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Article
A weavable and wearable polymer ultrasonic transducer with a large bandwidth
The rise of Internet of Things technologies has promoted the rapid advancement of wearable health monitoring devices. While medical ultrasound technology holds promise for long-term monitoring to detect critic...
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Article
Robust Fiber Strain Sensor by Designing Coaxial Coiling Structure with Mutual Inductance Effect
Fiber strain sensors with robust sensing performance are indispensable for human–machine interactions in the electronic textiles. However, current fiber strain sensors are confronted with the challenges of una...
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Article
Open AccessThe risk of mpox importation and subsequent outbreak potential in Chinese mainland: a retrospective statistical modelling study
The 2022–2023 mpox (monkeypox) outbreak has spread rapidly across multiple countries in the non-endemic region, mainly among men who have sex with men (MSM). In this study, we aimed to evaluate mpox’s importat...
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Article
Open AccessBayesian Mendelian randomization with an interval causal null hypothesis: ternary decision rules and loss function calibration
We enhance the Bayesian Mendelian Randomization (MR) framework of Berzuini et al. (Biostatistics 21(1):86–101, 2018) by allowing for interval null causal hypotheses, where values of the causal effect parameter...
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Article
Open AccessTumor microenvironment remodeling plus immunotherapy could be used in mesenchymal-like tumor with high tumor residual and drug resistant rate
Epithelial-mesenchymal transition (EMT) is a common process during tumor progression and is always related to residual tumor, drug resistance and immune suppression. However, considering the heterogeneity in E...
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Article
Macroalgae culture–induced carbon sink in a large cultivation area of China
Macroalgae culture–induced carbon sink in sediments has been little investigated. Here, total organic carbon (TOC), total nitrogen (TN), and δ13C were examined in sediments in a cultivation field of macroalgae (k...
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Article
A DNA nanodevice for map** sodium at single-organelle resolution
Cellular sodium ion (Na+) homeostasis is integral to organism physiology. Our current understanding of Na+ homeostasis is largely limited to Na+ transport at the plasma membrane. Organelles may also contribute to...
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Article
Insulator Defects Detection for Aerial Photography of the Power Grid Using You Only Look Once Algorithm
The safe operation of the power grid system depends partly on regular inspections of transmission lines, in which the insulator is one of the most important inspections objects. The manual inspection of transm...
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Protocol
SNPD-CRISPR: Single Nucleotide Polymorphism-Distinguishable Repression or Enhancement of a Target Gene Expression by CRISPR System
A wide range of diseases, including cancer, autoimmune diseases, or neurodegenerative diseases, have been associated with single nucleotide mutations in their causative genes. Clustered regularly interspaced s...
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Article
Open AccessPromising therapeutic aspects in human genetic imprinting disorders
Genomic imprinting is an epigenetic phenomenon of monoallelic gene expression pattern depending on parental origin. In humans, congenital imprinting disruptions resulting from genetic or epigenetic mechanisms ...
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Article
Deep Metallogenic prediction model construction of the **ongcun no. II orebody based on the DNN algorithm
With the continuous mining and gradual reduction of shallow deposits, deep prospecting has become a new global prospecting trend. In addition, with the development of artificial intelligence, deep learning pro...
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Article
Open AccessModeling transmission of SARS-CoV-2 Omicron in China
Having adopted a dynamic zero-COVID strategy to respond to SARS-CoV-2 variants with higher transmissibility since August 2021, China is now considering whether, and for how long, this policy can remain in plac...
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Article
Open AccessBayesian mendelian randomization with study heterogeneity and data partitioning for large studies
Mendelian randomization (MR) is a useful approach to causal inference from observational studies when randomised controlled trials are not feasible. However, study heterogeneity of two association studies requ...
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Article
Research on landslide hazard spatial prediction models based on deep neural networks: a case study of northwest Sichuan, China
The Wenchuan earthquake in 2008 induced thousands of geological hazards. Among them, earthquake-induced landslides are extremely disastrous, causing considerable social and economic losses and damage to the ec...
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Article
Open AccessGlobal landscape of SARS-CoV-2 genomic surveillance and data sharing
Genomic surveillance has shaped our understanding of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants. We performed a global landscape analysis on SARS-CoV-2 genomic surveillance and genom...
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Chapter and Conference Paper
Learn-to-Decompose: Cascaded Decomposition Network for Cross-Domain Few-Shot Facial Expression Recognition
Most existing compound facial expression recognition (FER) methods rely on large-scale labeled compound expression data for training. However, collecting such data is labor-intensive and time-consuming. In thi...
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Article
Identification of genetic variants in m6A modification genes associated with pancreatic cancer risk in the Chinese population
N6-Methyladenosine (m6A) is the most prevalent modification of RNA in eukaryotes, and is associated with many cellular processes and even the development of cancers. We hypothesized that single-nucleotide polymor...
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Article
Open AccessOverlap**-sample Mendelian randomisation with multiple exposures: a Bayesian approach
Mendelian randomization (MR) has been widely applied to causal inference in medical research. It uses genetic variants as instrumental variables (IVs) to investigate putative causal relationship between an exp...
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Article
Open AccessUsefulness of three-dimensional printing of superior mesenteric vessels in right hemicolon cancer surgery
The anatomy of the superior mesenteric vessels is complex, yet important, for right-sided colorectal surgery. The usefulness of three-dimensional (3D) printing of these vessels in right hemicolon cancer surger...
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Article
Functional characterization of a low-frequency V1937I variant in FASN associated with susceptibility to esophageal squamous cell carcinoma
Metabolic reprogramming has been regarded as one of the core hallmarks of cancer and increased de novo fatty acid synthesis has been documented in multiple tumors including esophageal squamous cell carcinoma (...