-
Article
Dynamic modeling of three-dimensional muscle wrap** based on absolute nodal coordinate formulation
Muscle wrap** influences its moment arm and alters the dynamic response of the musculoskeletal system. Conventional musculoskeletal multibody models often simplify muscle wrap** as the shortest path proble...
-
Article
Open AccessKnockdown of AMIGO2 suppresses proliferation and migration through regulating PPAR-γ in bladder cancer
This study aims to reveal the relationship between AMIGO2 and proliferation, migration and tumorigenicity of bladder cancer, and explore the potential molecular mechanisms.
-
Article
Open AccessNeoadjuvant chemotherapy with or without camrelizumab in resectable esophageal squamous cell carcinoma: the randomized phase 3 ESCORT-NEO/NCCES01 trial
Recent single-arm studies involving neoadjuvant camrelizumab, a PD-1 inhibitor, plus chemotherapy for resectable locally advanced esophageal squamous cell carcinoma (LA-ESCC) have shown promising results. This...
-
Article
Open AccessBiosynthesis of cupric oxide nanoparticles: its antiviral activities against TMV by directly destroying virion and inducing plant resistance
Tobacco mosaic virus (TMV) is widely recognized as one of the most important plant viruses, causing significant agricultural losses in terms of both quality and yield worldwide each year. This study demonstrat...
-
Article
Open AccessDual polarization-enabled ultrafast bulk photovoltaic response in van der Waals heterostructures
The bulk photovoltaic effect (BPVE) originating from spontaneous charge polarizations can reach high conversion efficiency exceeding the Shockley-Queisser limit. Emerging van der Waals (vdW) heterostructures p...
-
Article
Efficient explicit time integration algorithms for non-spherical granular dynamics on group S(3)
Discrete element method (DEM) is a powerful tool for the dynamic simulation of irregular non-spherical particle systems. The efficient integration of the rotational motions of numerous particles in DEM poses a...
-
Article
Topology optimization for improving stability of a rotating thin plate
Increasing the critical angular speed of a rotating structure can enlarge working range and enhance operating safety. To achieve this purpose, a topology optimization approach is proposed to increase the criti...
-
Article
Participation constraints in first-price auctions
We study the endogenous participation problem when bidders are characterized by a two-dimensional private information on valuations and participation costs in first-price auctions. Bidders participate whenever...
-
Article
Functions of violaxanthin de-epoxidase-related (VDR) in the photoprotective response to high-light stress
The xanthophyll cycle plays a pivotal role in protecting plants and algae against photodamage. Although the resistance of the violaxanthin de-epoxidase enzyme (VDE) to high light stress in the xanthophyll cycl...
-
Article
Open AccessSurvival outcomes of neoadjuvant immunochemotherapy versus chemotherapy for locally advanced esophageal squamous cell carcinoma
Neoadjuvant chemotherapy (NCT) is the standard preoperative treatment for resectable locally advanced esophageal squamous cell carcinoma (ESCC). Some studies reported neoadjuvant immunochemotherapy (NICT) coul...
-
Article
Exploring grazing intensity effects: nitrogen uptake in grassland species and soil carbon allocation
Grazing drives carbon (C) and nitrogen (N) dynamics of grasslands through livestock trampling, defoliation, and excretion. Still, the responses of N uptake by plant species and simultaneous C allocation into t...
-
Article
Open AccessInfluence of different position modal parameters on milling chatter stability of orthopedic surgery robots
This research is dedicated to exploring the dynamics of milling chatter stability in orthopedic surgery robots, focusing on the impact of position modal parameters on chatter stability. Initially, we develop a...
-
Article
Dynamic modeling of flexible multibody systems with complex geometry via finite cell method of absolute nodal coordinate formulation
Practical multibody systems usually consist of flexible bodies of complex shapes, but existing dynamic modeling methods work efficiently only for the systems with bodies of simple and regular shapes. This stud...
-
Article
Open AccessOnly anti-GM4 antibody positivity in a Chinese girl with overlap** MFS/GBS: a case report
Guillain-Barré syndrome (GBS), as the most common cause of acute flaccid paralysis worldwide, is considered a part of a clinical spectrum in which discrete, complete, or incomplete forms of GBS and overlap**...
-
Article
Open AccessTherapeutic potential of gelatine methacrylate hydrogels loaded with macrophage-derived exosomes for accelerating angiogenesis and cutaneous wound healing
Extensive studies demonstrate that macrophage response plays an important role in regulating angiogenesis via a paracrine way, which is crucial for skin wound repair. This study isolated and characterized nano...
-
Article
Consistent epistemic planning for multiagent deep reinforcement learning
Multiagent cooperation in a partially observable environment without communication is difficult because of the uncertainty of agents. Traditional multiagent deep reinforcement learning (MADRL) algorithms fail ...
-
Article
A dry-wet teleconnection between southwestern and northeastern China in winter and early spring
Global climate change has led to more frequent and intense dry and wet extremes, causing considerable socio-economic losses, but whether these extremes in distant regions are linked and what mechanisms are dri...
-
Article
Open AccessLong Non-coding RNA X-Inactive Specific Transcript Promotes Esophageal Squamous Cell Carcinoma Progression via the MicroRNA 34a/Zinc Finger E-box–Binding Homeobox 1 Pathway
The long non-coding RNA X-inactive specific transcript (XIST) plays a crucial role in transcriptional silencing of the X chromosome. Zinc finger E-box-binding homeobox 1 (ZEB1) is a transcription factor involv...
-
Article
Cross-sectional network analysis of plasma proteins/metabolites correlated with pathogenesis and therapeutic response in acute promyelocytic leukemia
The treatment of PML/RARA+ acute promyelocytic leukemia (APL) with all-trans-retinoic acid and arsenic trioxide (ATRA/ATO) has been recognized as a model for translational medicine research. Though an altered ...
-
Article
Will the Globe Encounter the Warmest Winter after the Hottest Summer in 2023?
In the boreal summer and autumn of 2023, the globe experienced an extremely hot period across both oceans and continents. The consecutive record-breaking mean surface temperature has caused many to speculate u...
