2,243 Result(s)

Article

Consistency, completeness and external validity of ethnicity recording in NHS primary care records: a cohort study in 25 million patients’ records at source using OpenSAFELY

Ethnicity is known to be an important correlate of health outcomes, particularly during the COVID-19 pandemic, where some ethnic groups were shown to be at higher risk of infection and adverse outcomes. The re...

Colm D. Andrews, Rohini Mathur, Jon Massey, Robin Park, Helen J. Curtis… in BMC Medicine (2024)

Article

The role of cytoreductive nephrectomy in metastatic renal cell carcinoma in immune-oncology era (SEVURO-CN): study protocol for a multi-center, prospective, randomized trial

The role of cytoreductive nephrectomy (CN) in the treatment of metastatic renal cell carcinoma (mRCC) remains unclear in the immuno-oncology (IO) era. The results of two randomized trials, CARMENA and SURTIME,...

Jee Soo Park, Jongchan Kim, **hyung Jeon, Jongsoo Lee, Won Sik Jang… in Trials (2024)

Article

Prospective validation of a mobile health application for blood pressure management in patients with hypertensive disorders of pregnancy: study protocol for a randomized controlled trial

Hypertensive disorders of pregnancy (HDP) pose significant risks to both maternal and fetal health, contributing to global morbidity and mortality. Management of HDP is complex, particularly because of concern...

Ju-Seung Kwun, **a Choi, Yeonyee E. Yoon, Hong-Mi Choi, Jee Yoon Park… in Trials (2024)

Article

Development of a novel testis-on-a-chip that demonstrates reciprocal crosstalk between Sertoli and Leydig cells in testicular tissue

The reciprocal crosstalk between testicular Sertoli and Leydig cells plays a vital role in supporting germ cell development and maintaining testicular characteristics and spermatogenesis. Conventional 2D and t...

Se-Ra Park, Myung Geun Kook, Soo-Rim Kim, Choon-Mi Lee… in Experimental & Molecular Medicine (2024)

Article

MAST4 regulates stem cell maintenance with DLX3 for epithelial development and amelogenesis

The asymmetric division of stem cells permits the maintenance of the cell population and differentiation for harmonious progress. Develo** mouse incisors allows inspection of the role of the stem cell niche ...

Dong-Joon Lee, Pyunggang Kim, Hyun-Yi Kim, **ah Park… in Experimental & Molecular Medicine (2024)

Article

FGFR3 drives Aβ-induced tau uptake

The amyloid cascade hypothesis suggests that amyloid beta (Aβ) contributes to initiating subsequent tau pathology in Alzheimer’s disease (AD). However, the underlying mechanisms through which Aβ contributes to...

Dong Kyu Kim, Kyu** Suh, Junho Park, Sang-Eun Lee… in Experimental & Molecular Medicine (2024)

Article

PHGDH: a novel therapeutic target in cancer

Serine is a key contributor to the generation of one-carbon units for DNA synthesis during cellular proliferation. In addition, it plays a crucial role in the production of antioxidants that prevent abnormal p...

Chae Min Lee, Yeseong Hwang, Minki Kim, Ye-Chan Park… in Experimental & Molecular Medicine (2024)

Article

Correction: Systematic review of fatigue severity in ME/CFS patients: insights from randomized controlled trials

Jae‑Woong Park, Byung‑** Park, **‑Seok Lee… in Journal of Translational Medicine (2024)

Article

Author Correction: Development of an anti-tauopathy mucosal vaccine specifically targeting pathologic conformers

Wenzhi Tan, Jayalakshmi Thiruppathi, Seol Hee Hong, Sao Puth, Sophea Pheng… in npj Vaccines (2024)

Article

Correction: H3.3-G34W in giant cell tumor of bone functionally aligns with the exon choice repressor hnRNPA1L2

Eunbi Lee, Yoon Jung Park, Anders M. Lindroth in Cancer Gene Therapy (2024)

Article

Chemotherapy-related cardiotoxicity and its symptoms in patients with breast cancer: a sco** review

Chemotherapy-related cardiotoxicity is a significant concern because it is a major cause of morbidity. This study aimed to provide in-depth information on the symptoms of chemotherapy-related cardiotoxicity (C...

Hyunjoo Kim, Bomi Hong, Sanghee Kim, Seok-Min Kang, Jeongok Park in Systematic Reviews (2024)

Article

Author Correction: Inhibition of lysine acetyltransferase KAT6 in ER⁺HER2⁻ metastatic breast cancer: a phase 1 trial

Toru Mukohara, Yeon Hee Park, David Sommerhalder, Kan Yonemori… in Nature Medicine (2024)

Article

Author Correction: A shifting role of thalamocortical connectivity in the emergence of cortical functional organization

Shinwon Park, Koen V. Haak, Stuart Oldham, Hanbyul Cho… in Nature Neuroscience (2024)

Article

Transcriptome analysis of cynomolgus macaques throughout their lifespan reveals age-related immune patterns

Despite the different perspectives by diverse research sectors spanning several decades, aging research remains uncharted territory for human beings. Therefore, we investigated the transcriptomic characteristi...

Hyeon-Mu Cho, Se-Hee Choe, Ja-Rang Lee, Hye-Ri Park, Min-Gyeong Ko… in npj Aging (2024)

Article

Association between exercise habits and incident type 2 diabetes mellitus in patients with thyroid cancer: nationwide population-based study

We investigated the association between exercise habits before or after thyroidectomy and incident type 2 diabetes mellitus (T2DM) in patients with thyroid cancer.

Jiyun Park, **-Hyung Jung, Hyunju Park, Young Shin Song, Soo-Kyung Kim… in BMC Medicine (2024)

Article

Role of SYT11 in human pan-cancer using comprehensive approaches

Synaptotagmin 11 (SYT11) plays a pivotal role in neuronal vesicular trafficking and exocytosis. However, no independent prognostic studies have focused on various cancers. In this study, we aimed to summarize ...

Kyunghee Noh, Hyunji Choi, Eun-Hye Jo, Wonbeak Yoo… in European Journal of Medical Research (2024)

Article

Correction: Recent progress in DNA data storage based on high-throughput DNA synthesis

Seokwoo Jo, Haewon Shin, Sung-yune Joe, David Baek… in Biomedical Engineering Letters (2024)

Article

Development of an anti-tauopathy mucosal vaccine specifically targeting pathologic conformers

Alzheimer’s disease (AD) and related tauopathies are associated with pathological tau protein aggregation, which plays an important role in neurofibrillary degeneration and dementia. Targeted immunotherapy to ...

Wenzhi Tan, Jayalakshmi Thiruppathi, Seol Hee Hong, Sao Puth, Sophea Pheng… in npj Vaccines (2024)

Article

The identification of effective tumor-suppressing neoantigens using a tumor-reactive TIL TCR-pMHC ternary complex

Neoantigens are ideal targets for cancer immunotherapy because they are expressed de novo in tumor tissue but not in healthy tissue and are therefore recognized as foreign by the immune system. Advances in nex...

Sang Hoon Kim, Bo Ryeong Lee, Sung-Min Kim… in Experimental & Molecular Medicine (2024)

Article

Author Correction: Regulation of autophagy by perilysosomal calcium: a new player in β-cell lipotoxicity

Ha Thu Nguyen, Andreas Wiederkehr, Claes B. Wollheim… in Experimental & Molecular Medicine (2024)