitating transcriptome-scale spatial gene expression measurement. Despite this progress, effor...
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Divergent responses to climatic conditions in radial growth of Abies fargesii along elevation at the eastern edge of the Tibetan Plateau
A gradual change exists in the altitudinal response of earlywood growth of Abies fargesii to hydrothermal conditions, with temperature being the main climatic factor controlling its latewood growth.
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Open AccessGenetic Prediction of Osteoporosis by Anti-Müllerian Hormone Levels and Reproductive Factors in Women: A Mendelian Randomization Study
Previous observational studies have suggested that anti-Müllerian hormone (AMH) and reproductive factors are linked to reduced bone mineral density (BMD) and an increased risk of osteoporosis (OP) in women. Ho...
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Open AccessVirtual reality-empowered deep-learning analysis of brain cells
Automated detection of specific cells in three-dimensional datasets such as whole-brain light-sheet image stacks is challenging. Here, we present DELiVR, a virtual reality-trained deep-learning pipeline for de...
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Evaluating the effect of manual hoeing and chemical weed management practices on the productivity and profitability of dry bean (Phaseolus vulgaris L.) in the south-eastern zone of the DR Congo
The proliferation of weeds in agricultural fields competes directly with crops for essential resources such as, leading to reduced crop yields and economic profitability. The objective of this study was to eva...
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Open AccessBacterial c-di-GMP triggers metamorphosis of mussel larvae through a STING receptor
Bacteria induced metamorphosis observed in nearly all marine invertebrates. However, the mechanism of bacteria regulating the larvae-juvenile metamorphosis remains unknown. Here, we test the hypothesis that c-...
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Article
Exploring the Correlation Between Varied Serum Iodine Nutritional Levels and Anti-Thyroglobulin Antibodies
Iodine deficiency results in elevated thyroglobulin (Tg) concentrations, with high iodine Tg being more immunogenic than low iodine Tg. The study investigated the correlation between serum iodine concentration...
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Comparative Bioactive Constituents, Radical Scavenging and Antidiabetic Properties of Fresh, Boiled and Air-Dried Momordica charantia Leaves
Herbal processing methods are important scientific techniques through which purity, herbal quality and therapeutic properties, including enhancement of effectiveness or reduction of plant toxicity, are assured...
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Evaluation of Anxiolytic Potential of Extract and Fractions of Vigna unguiculata spp dekindtiana in Mice
Anxiety disorder is mental disease that is characterised by feeling of worry or fear that interferes with daily activity. The folkloric use of Vigna unguiculata spp dekindtiana has been reported in the management...
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Nutritional, elemental, antioxidant and inhibitory potential of three tropical leafy vegetables against α-amylase and α-glucosidase
Leafy vegetables are prominent component of nutrition serving as prominent sources of vitamins, minerals and protein. They offer protection against chronic ailments. In this study, nutritional, elemental, and ...
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Open AccessThe COP9 signalosome stabilized MALT1 promotes Non-Small Cell Lung Cancer progression through activation of NF-κB pathway
MALT1 has been implicated as an upstream regulator of NF-κB signaling in immune cells and tumors. This study determined the regulatory mechanisms and biological functions of MALT1 in non-small cell lung cancer...
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Article
Germplasm collections and morphological studies of Andropogon gayanus–Andropogon tectorum complex in southwestern Nigeria
Morphological studies were carried out on collections of the Andropogon gayanus–Andropogon tectorum complex from Southwestern Nigeria to provide full characterization of accessions of the two species and elucidat...
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Toxicological assessments of aqueous extract of UV-C irradiated Bacopa floribunda leaves in healthy male albino rat
Consuming medicinal plants for the presumed health benefits have been a common practice since early civilization and study is ongoing in improving the activity of the active constituents as well as their toxic...
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Estimating rainfed groundnut’s leaf area index using Sentinel-2 based on Machine Learning Regression Algorithms and Empirical Models
The leaf area index (LAI), a crucial biophysical indicator, is used to assess and monitor crop growth for effective agricultural management. This study assessed the LAI at the seedling stage after conducting a...
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Article
SUB1 promotes colorectal cancer metastasis by activating NF-κB signaling via UBR5-mediated ubiquitination of UBXN1
Metastasis accounts for the major cause of colorectal cancer (CRC) related mortality due to the lack of effective treatments. In this study, we integrated the single-cell RNA-seq (scRNA-seq) and bulk RNA-seq d...
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Application and Comparison of Different Regression Models in Iodine Balance Experiment on Women of Childbearing Age and Pregnant Women
The iodine balance experiment is a traditional approach to evaluate the physiological requirement for iodine, while the simple linear regression model (SLM) and the mixed effects model (MEM) are two primary me...
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Open AccessGenome-wide cross-disease analyses highlight causality and shared biological pathways of type 2 diabetes with gastrointestinal disorders
Studies suggest links between diabetes and gastrointestinal (GI) traits; however, their underlying biological mechanisms remain unclear. Here, we comprehensively assess the genetic relationship between type 2 ...
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Expression and function analyses of the MIKCC-type MADS-box genes in Akebia trifoliata (Lardizabalaceae) flower development
The evolutionary origin and diversification of flowers in angiosperms remain one of the great unsolved mysteries in plants, while the molecular genetics of floral organ development are the crucial aspect of th...
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Synergistic changes in AM fungi and soil abiotic properties in rhizosphere soils of invasive Solidago canadensis may confer its stronger dominance in communities
Arbuscular mycorrhizal fungi (AMF) promote uptake of nutrients by plants; inversely, soil abiotic properties determine relationships between AMF and hosts. Although multiple hypotheses have suggested the impor...
