4 Result(s)

Article

Tet methylcytosine dioxygenase 2 (TET2) deficiency elicits EGFR-TKI (tyrosine kinase inhibitors) resistance in non-small cell lung cancer

Despite epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKI) have shown remarkable efficacy in patients with EGFR-mutant non-small cell lung cancer (NSCLC), acquired resistance inevitably deve...

Jian Zhang, Kejia Zhao, Wen**g Zhou, Ran Kang… in Signal Transduction and Targeted Therapy (2024)

Article

Predicting assembly mode of membraneless organelles by a FRET-based crowding sensor

Feng Chen, Siyuan Shen, Xu Cao, Liang Zhang… in Signal Transduction and Targeted Therapy (2023)

Article

miR-410 induces both epithelial–mesenchymal transition and radioresistance through activation of the PI3K/mTOR pathway in non-small cell lung cancer

Radiotherapy remains one of the major treatments for non-small cell lung cancer (NSCLC) patients; whereas intrinsic or acquired radioresistance limits its efficacy. Nevertheless, most studies so far have only ...

Yue Yuan, Hu Liao, Qiang Pu, **xian Ke… in Signal Transduction and Targeted Therapy (2020)

Article

Neurons generated from carcinoma stem cells support cancer progression

Recent evidences show that nervous system acts as a crucial part of cancer microenvironment. Infiltration of nerve fibers into cancer microenvironment has an important active role in cancer progression. The st...

Ran Lu, Chuanwen Fan, Wenqi Shangguan, Yuan Liu… in Signal Transduction and Targeted Therapy (2017)