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  1. Article

    Open Access

    Nicotinate-curcumin improves NASH by inhibiting the AKR1B10/ACCα-mediated triglyceride synthesis

    Nonalcoholic steatohepatitis (NASH) is a prevalent chronic liver condition. However, the potential therapeutic benefits and underlying mechanism of nicotinate-curcumin (NC) in the treatment of NASH remain unce...

    **u-lian Lin, Ya-ling Zeng, Jie Ning, Zhe Cao, Lan-lan Bu in Lipids in Health and Disease (2024)

  2. Article

    Open Access

    Solar overall water-splitting by a spin-hybrid all-organic semiconductor

    Direct solar-to-hydrogen conversion from pure water using all-organic heterogeneous catalysts remains elusive. The challenges are twofold: (i) full-band low-frequent photons in the solar spectrum cannot be har...

    **nyu Lin, Yue Hao, Yanjun Gong, Peng Zhou, Dongge Ma in Nature Communications (2024)

  3. Article

    Open Access

    Study of CP violation in B0 → DK(892)0 decays with D → Kπ(ππ), ππ(ππ), and KK final states

    A measurement of CP-violating observables associated with the interference of B0 → D0K(892)0 and B ...

    R. Aaij, A. S. W. Abdelmotteleb, C. Abellan Beteta in Journal of High Energy Physics (2024)

  4. Article

    Open Access

    Identification of QTNs, QTN-by-environment interactions, and their candidate genes for salt tolerance related traits in soybean

    Salt stress significantly reduces soybean yield. To improve salt tolerance in soybean, it is important to mine the genes associated with salt tolerance traits.

    Ying Chen, **u-Li Yue, Jian-Ying Feng, **n Gong, Wen-Jie Zhang in BMC Plant Biology (2024)

  5. No Access

    Article

    Comparative Analysis of Differentially Expressed Genes in Chondrocytes from Rats Exposed to Low Selenium and T-2 Toxin

    The aim of this study was to construct rat models of environmental risk factors for Kashin-Beck disease (KBD) with low selenium and T-2 toxin levels and to screen the differentially expressed genes (DEGs) betw...

    Yifan Wu, Yi Gong, Yanli Liu, Feihong Chen, Sijie Chen in Biological Trace Element Research (2024)

  6. No Access

    Article

    Nondestructive technique for identifying nuclides using neutron resonance transmission analysis at CSNS Back-n

    Nondestructive and noninvasive neutron assays are essential applications of neutron techniques. Neutron resonance transmission analysis (NRTA) is a powerful nondestructive method for investigating the elementa...

    Sheng-Da Tang, Yong-Hao Chen, **g-Yu Tang, Rui-Rui Fan in Nuclear Science and Techniques (2024)

  7. Article

    Open Access

    TC2N inhibits distant metastasis and stemness of breast cancer via blocking fatty acid synthesis

    Tandem C2 domains, nuclear (TC2N) is a C2 domain-containing protein that belongs to the carboxyl-terminal type (C-type) tandem C2 protein family, and acts as an oncogenic driver in several cancers. Previously,...

    **ang-lin Hao, Yang-fan Lv, De-feng Li, Fu-hai Bai in Journal of Translational Medicine (2024)

  8. Article

    Open Access

    Thermally-induced atropisomerism promotes metal-organic cage construction

    Molecular folding regulation with environmental stimuli is critical in living and artificial molecular machine systems. Herein, we described a macrocycle, cyclo[4] (1,3-(4,6-dimethyl)benzene)[4](1,3-(4,6-dimet...

    Jiaqi Liang, Shuai Lu, Yang Yang, Yun-Jia Shen, **-Ku Bai in Nature Communications (2023)

  9. Article

    Open Access

    STCF conceptual design report (Volume 1): Physics & detector

    The super τ-charm facility (STCF) is an electron–positron collider proposed by the Chinese particle physics community. It is designed to operate in a center-of-mass energy range from 2 to 7 GeV with a peak lumino...

    M. Achasov, X. C. Ai, L. P. An, R. Aliberti, Q. An, X. Z. Bai in Frontiers of Physics (2023)

  10. Article

    Open Access

    Fasting mimicking diet inhibits tumor-associated macrophage survival and pro-tumor function in hypoxia: implications for combination therapy with anti-angiogenic agent

    Recent research shows that tumor-associated macrophages (TAMs) are the primary consumers of glucose in tumor tissue, surpassing that of tumor cells. Our previous studies revealed that inhibiting glucose uptake...

    Lei Wang, Yu-jie Wang, Rong Wang, Fu-lian Gong in Journal of Translational Medicine (2023)

  11. No Access

    Article

    SHF confers radioresistance in colorectal cancer by the regulation of mitochondrial DNA copy number

    Altered mitochondrial function contributes greatly to pathogenesis and progression of colorectal cancer. In this study, we report a functional pool of Src homology 2 domain-containing F (SHF) in mitochondria c...

    Zhenyu Zhu, Meihua Gong, Weipeng Gong, Bishi Wang in Clinical and Experimental Medicine (2023)

  12. No Access

    Article

    The impact of acute-phase reaction on mortality and re-fracture after zoledronic acid in hospitalized elderly osteoporotic fracture patients

    This study involving 674 elderly osteoporotic fracture (OPF) patients undergoing orthopedic surgery investigated the long-term outcomes of acute phase reaction (APR) after initial zoledronic acid (ZOL). Those ...

    K. Lu, Y.-m. Wu, Q. Shi, Y.-q. Gong, T. Zhang, C. Li in Osteoporosis International (2023)

  13. Article

    Open Access

    Electroacupuncture-driven endogenous circulating serum exosomes as a potential therapeutic strategy for sepsis

    Sepsis poses a serious threat to human life and health, with limited options for current clinical treatments. Acupuncture plays an active role in treating sepsis. However, previous studies have focused on the ...

    **gyu Zhang, Meijuan Wang, **you Hu, Ningcen Li, PeiYong Loh in Chinese Medicine (2023)

  14. Article

    Open Access

    Association of dynamic change of triglyceride-glucose index during hospital stay with all-cause mortality in critically ill patients: a retrospective cohort study from MIMIC IV2.0

    Biomarker of insulin resistance, namely triglyceride-glucose index, is potentially useful in identifying critically ill patients at high risk of hospital death. However, the TyG index might have variations ove...

    Long Cheng, Feng Zhang, Wen**g Xue, Peng Yu, **aoyan Wang in Cardiovascular Diabetology (2023)

  15. Article

    Open Access

    Absence of critical thickness for polar skyrmions with breaking the Kittel’s law

    The period of polar domain (d) in ferroics was commonly believed to scale with corresponding film thicknesses (h), following the classical Kittel’s law of d

    Feng-Hui Gong, Yun-Long Tang, Yu-Jia Wang, Yu-Ting Chen, Bo Wu in Nature Communications (2023)

  16. Article

    Open Access

    A potential role for Giardia chaperone protein GdDnaJ in regulating Giardia proliferation and Giardiavirus replication

    Giardia duodenalis (referred to as Giardia) is a flagellated binucleate protozoan parasite, which causes one of the most common diarrheal diseases, giardiasis, worldwide. Giardia can be infected by Giardiavirus (...

    Hongbo Zhang, Chunyan Zhao, **chen Zhang, Jianhua Li, Pengtao Gong in Parasites & Vectors (2023)

  17. Article

    Open Access

    Gonadal transcriptomes reveal sex-biased expression genes associated with sex determination and differentiation in red-tail catfish (Hemibagrus wyckioides)

    Red-tail catfish (Hemibagrus wyckioides) is an important commercially farmed catfish in southern China. Males of red-tail catfish grow faster than females, suggesting that all-male catfish will produce more signi...

    Wen-Yu Wei, Yi Gong, **n-Fen Guo, Min Liu, Yu-Lin Zhou, Zhi Li, Li Zhou in BMC Genomics (2023)

  18. No Access

    Article

    Paired quasi-periodic pulsations of hard X-ray emission in a solar flare

    We investigate high time resolution data obtained by the Gravitational wave high-energy Electromagnetic Counterpart All-sky Monitor (GECAM) during the flare event on 2022 April 21 at 01:52 UT. Several subpeaks...

    Hai-Sheng Zhao, Dong Li, Shao-Lin **ong in Science China Physics, Mechanics & Astrono… (2023)

  19. No Access

    Article

    Natural killer cell-mimicking nanomaterial for overcoming the multidrug resistance of tumor via cascade catalysis

    Despite the availability and prosperity of chemotherapeutic agents, multidrug resistance (MDR) remains the paramount obstacle in antitumor chemotherapy. Here, a natural killer (NK) cell-biomimetic nanoparticle...

    Min-Jie Li **敏捷, Fan Gao 高凡, Qian-**ao Huang 黄千笑, Jun Feng 冯俊 in Science China Materials (2023)

  20. No Access

    Book and Conference Proceedings

    The Semantic Web – ISWC 2023

    22nd International Semantic Web Conference, Athens, Greece, November 6–10, 2023, Proceedings, Part II

    Terry R. Payne, Valentina Presutti, Guilin Qi in Lecture Notes in Computer Science (2023)

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