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Open AccessAnalysis of clinicopathologic and imaging features of dual-phenotype hepatocellular carcinoma
Dual-phenotype hepatocellular carcinoma (DPHCC) is a new subtype of hepatocellular carcinoma (HCC). This study aimed to investigate the relationship between the computerized tomography scan (CT) imaging and cl...
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Article
Open AccessBroadband stripline Lenz lens achieves 11 × NMR signal enhancement
A Lenz lens is an electrically passive conductive element that, when placed in a time-varying magnetic field, acts as a magnetic flux concentrator or a magnetic lens. In the realm of nuclear magnetic resonance...
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Article
Open AccessFlexible and broadband colloidal quantum dots photodiode array for pixel-level X-ray to near-infrared image fusion
Combining information from multispectral images into a fused image is informative and beneficial for human or machine perception. Currently, multiple photodetectors with different response bands are used, whic...
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Article
Open AccessA distinctive ligand recognition mechanism by the human vasoactive intestinal polypeptide receptor 2
Class B1 of G protein-coupled receptors (GPCRs) comprises 15 members activated by physiologically important peptide hormones. Among them, vasoactive intestinal polypeptide receptor 2 (VIP2R) is expressed in th...
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Article
Open AccessStructural insights into multiplexed pharmacological actions of tirzepatide and peptide 20 at the GIP, GLP-1 or glucagon receptors
Glucose homeostasis, regulated by glucose-dependent insulinotropic polypeptide (GIP), glucagon-like peptide-1 (GLP-1) and glucagon (GCG) is critical to human health. Several multi-targeting agonists at GIPR, G...
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Article
Open AccessMulti-year incubation experiments boost confidence in model projections of long-term soil carbon dynamics
Global soil organic carbon (SOC) stocks may decline with a warmer climate. However, model projections of changes in SOC due to climate warming depend on microbially-driven processes that are usually parameteri...
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Open AccessMore replenishment than priming loss of soil organic carbon with additional carbon input
Increases in carbon (C) inputs to soil can replenish soil organic C (SOC) through various mechanisms. However, recent studies have suggested that the increased C input can also stimulate the decomposition of o...
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Article
Open AccessThe effect of decreasing permafrost stability on ecosystem carbon in the northeastern margin of the Qinghai–Tibet Plateau
The objective of this study is to investigate the effect of decreased permafrost stability on carbon storage of the alpine ecosystems in the northeastern margin of the Qinghai–Tibet Plateau. During July and Au...
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Article
Open AccessSerum ω-3 Polyunsaturated Fatty Acids and Potential Influence Factors in Elderly Patients with Multiple Cardiovascular Risk Factors
Recent clinical trials failed to demonstrate that ω-3 polyunsaturated fatty acid (PUFA) supplement reduced cardiovascular events, which contradicted previous evidence. However, serum ω-3 PUFA concentrations of...
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Open AccessDeterminants of carbon release from the active layer and permafrost deposits on the Tibetan Plateau
The sign and magnitude of permafrost carbon (C)-climate feedback are highly uncertain due to the limited understanding of the decomposability of thawing permafrost and relevant mechanistic controls over C rele...
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Article
Open AccessDual mechanisms regulate ecosystem stability under decade-long warming and hay harvest
Past global change studies have identified changes in species diversity as a major mechanism regulating temporal stability of production, measured as the ratio of the mean to the standard deviation of communit...
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Open AccessStronger warming effects on microbial abundances in colder regions
Soil microbes play critical roles in regulating terrestrial carbon (C) cycle and its feedback to climate change. However, it is still unclear how the soil microbial community and abundance respond to future cl...