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Article
Fixed-time tracking control for state-constrained nonstrict-feedback systems without feasibility conditions
This paper investigates the fixed-time tracking control for a class of state-constrained nonstrict-feedback nonlinear systems without involving the feasibility conditions. Based on nonlinear map**, a nonline...
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Article
Open AccessTudor-SN promotes cardiomyocyte proliferation and neonatal heart regeneration through regulating the phosphorylation of YAP
The neonatal mammalian heart exhibits considerable regenerative potential following injury through cardiomyocyte proliferation, whereas mature cardiomyocytes withdraw from the cell cycle and lose regenerative ...
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Article
Open AccessOral administration of probiotic spore ghosts for efficient attenuation of radiation-induced intestinal injury
Radiation-induced intestinal injury is the most common side effect during radiotherapy of abdominal or pelvic solid tumors, significantly impacting patients’ quality of life and even resulting in poor prognosi...
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Article
Decitabine-containing conditioning improved outcomes for children with higher-risk myelodysplastic syndrome undergoing allogeneic hematopoietic stem cell transplantation
Myelodysplastic syndrome (MDS) is a rare clonal hematopoietic disorder in children. The risk stratification system and treatment strategy for adults are unfit for children. The role of hypomethylating agents (...
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Article
Open AccessJMJD3 regulate H3K27me3 modification via interacting directly with TET1 to affect spermatogonia self-renewal and proliferation
In epigenetic modification, histone modification and DNA methylation coordinate the regulation of spermatogonium. Not only can methylcytosine dioxygenase 1 (TET1) function as a DNA demethylase, converting 5-me...
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Article
Open AccessVascular injury activates the ELK1/SND1/SRF pathway to promote vascular smooth muscle cell proliferative phenotype and neointimal hyperplasia
Vascular smooth muscle cell (VSMC) proliferation is the leading cause of vascular stenosis or restenosis. Therefore, investigating the molecular mechanisms and pivotal regulators of the proliferative VSMC phen...
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Chapter and Conference Paper
CMed-Baichuan: Task Explanation-Enhanced Prompt Method on PromptCBLUE Benchmark
Large Language Models (LLMs) have received widespread attention from academia and industry for their excellent performance on NLP tasks. Due to the knowledge-intensive nature of the medical field, previous stu...
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Chapter and Conference Paper
Improving Out-of-Distribution Detection with Margin-Based Prototype Learning
Deep Neural Networks often make overconfident predictions when encountering out-of-distribution (OOD) data. Previous prototype-based methods significantly improved OOD detection performance by optimizing the r...
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Article
Causes of death and treatment-related mortality in newly diagnosed childhood acute lymphoblastic leukemia treatment with Chinese Children’s Cancer Group study ALL-2015
To investigate the possible risk factors for death at post-treatment in children with acute lymphoblastic leukemia (ALL). A multivariate competing risk analysis was performed to retrospectively analyze the dat...
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Article
Open AccessA novel c-Met/TRK inhibitor 1D228 efficiently inhibits tumor growth by targeting angiogenesis and tumor cell proliferation
Multiple tumors are synergistically promoted by c-Met and TRK, and blocking their cross-signalling pathway may give better effects. In this study, we developed a tyrosine kinase inhibitor 1D228, which exhibite...
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Article
Risk posed to vegetation net primary productivity by drought on the Mongolian Plateau
The increasing frequency of recent droughts has an adverse effect on the ecosystem of the Mongolian Plateau. The growth condition of NPP is considered an indicator of the ecological function. Therefore, identi...
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Article
An experimental study for evaluation of collapsible loess roadbed replacement method using lightweight soil
Water is one of the most significant variables that contribute to loess collapse, hence in collapsible loess areas, stringent waterproofing measures are frequently employed to limit loess roadbed collapse. Dur...
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Article
The effectiveness of virtual reality games in improving cognition, mobility, and emotion in elderly post-stroke patients: a systematic review and meta-analysis
This review is aimed to assess the effectiveness of virtual reality (VR) games on cognition, mobility, and emotion in elderly stroke patients. We selected relevant articles from eight databases from 2011 to 20...
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Article
Investigating the curing time effect on water retention property and microstructure of lime-treated Ili loess
Water retention is an important soil property affecting the hydro-mechanical behavior of unsaturated soils. This study investigated the water retention property and the microstructure of lime-treated Ili loess...
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Article
Open AccessNon-thermal evolution of dense plasmas driven by intense x-ray fields
The advent of x-ray free-electron lasers has enabled a range of new experimental investigations into the properties of matter driven to extreme conditions via intense x-ray-matter interactions. The femtosecond...
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Article
Role of Pseudomonas fluorescens FSYZ01 on the corrosion behavior of Q235B carbon steel in oilfield produced water
The corrosion behavior of Q235B carbon steel is investigated in water, LB medium, and oilfield produced water adding Pseudomonas fluorescens FSYZ01. After immersion at 30 °C for 13 days, the weight loss of carbon...
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Article
Myokine, a key cytokine for physical exercise to alleviate sarcopenic obesity
Skeletal muscle has a robust endocrine function as a powerful organ and can secrete and release cytokines or polypeptides known as myokines. These myokines have significant regulatory effects on signal transdu...
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Article
Control of Antagonistic McKibben Muscles via a Bio-inspired Approach
McKibben muscles are increasingly used in many robotic applications due to their advantages of lightweight, compliant, and skeletal muscles-like behaviours. However, there are still huge challenges in the moti...
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Article
Open AccessArginase: shedding light on the mechanisms and opportunities in cardiovascular diseases
Arginase, a binuclear manganese metalloenzyme in the urea, catalyzes the hydrolysis of L-arginine to urea and L-ornithine. Both isoforms, arginase 1 and arginase 2 perform significant roles in the regulation o...
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Article
Relationship between ambient air pollution and preterm birth: a retrospective birth cohort study in Yan’an, China
Preterm birth (PTB) has been associated with exposure to air pollution, but it is unclear whether effects might vary among air pollution sources in a valley city, and yet few studies have investigated refined ...
