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203 Result(s)
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Article
Open AccessFollow-up of breast cancer in primary care vs specialist care: results of an economic evaluation
A randomized controlled trial (RCT) comparing primary-care-centred follow-up of breast cancer patients with the current standard practice of specialist-centred follow-up showed no increase in delay in diagnosi...
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Open AccessInadequate Knowledge About Sexually Transmitted Diseases[STDS] And Risky Sexual Behaviour: The Risk Factors for Wild Spread Of STDS Among Youth in Develo** Countries
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Molecular cloning and characterization of cDNA encoding a novel cytosolic glutathione transferase from Clonorchis sinensis
Glutathione transferases (GSTs) are a group of multifunction isoenzymes coded by many genes. A cDNA encoding a novel cytosolic GST enzyme was cloned from a Clonorchis sinensis (Cs) adult worm cDNA library by larg...
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Clonorchis sinensis: molecular cloning and functional expression of a novel cytosolic glutathione transferase
Glutathione transferases (GSTs) represent a large family of enzymes. In the high throughput sequencing of the cDNA library constructed from the adult stage of Clonorchis sinensis (Cs), we isolate another cDNA clo...
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Open AccessPerceptions of doctors to adverse drug reaction reporting in a teaching hospital in Lagos, Nigeria
Spontaneous adverse drug reaction (ADR) reporting is the cornerstone of pharmacovigilance. ADR reporting with Yellow Cards has tremendously improved pharmacovigilance of drugs in many developed countries and i...
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Open AccessMaturation of social attribution skills in typically develo** children: an investigation using the social attribution task
The assessment of social attribution skills in children can potentially identify and quantify developmental difficulties related to autism spectrum disorders and related conditions. However, relatively little ...
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Cloning and Characterization of Novel Isoforms of the BOULE Gene in Bats
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Open AccessA Longitudinal, Integrated, Clinical, Histological and mRNA Profiling Study of Resistance Exercise in Myositis
Polymyositis and dermatomyositis are orphan, chronic skeletal muscle disorders characterized by weakness, infiltrations by mononuclear inflammatory cells, and fibrosis. Until recently, patients were advised to...
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Open AccessImmunohistochemical localization of mu opioid receptor in the marginal division with comparison to patches in the neostriatum of the rat brain
Mu opioid receptor (MOR), which plays key roles in analgesia and also has effects on learning and memory, was reported to distribute abundantly in the patches of the neostriatum. The marginal division (MrD) of...
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Open AccessEscape is a more common mechanism than avidity reduction for evasion of CD8+ T cell responses in primary human immunodeficiency virus type 1 infection
CD8+ T cells play an important role in control of viral replication during acute and early human immunodeficiency virus type 1 (HIV-1) infection, contributing to containment of the acute viral burst and establ...
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Open AccessHepatitis B Core IgM antibody (anti-HBcIgM) among hepatitis B Surface antigen (HBsAg) negative blood donors in Nigeria
Transfusion associated Hepatitis B virus (TAHBV) continues to be a major problem despite mandatory screening for Hepatitis B surface Antigen (HBsAg). Presence of HBsAg is the common method for detecting hepati...
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Open AccessHypochlorite-induced oxidative stress elevates the capability of HDL in promoting breast cancer metastasis
Previous studies suggest that oxidative stress plays an important role in the development of breast cancer. There is a significant inverse relationship between HDL and the risk and mortality of breast cancer. ...
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Open AccessPrevalence of ulcer forming STIs among HIV-positive women clinic attendees in two Nigerian hospitals
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Open AccessPolyclonal HER2-specific antibodies induced by vaccination mediate receptor internalization and degradation in tumor cells
Sustained HER2 signaling at the cell surface is an oncogenic mechanism in a significant proportion of breast cancers. While clinically effective therapies targeting HER2 such as mAbs and tyrosine kinase inhibi...
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Open AccessAltered spontaneous activity in young chronic cigarette smokers revealed by regional homogeneity
Few studies have been previously published about the resting state brain activity in young chronic smokers, although many previous fMRI studies have shown that the task-related activity pattern is altered in c...
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Open AccessCharacterization of monoclonal antibodies against waterfowl parvoviruses VP3 protein
The VP3 protein of goose parvovirus (GPV) or Muscovy duck parvovirus (MDPV), a major structural protein, can induce neutralizing antibodies in geese and ducks, but monoclonal antibodies (MAbs) against VP3 prot...
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Open AccessThe clinical significance of Psoriasin for non-small cell lung cancer patients and its biological impact on lung cancer cell functions
Psoriasin (S100A7) is a member of the S100 gene family. Alteration of Psoriasin expression has previously been reported to play an important role in cancer aggressive behaviour. The current study sought to inv...
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Open AccessHighly conserved antigenic epitope regions of hemagglutinin and neuraminidase genes between 2009 H1N1 and seasonal H1N1 influenza: vaccine considerations
An immunoinformatics study was conducted to determine the highly conserved antigenic epitope regions of hemagglutinin (HA) and neuraminidase (NA) genes in the humoral immunity and CD4+ and CD8+ T cellular immu...
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Open AccessComparative analysis of the alveolar macrophage proteome in ALI/ARDS patients between the exudative phase and recovery phase
Despite decades of extensive studies, the morbidity and mortality for acute lung injury/acute respiratory distress syndrome (ALI/ARDS) remained high. Particularly, biomarkers essential for its early diagnosis ...
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Open AccessFOXO/TXNIP pathway is involved in the suppression of hepatocellular carcinoma growth by glutamate antagonist MK-801
Accumulating evidence has suggested the importance of glutamate signaling in cancer growth, yet the signaling pathway has not been fully elucidated. N-methyl-D-aspartic acid (NMDA) receptor activates intracell...