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  1. No Access

    Article

    Identification of genetic variants in m6A modification genes associated with pancreatic cancer risk in the Chinese population

    N6-Methyladenosine (m6A) is the most prevalent modification of RNA in eukaryotes, and is associated with many cellular processes and even the development of cancers. We hypothesized that single-nucleotide polymor...

    **ting Ying, Yao Li, Nan Yang, **aoyang Wang, Haoxue Wang… in Archives of Toxicology (2021)

  2. No Access

    Article

    Functional characterization of a low-frequency V1937I variant in FASN associated with susceptibility to esophageal squamous cell carcinoma

    Metabolic reprogramming has been regarded as one of the core hallmarks of cancer and increased de novo fatty acid synthesis has been documented in multiple tumors including esophageal squamous cell carcinoma (...

    **aoyang Wang, Jianbo Tian, Qianyu Zhao, Nan Yang, **ting Ying… in Archives of Toxicology (2020)

  3. No Access

    Article

    Three functional variants were identified to affect RPS24 expression and significantly associated with risk of colorectal cancer

    GWAS-identified 10q22.3 loci with lead SNP rs704017 are significantly associated with CRC risk in both Asian and European populations. However, the functional mechanism of this region is unclear. In this study...

    Danyi Zou, Hongli Zhang, Juntao Ke, Jiaoyuan Li, Ying Zhu… in Archives of Toxicology (2020)