4 Result(s)
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**u-Ti Hu
Biological Psychology
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Article
Open AccessCa2+ channel blockade reduces cocaine’s vasoconstriction and neurotoxicity in the prefrontal cortex
Cocaine profoundly affects both cerebral blood vessels and neuronal activity in the brain. The vasoconstrictive effects of cocaine, concurrently with its effects on neuronal [Ca2+]i accumulation are likely to jeo...
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Article
HIV-1 Transgenic Rat Prefrontal Cortex Hyper-Excitability is Enhanced by Cocaine Self-Administration
The medial prefrontal cortex (mPFC) is dysregulated in HIV-1-infected humans and the dysregulation is enhanced by cocaine abuse. Understanding mPFC pathophysiology in this comorbid state has been hampered by t...
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Article
Repeated Cocaine Administration Decreases Calcineurin (PP2B) but Enhances DARPP-32 Modulation of Sodium Currents in Rat Nucleus Accumbens Neurons
Our previous studies have demonstrated that repeated cocaine (COC) administration reduces voltage-sensitive sodium and calcium currents (INa or VSSCs and ICa or VSCCs, respectively) in medium spiny nucleus accumb...
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Article
Dopamine Receptor Antagonists Fail to Prevent Induction of Cocaine Sensitization
We investigated the ability of dopamine D1 and D2 class receptor antagonists to prevent the induction of behavioral sensitization to cocaine. The D2 receptor antagonist eticlopride failed to prevent the induction...
