-
Article
Evaluation of the validity of the US EPA's cancer risk assessment of arsenic for low-level exposures: a likelihood ratio approach
Skin cancers associated with ingesting of arsenic have been documented since the 19th century. A study in the southwestern coastal area of Taiwan where people drank well water containing arsenic is generally r...
-
Article
Arsenic in Drinking Water and Bladder Cancer: Comparison between Studies Based on Cancer Registry and Death Certificates
Associations between arsenic in drinking water and bladder cancer in an area along the southwest coast of Taiwan have been documented for decades. Several ecologic studies were conducted to assess the dose-res...
-
Article
Determination of momordicoside A in bitter melon by high-performance liquid chromatography after solid-phase extraction
Momordicoside A has been determined by solid-phase extraction (SPE) on a Envi Carb cartridge (3 mL, 250mg) then high-performance liquid chromatography (HPLC) on a C18 column (4.6 mm×250 mm, 5 μm particle) with ac...
-
Article
Arsenic in drinking water and skin cancers: cell-type specificity (Taiwan, R.O.C.)
Objective: The association between arsenic ingestion and cancer has been documented for more than a century. Previous studies showed that the carcinogenic effects of arsenic on the urinary system are cell-type s...
-
Article
Lipid peroxidation and cell death mechanisms in pulmonary epithelial cells induced by peroxynitrite and nitric oxide
Nitric oxide (NO) is an environmental pollutant found in smog and cigarette smoke. Recently, NO has been discovered to act as a molecular messenger, mediating various physiological functions. However, when an...
-
Article
Arsenic level in drinking water and mortality of lung cancer (Taiwan)
Objective: Lung cancers have been observed among patients of arsenic intoxication since the 1950s, but data on the dose–response relationship were limited. In order to obtain such data, a study was conducted in ...
-
Article
Frequent analgesics consumption in migraineurs: comparison between chronic and episodic migraineurs
To assess the frequent consumption of symptomatic medications in migraineurs, we consecutively recruited 536 migraineurs from a headache clinic. Among them, 194 (36.2%) had chronic migraine and 342 had episodi...
-
Article
Increased Risk of Develo** Hepatocellular Carcinoma Associated with Carriage of the TNF2 Allele of the −308 Tumor Necrosis Factor-α Promoter Gene
Background and Aims: Tumor necrosis factor-α(TNF-α) is a cytokine that may act as an endogenous tumor promoter. A genetic polymorphism of TNF-α at position −308 of the promoter region, which includes TNF1 (−308G...
-
Article
Numerical simulation of thermo-mechanical fatigue properties for particulate reinforced composites
In this paper, a two dimensional Voronoi cell element, formulated with creep, thermal and plastic strain, is applied for the numerical simulation of thermo-mechanical fatigue behavior for particulate reinforce...
-
Article
Open AccessTear secretion dysfunction among women workers engaged in light-on tests in the TFT-LCD industry
The TFT-LCD (thin film transistor liquid crystal display) industry is rapidly growing in Taiwan and many other countries. A large number of workers, mainly women, are employed in the light-on test process to d...
-
Article
Alterations in health examination items and skin symptoms from exposure to ultra-low humidity
Several lines of evidence have shown that insufficient humidity could result in health problems but no studies have been performed in ultra-low humidity (ULH) environments. The aims of this study are to invest...
-
Article
Hypoxia-inducible factor-1α correlates with MET and metastasis in node-negative breast cancer
The mechanism of tumor hypoxia promoting metastasis remains uncertain. Hypoxia-inducible factor-1α (HIF-1α) is a key mediator of the cellular response to hypoxia and binds the met promoter, resulting in increased...
-
Article
Open AccessVariations of care quality for infectious pulmonary tuberculosis in Taiwan: a population based cohort study
Effective and efficient care is required to prevent the spread of infectious pulmonary tuberculosis (PTB). We attempted to compare care quality among different healthcare institutions in Southern Taiwan.
-
Article
Open AccessA cross-species alignment tool (CAT)
The main two sorts of automatic gene annotation frameworks are ab initio and alignment-based, the latter splitting into two sub-groups. The first group is used for intra-species alignments, among which are succes...
-
Article
Effect of different dietary raw to pre-gelatinized starch ratios on growth performance, feed utilization and body composition of juvenile yellowfin seabream (Sparus latus)
The effects of different ratios of dietary raw to pre-gelatinized starch on the growth performance, feed utilization and body composition of juvenile yellowfin seabream (Sparus latus) were evaluated during a 10-w...
-
Article
Open AccessPresentations of patients of poisoning and predictors of poisoning-related fatality: Findings from a hospital-based prospective study
Poisoning is a significant public health problem worldwide and is one of the most common reasons for visiting emergency departments (EDs), but factors that help to predict overall poisoning-related fatality ha...
-
Article
Open AccessWater disinfection by-products and the risk of specific birth defects: a population-based cross-sectional study in Taiwan
Recent findings suggest that exposure to disinfection by-products may increase the risk of birth defects. Previous studies have focused mainly on birth defects in general or groups of defects. The objective of...
-
Article
Open AccessThe diploid genome sequence of an Asian individual
Here we present the first diploid genome sequence of an Asian individual. The genome was sequenced to 36-fold average coverage using massively parallel sequencing technology. We aligned the short reads onto th...
-
Article
Using Rasch Analysis to Validate the Revised PSQI to Assess Sleep Disorders in Taiwan’s Hi-tech Workers
The Pittsburgh Sleep Quality Index (PSQI) is an effective instrument for measuring the quality of sleep in older adults. In this study, we used Rasch analysis to validate the items of the revised PSQI (SC_PSQI...
-
Article
Climate variability of cold surge and its impact on the air quality of Taiwan
Climate change has been receiving wide attention in the last few decades. In order to quantify the climate variability of extreme weather events and their possible impacts on weather parameters and air quality...
