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Clinicopathologic analysis on 121 cases of nasal and nasopharyngeal lymphoma (NPL)
One handred twenty- one cases of nasal and nasopharyngeal lymphoma were analyzed in this paper. These cases were divided macroscopically into 4 main types including giant mass type, nodular type, thickbulgy ty...
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Article
Non-thoracotomy esophagectomy for carcinoma of the esophagus and cardia
Objective: To try to use Non-Thoracotomy Esophagectomy (NTE) for patient with carcinoma of esophagus and cardia avoiding thoracotomy, and by utilizing a cervical esophagogastric anastomosis in order to reduce ...
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Article
The examination of an EBV-DNase gene fragment in the paraffin-embedded NPC, precancerous and from high-risk population nasopharyngeal tissues
Objective: To examine if the EB virus appears in nasopharyngeal epithelial cells in the course of tumorigenesis in nasopharyngeal carcinoma (NPC). Methods: Based on the annual investigation of Sihui County, a ...
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Article
Clinical analysis of 57 patients with ovarian dysgerminoma
Ovarian dysgerminoma is an uncommon ovarian malignancy, Its clinicai features are special and there are many factors affecting its prognosis. If treated properly, the patient can be cured. Otherwise it may end...
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Article
A study of molecular resection margins for esophageal squamous cell carcinoma using large pathologic sections
OBJECTIVE It has been shown that application of molecular biological techniques to surgical margins of some cancers could predict risk of local recurrence. However, the optimal length of surgical...
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Article
Open AccessThe comparison of perioperative outcomes of robot-assisted and open partial nephrectomy: a systematic review and meta-analysis
Robot-assisted partial nephrectomy (RAPN) has been widely used worldwide, to determine whether RAPN is a safe and effective alternative to open partial nephrectomy (OPN) via the comparison of RANP and OPN.
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Article
Molecular profiling of tumors of the brainstem by sequencing of CSF-derived circulating tumor DNA
Brainstem gliomas are molecularly heterogeneous diseases, many of which are difficult to safely surgically resect and have limited treatment options due to their eloquent location. These constraints pose chall...
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Article
Open AccessTriglyceride-glucose index trajectory and arterial stiffness: results from Hanzhong Adolescent Hypertension Cohort Study
The triglyceride-glucose index (TyG index) has emerged as a reliable surrogate marker of insulin resistance associated with arterial stiffness. However, most studies were based on a cross-sectional design, and...
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Article
Robotic parenchymal-sparing pancreatectomy and pancreas-sparing duodenectomy avoid pancreaticoduodenectomy for benign and low-grade malignant tumours
Parenchymal-sparing pancreatectomy (PSP) or pancreas-sparing duodenectomy (PSD) is an alternative method for patients with benign or low-grade malignant tumours at the pancreatic head or duodenum. It avoids tr...
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Article
Src inhibitor dasatinib sensitized gastric cancer cells to cisplatin
Gastric cancer (GC) is characterized by high incidence and mortality, and lacks effective treatment. Surgery, combined with chemo- and radiation therapy, represents the cornerstones of GC treatment. Although p...
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Article
11C-methionine PET imaging characteristics in children with diffuse intrinsic pontine gliomas and relationship to survival and H3 K27M mutation status
This study aimed to describe 11C-methionine (11C-MET) PET imaging characteristics in patients with paediatric diffuse intrinsic pontine glioma (DIPG) and correlate them with survival and H3 K27M mutation status.
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Article
A multimodal imaging-based classification for pediatric diffuse intrinsic pontine gliomas
Pediatric diffuse intrinsic pontine glioma (DIPG) is a radiologically heterogeneous disease entity, here we aim to establish a multimodal imaging-based radiological classification and evaluate the outcome of d...
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Article
Open AccessIdentification of TRPM2 as a prognostic factor correlated with immune infiltration in ovarian cancer
Ovarian cancer (OC) is one of the most common gynecologic malignant cancers with the current survival rate remaining low. TRPM2 has been reported as a survival predictor in various cancers but not in OC. The a...
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Article
Open AccessMUC16 stimulates neutrophils to an inflammatory and immunosuppressive phenotype in ovarian cancer
MUC16 (CA125) is a commonly used tumor marker for ovarian cancer screening and reported to be an immunosuppressive factor by acting on the sialic acid-binding immunoglobulin-like lectin-9 (Siglec-9) on the sur...
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Article
Open AccessIL-2-free tumor-infiltrating lymphocyte therapy with PD-1 blockade demonstrates potent efficacy in advanced gynecologic cancer
Tumor-infiltrating lymphocyte (TIL) therapy has been restricted by intensive lymphodepletion and high-dose intravenous interleukin-2 (IL-2) administration. To address these limitations, we conducted preclinica...
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Article
Open AccessCausal associations between gut microbiota and chronic prostatitis/chronic pelvic pain syndrome: a two-sample Mendelian randomization study
Recent researches have increasingly indicated a strong correlation between the gut microbiota and chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS). Nevertheless, the impact of gut microbiota on CP/CP...