149 Result(s)

Article

Nicotinate-curcumin improves NASH by inhibiting the AKR1B10/ACCα-mediated triglyceride synthesis

Nonalcoholic steatohepatitis (NASH) is a prevalent chronic liver condition. However, the potential therapeutic benefits and underlying mechanism of nicotinate-curcumin (NC) in the treatment of NASH remain unce...

**u-lian Lin, Ya-ling Zeng, Jie Ning, Zhe Cao, Lan-lan Bu… in Lipids in Health and Disease (2024)

Article

Author Correction: A genetically encoded ratiometric indicator for tryptophan

Rongkun Tao, Kui Wang, Tian-lun Chen, **n-xin Zhang, Jian-bin Cao… in Cell Discovery (2024)

Article

RBM22 regulates RNA polymerase II 5′ pausing, elongation rate, and termination by coordinating 7SK-P-TEFb complex and SPT5

Splicing factors are vital for the regulation of RNA splicing, but some have also been implicated in regulating transcription. The underlying molecular mechanisms of their involvement in transcriptional proces...

**an Du, Wenying Qin, Chunyu Yang, Lin Dai, Mingkui San, Yingdan **a… in Genome Biology (2024)

Article

CircHIPK3 regulates fatty acid metabolism through miR-637/FASN axis to promote esophageal squamous cell carcinoma

The oncogenic role of circRNA in cancers including esophageal cancer (EC) has been well studied. However, whether and how circRNAs are involved in cancer cell metabolic processes remains largely unknown. Here,...

Shi-qiang Cao, Song-tao Xue, Wen-juan Li, Guo-sheng Hu, Zhi-gang Wu… in Cell Death Discovery (2024)

Article

LC‒MS/MS and transcriptome analyses reveal saliva components of the seed-feeding truebug Pyrrhocoris apterus

Saliva secretion is essential for successful feeding by piercing–sucking insects. Despite extensive studies of the saliva composition of phloem- and blood-feeding insects, less is known about the oral secretio...

Qian Lin, Hui-Jie Wu, Zhuo-Qi Liu, Yi Wan, Hai-Jun Xu, **-Li Zhang in Crop Health (2023)

Article

A genetically encoded ratiometric indicator for tryptophan

Rongkun Tao, Kui Wang, Tian-lun Chen, **n-xin Zhang, Jian-bin Cao… in Cell Discovery (2023)

Article

Focal ischemic stroke modifies microglia-derived exosomal miRNAs: potential role of mir-212-5p in neuronal protection and functional recovery

Ischemic stroke is a severe type of stroke with high disability and mortality rates. In recent years, microglial exosome-derived miRNAs have been shown to be promising candidates for the treatment of ischemic ...

Si-si Li, Jia-jia Wu, **ang-xin **ng, Yu-lin Li, Jie Ma, Yu-jie Duan… in Biological Research (2023)

Article

Mucin1 induced trophoblast dysfunction in gestational diabetes mellitus via Wnt/β-catenin pathway

To elucidate the role of Mucin1 (MUC1) in the trophoblast function (glucose uptake and apoptosis) of gestational diabetes mellitus (GDM) women through the Wnt/β-catenin pathway.

Shuang-Shuang Cui, ** Zhang, Lu Sun, Yu-Lin-Lan Yuan, **gyun Wang… in Biological Research (2023)

Article

A chromosome-level genome assembly of Hong Kong catfish (Clarias fuscus) uncovers a sex-determining region

Hong Kong catfish (Clarias fuscus) is an ecologically and economically important species that is widely distributed in freshwater regions of southern China. Hong Kong catfish has significant sexual growth dimorph...

Chang-Xu Tian, **ng-Hua Lin, Da-Yan Zhou, Yu Chen, Yi-Jun Shen, Ming-Hui Ye… in BMC Genomics (2023)

Article

The HOXD9-mediated PAXIP1-AS1 regulates gastric cancer progression through PABPC1/PAK1 modulation

Long non-coding RNAs (lncRNAs) have been functionally characterised in various diseases. LncRNA PAX-interacting protein 1-antisense RNA 1 (PAXIP1-AS1) has reportedly been associated with cancer development. Ho...

Jiaying Li, Miaomiao Pei, Wushuang **ao, Xuehua Liu, Linjie Hong… in Cell Death & Disease (2023)

Article

Activation of HIF-1α C-terminal transactivation domain protects against hypoxia-induced kidney injury through hexokinase 2-mediated mitophagy

The transcription factor hypoxia-inducible factor-1α (HIF-1α), as a master regulator of adaptive responses to hypoxia, possesses two transcriptional activation domains [TAD, N-terminal (NTAD), and C-terminal (...

Zuo-Lin Li, Lin Ding, Rui-**a Ma, Yue Zhang, Yi-Lin Zhang… in Cell Death & Disease (2023)

Article

Phylotype resolved spatial variation and association patterns of planktonic Thaumarchaeota in eastern Chinese marginal seas

The majority of marine ammonia oxidizers belong to Thaumarchaeota, a phylum of Archaea, which is distributed throughout the water column. Marine surface waters contain distinct thaumarchaeotal phylotypes compared...

Jiwen Liu, Fuyan Huang, Jiao Liu, **aoyue Liu… in Marine Life Science & Technology (2023)

Article

Gut microbiome dysregulation drives bone damage in broiler tibial dyschondroplasia by disrupting glucose homeostasis

Tibial dyschondroplasia (TD) with multiple incentives is a metabolic skeletal disease that occurs in fast-growing broilers. Perturbations in the gut microbiota (GM) have been shown to affect bone homoeostasis,...

Ting-ting Xu, Pan Chen, Chao-dong Zhang, Aftab Shaukat… in npj Biofilms and Microbiomes (2023)

Article

Loss of function of CMPK2 causes mitochondria deficiency and brain calcification

Brain calcification is a critical aging-associated pathology and can cause multifaceted neurological symptoms. Cerebral phosphate homeostasis dysregulation, blood-brain barrier defects, and immune dysregulatio...

Miao Zhao, Hui-Zhen Su, Yi-Heng Zeng, Yuan Sun, **n-**n Guo, Yun-Lu Li… in Cell Discovery (2022)