32 Result(s)

Article

Circular RNA circFCHO2(hsa_circ_0002490) promotes the proliferation of melanoma by directly binding to DND1

Circular RNAs (circRNAs) have been documented to play crucial roles in the biology of various cancers. However, their investigation in melanoma is still at an early stage, particularly as a broader mechanism b...

Yang Yang, Jianrui Li, Chuanyuan Wei, Lu Wang, Zixu Gao… in Cell Biology and Toxicology (2024)

Article

Delineating the early dissemination mechanisms of acral melanoma by integrating single-cell and spatial transcriptomic analyses

Acral melanoma (AM) is a rare subtype of melanoma characterized by a high incidence of lymph node (LN) metastasis, a critical factor in tumor dissemination and therapeutic decision-making. Here, we employ sing...

Chuanyuan Wei, Wei Sun, Kangjie Shen, **gqin Zhong, Wanlin Liu… in Nature Communications (2023)

Article

Decoding the metastatic potential and optimal postoperative adjuvant therapy of melanoma based on metastasis score

Metastasis is a formidable challenge in the prognosis of melanoma. Accurately predicting the metastatic potential of non-metastatic melanoma (NMM) and determining effective postoperative adjuvant treatments fo...

Kangjie Shen, Wenyu Song, Hongye Wang, Lu Wang, Yang Yang… in Cell Death Discovery (2023)

Article

The tooth movement efficiency of different orthodontic thermoplastics for clear aligners: study protocol for a randomized controlled clinical trial

With regard to the esthetics and comfort of orthodontic treatment, the requirement for removable clear aligners (CAs) is increasing. Unlike conventional fixed orthodontic appliances, CAs were made of thermopla...

Chuangchuang Mu, Bing**g Sun, Zhicheng Gong, Yuanyuan Wei, Li Chen, Wei Zhang… in Trials (2023)

Article

Prediction of survival and immunotherapy response by the combined classifier of G protein-coupled receptors and tumor microenvironment in melanoma

Melanoma is the deadliest form of skin tumor, and G protein-coupled receptors (GPCRs) play crucial roles in its carcinogenesis. Furthermore, the tumor microenvironment (TME) affects the overall survival (OS) a...

Kangjie Shen, Qiangcheng Wang, Lu Wang, Yang Yang… in European Journal of Medical Research (2023)

Article

Equilibrium electron beam parameters of the High Energy Photon Source

The physics design of the High Energy Photon Source (HEPS) was finished after many times of iteration. Hereby, the typical equilibrium electron beam parameters corresponding to the proposed two baseline operat...

Haisheng Xu, Cai Meng, Yuemei Peng… in Radiation Detection Technology and Methods (2023)

Article

Mori fructus aqueous extracts attenuates liver injury by inhibiting ferroptosis via the Nrf2 pathway

Liver fibrosis and hepatocellular carcinogenesis secondary to liver fibrosis are serious liver diseases with no effective treatments. Mori fructus aqueous extracts (MFAEs) have served as successful treatments for...

Yuanyuan Wei, Chen Gao, Huiru Wang… in Journal of Animal Science and Biotechnology (2023)

Article

Integrating terrestrial and aquatic ecosystems to constrain estimates of land-atmosphere carbon exchange

In this Perspective, we put forward an integrative framework to improve estimates of land-atmosphere carbon exchange based on the accumulation of carbon in the landscape as constrained by its lateral export th...

Joan P. Casas-Ruiz, Pascal Bodmer, Kelly Ann Bona, David Butman… in Nature Communications (2023)

Article

Diel variations in planktonic ciliate community structure in the northern South China Sea and tropical Western Pacific

Though diel variations are geographically widespread phenomena among phytoplankton and zooplankton, knowledge is limited regarding diel variations in planktonic ciliate (microzooplankton) community structure. ...

Chaofeng Wang, Yi Dong, Michel Denis, Yuanyuan Wei, Haibo Li… in Scientific Reports (2023)

Article

The impact of pharmacist practice of medication therapy management in ambulatory care: an experience from a comprehensive Chinese hospital

With the reform of medical system in China, Bei**g municipal hospitals explored a new pharmaceutical care model and set up medication therapy management services (MTMs) in ambulatory care since 2019. We were ...

Qingli Meng, Lulu Sun, Yingjie Ma, Yuanyuan Wei, **aowei Ma… in BMC Health Services Research (2023)

Article

GSDME-mediated pyroptosis promotes the progression and associated inflammation of atherosclerosis

Pyroptosis, a type of Gasdermin-mediated cell death, contributes to an exacerbation of inflammation. To test the hypothesis that GSDME-mediated pyroptosis aggravates the progression of atherosclerosis, we gene...

Yuanyuan Wei, Beidi Lan, Tao Zheng, Lin Yang, **aoxia Zhang… in Nature Communications (2023)

Article

A life cycle and product type based estimator for quantifying the carbon stored in wood products

Timber harvesting and industrial wood processing laterally transfer the carbon stored in forest sectors to wood products creating a wood products carbon pool. The carbon stored in wood products is allocated to...

**nyuan Wei, Jianheng Zhao, Daniel J. Hayes… in Carbon Balance and Management (2023)

Article

EGFR, HER2, and HER3 protein expression in paired primary tumor and lymph node metastasis of colorectal cancer

Due to the difficulty in sampling of metastatic tumors, patient selection is commonly based on results of primary tumor samples when metastatic samples are not available. However, due to tumor heterogeneity, m...

Peng Ye, Fanghua Li, Yuanyuan Wei, Yihao Zhang, Jianing Cui, Rui Dai… in Scientific Reports (2022)

Article

Exosomes for gene therapy effectively inhibit the endothelial-mesenchymal transition in mouse aortic endothelial cells

Heterotopic ossification (HO) can limit joint activity, causes ankylosis and impairs the function and rehabilitation of patients. Endothelial to mesenchymal transition (EndMT) plays an important role in the pa...

Zhenyuan Wei, Yang Zhao, Peichun Hsu, Shang Guo, Chi Zhang… in BMC Musculoskeletal Disorders (2021)

Article

PSMC2 knockdown suppressed tumor progression of skin cutaneous melanoma

Skin cutaneous melanoma (SKCM) is the most lethal tumor among three of the major malignant cancers of the skin. The mechanism underlying the malignant biological behaviors of SKCM is not fully clear. Our study...

Yanwen Yang, Fazhi Qi, Chuanyuan Wei, Jiaqi Liu, Yong Zhang… in Cell Death Discovery (2021)

Article

Targeted Sub-Attomole Cancer Biomarker Detection Based on Phase Singularity 2D Nanomaterial-Enhanced Plasmonic Biosensor

Article

Coexistence of valley polarization and Chern insulating states in MoS₂ monolayers with n-p codo**

The electronic and topological properties of MoS₂ monolayers with n-p codo** effect are investigated by using first-principles calculations. Two types of the doped Nb atoms play the roles of the p-type and n-ty...

**nyuan Wei, Jiayong Zhang, Bao Zhao, Zhongqin Yang in Scientific Reports (2020)

Article

Telocytes inhibited inflammatory factor expression and enhanced cell migration in LPS-induced skin wound healing models in vitro and in vivo

Cell proliferation and death are key components of wound healing and tissue repair. Telocytes (TCs) represent a newly discovered cell type that can protect tissue from acute injury via cell–cell communication ...

Lu Wang, Dongli Song, Chuanyuan Wei, Cheng Chen… in Journal of Translational Medicine (2020)

Article

CCL14 serves as a novel prognostic factor and tumor suppressor of HCC by modulating cell cycle and promoting apoptosis

CCL14 is a member of CC chemokines and its role in hepatocellular carcinoma (HCC) is still unknown. In this study, CCL14 expression were analyzed by tissue microarray (TMA) including 171 paired tumor and perit...

Mengxuan Zhu, Weiyue Xu, Chuanyuan Wei, **g Huang, Jietian Xu… in Cell Death & Disease (2019)

Article

Single-molecule long-read sequencing facilitates shrimp transcriptome research

Although shrimp are of great economic importance, few full-length shrimp transcriptomes are available. Here, we used Pacific Biosciences single-molecule real-time (SMRT) long-read sequencing technology to gene...

Digang Zeng, **uli Chen, **xia Peng, Chunling Yang, Min Peng… in Scientific Reports (2018)