17 Result(s)
within
English
Science, Humanities and Social Sciences, multidisciplinary
**uJun Feng
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Article
Open AccessBiochemical and structural characterization of the BioZ enzyme engaged in bacterial biotin synthesis pathway
Biotin is an essential micro-nutrient across the three domains of life. The paradigm earlier step of biotin synthesis denotes “BioC-BioH” pathway in Escherichia coli. Here we report that BioZ bypasses the canonic...
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Article
Open AccessReconfigurable structured light generation in a multicore fibre amplifier
Structured light, with spatially varying phase or polarization distributions, has given rise to many novel applications in fields ranging from optical communication to laser-based material processing. However ...
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Article
Open AccessInteraction variability shapes succession of synthetic microbial ecosystems
Cellular interactions are a major driver for the assembly and functioning of microbial communities. Their strengths are shown to be highly variable in nature; however, it is unclear how such variations regulat...
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Article
Open AccessDiscrimination of CRISPR/Cas9-induced mutants of rice seeds using near-infrared hyperspectral imaging
Identifying individuals with target mutant phenotypes is a significant procedure in mutant exploitation for implementing genome editing technology in a crop breeding programme. In the present study, a rapid an...
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Article
Open AccessGenome characterization of two bile-isolated Vibrio fluvialis strains: an insight into pathogenicity and bile salt adaption
Vibrio fluvialis is recognized as an emerging pathogen. However, not much is known about the mechanism of its pathogenesis, and its adaptation to a special niche such as the gall bladder....
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Article
Open AccessVirome analysis for identification of novel mammalian viruses in bats from Southeast China
Bats have been shown as important mammal resevoirs to carry a variety of zoonotic pathogens. To analyze pathogenic species in bats from southeast coastal regions of China, we performed metagenomic sequencing t...
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Article
Open AccessGenetic Analysis of the IncX4 Plasmids: Implications for a Unique Pattern in the mcr-1 Acquisition
IncX4 plasmids are associated with the dissemination of the mcr-1 genes in Enterobacteriaceae. We screened IncX4 plasmids among 2,470 isolates of Enterobacteriaceae and determined the mcr-1 positive isolates. For...
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Article
Open AccessClonal spread of mcr-1 in PMQR-carrying ST34 Salmonella isolates from animals in China
Since initial identification in China, the widespread geographical occurrence of plasmid-mediated colistin resistance gene mcr-1 in Enterobacteriaceae has been of great concern. In this study, a total of 22 Salmo...
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Article
Open AccessGenomic insights into the ESBL and MCR-1-producing ST648 Escherichia coli with multi-drug resistance
Polymyxin acts as an ultimate line of refuge against the severe infections by multidrug-resistant Gram-negative pathogens. This conventional idea is challenged dramatically by the recent discovery of mobile co...
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Article
Open AccessFunctional definition of BirA suggests a biotin utilization pathway in the zoonotic pathogen Streptococcus suis
Biotin protein ligase is universal in three domains of life. The paradigm version of BPL is the Escherichia coli BirA that is also a repressor for the biotin biosynthesis pathway. Streptococcus suis, a leading ba...
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Article
Open AccessDeciphering a unique biotin scavenging pathway with redundant genes in the probiotic bacterium Lactococcus lactis
Biotin protein ligase (BPL) is widespread in the three domains of the life. The paradigm BPL is the Escherichia coli BirA protein, which also functions as a repressor for the biotin biosynthesis pathway. Here we ...
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Article
Origin, dissemination and entry of the pandemic Zika viruses
Zika virus (ZIKV) is a previously-neglected, but newly-emerging zoonotic pathogen that has swept most of the western hemisphere. The unexpected attention aroused worldwide lies in the explosive spread of ZIKV ...
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Article
Open AccessElectric-field-induced AFE-FE transitions and associated strain/preferred orientation in antiferroelectric PLZST
Electric-field-induced, antiferroelectric-ferroelectric (AFE-FE) phase transitions are common for AFE materials. To date, the strain and preferred orientation evolution as well as the role of the intermediate ...
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Article
Open AccessDetermination of Scrub typhus Suggests a New Epidemic Focus in the Anhui Province of China
In 2007, 19 cases of a scrub typhus epidemic occurred within a week at a sports school in Mingguang County, Anhui Province, where no previous incidence of this mite borne disease had been reported. Sero-survei...
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Article
Open AccessThe β-galactosidase (BgaC) of the zoonotic pathogen Streptococcus suis is a surface protein without the involvement of bacterial virulence
Streptococcal pathogens have evolved to express exoglycosidases, one of which is BgaC β-galactosidase, to deglycosidate host surface glycolconjucates with exposure of the polysaccharide receptor for bacterial adh...
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Open AccessAttenuation of Streptococcus suis virulence by the alteration of bacterial surface architecture
NeuB, a sialic acid synthase catalyzes the last committed step of the de novo biosynthetic pathway of sialic acid, a major element of bacterial surface structure. Here we report a functional NeuB homologue of Str...
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Article
Open AccessShock wave compression of poled Pb0.99[(Zr0.90Sn0.10)0.96Ti0.04]0.98Nb0.02O3 ceramics: Depoling currents in axial and normal modes
We used a 100-mm diameter gas gun to investigate the output currents due to the sudden depolarization of poled Pb0.99-[(Zr0.90Sn0.10)0.96Ti0.04]0.98Nb0.02O3 ceramics under shock wave compression. We conducted sho...
