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Article
Effect of Ball Milling Time on Microstructure and Hydrogen Storage Properties of Nd5Mg41Ni Alloy
Mg-based alloys must be dehydrogenated at high pressure and temperatures, limiting their practical application. In this paper, Nd5Mg41Ni alloy was prepared by vacuum melting, and the as-cast alloy was ball milled...
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Article
Open AccessGenetic perturbation of IL-6 receptor signaling pathway and risk of multiple respiratory diseases
Dysregulation of inflammation can lead to multiple chronic respiratory diseases, such as chronic obstructive pulmonary disease (COPD) and asthma. Interleukin-6 (IL6) is crucial in regulating the inflammatory c...
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Article
Open AccessDevelopment and validation of a machine learning-based readmission risk prediction model for non-ST elevation myocardial infarction patients after percutaneous coronary intervention
To investigate the factors that influence readmissions in patients with acute non-ST elevation myocardial infarction (NSTEMI) after percutaneous coronary intervention (PCI) by using multiple machine learning (...
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Article
Examining Intolerance of Uncertainty as a System of Interacting Beliefs: A Network Analysis Among 108,540 Adolescents
While intolerance of uncertainty (IU) is widely recognized as a transdiagnostic risk factor for psychopathology, there is limited research on its internal structure and core features. This study aimed to emplo...
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Article
Enhanced Circular Dichroism Induced by Electric and Magnetic Resonance in Nanohole with Embedded Nanorod
Circular dichroism (CD) is a significant optical response of chiral plasmonic nanostructures, with extensive applications in chiral sensing, biological detection, and negative refractive index media. In this s...
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Article
Dependency-position relation graph convolutional network with hierarchical attention mechanism for relation extraction
Existing research extensively incorporates syntactic information, especially dependency trees, to enhance the performance of relation extraction tasks. However, relying solely on dependency information may not...
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Article
Open AccessUtilizing a structure-based virtual screening approach to discover potential LSD1 inhibitors
Lysine-specific demethylase 1 (LSD1) is highly expressed in a variety of malignant tumors, rendering it a crucial epigenetic target for anti-tumor therapy. Therefore, the inhibition of LSD1 activity has emerge...
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Article
A High Efficient and Stable Copper(II) Porphyrin-Sensitized Anatase TiO2 for Tetracycline Degradation Under Visible Light
Anatase TiO2 (A-TiO2) with high specific surface area and mesoporous structure was successfully obtained by the solvothermal method. The decoration effects of copper(II) porphyrins on the morphology, structural a...
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Article
The environmental impact assessment of China’s ecological migration from a social–ecological perspective
When accounting for the social–ecological impact of an ecological restoration program, both objective environmental contexts and people’s subjective perceptions are required. While this kind of environmental i...
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Article
Classic Famous Prescription Kai-**n-San Ameliorates Alzheimer’s Disease via the Wnt/β-Catenin Signaling Pathway
Kai-**n-San (KXS) is a classic famous prescription composed of Polygalae Radix, Ginseng Radix et Rhizoma, Acori Tatarinowii Rhizoma, and Poria. Clinically, KXS is effective in treating amnesia and regulating c...
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Article
Open AccessChina’s safe and just space during 40 years of rapid urbanization and changing policies
China’s high-speed economic development was accompanied by rapid urbanization for forty years, guided by a series of changing policies enacted by the central government. However, did China become more sustaina...
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Article
Open AccessNEAT1_1 confers gefitinib resistance in lung adenocarcinoma through promoting AKR1C1-mediated ferroptosis defence
Gefitinib is one of the most extensively utilized epidermal growth factor receptor-tyrosine kinase inhibitors (EGFR-TKIs) for treating advanced lung adenocarcinoma (LUAD) patients harboring EGFR mutation. Howe...
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Article
Open AccessTet methylcytosine dioxygenase 2 (TET2) deficiency elicits EGFR-TKI (tyrosine kinase inhibitors) resistance in non-small cell lung cancer
Despite epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKI) have shown remarkable efficacy in patients with EGFR-mutant non-small cell lung cancer (NSCLC), acquired resistance inevitably deve...
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Article
Open AccessSpatio-temporal changes and hydrological forces of wetland landscape pattern in the Yellow River Delta during 1986–2022
Estuarine wetlands provide valuable ecosystem services, but 20–78% of coastal wetlands are facing the risk of loss by the end of the century. The Yellow River Delta (YRD) wetland, one of the most productive de...
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Article
Open AccessThe relationship between childhood socioeconomic status and depression level in older adults: the mediating role of adult socioeconomic status and subjective well-being
There is a causal link between childhood socioeconomic status and health status in adulthood and beyond. It's vital to comprehend the relationship between childhood socioeconomic status and mental health among...
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Article
The F-box protein ZmFBL41 negatively regulates disease resistance to Rhizoctonia solani by degrading the abscisic acid synthase ZmNCED6 in maize
The maize F-box protein ZmFBL41 targets abscisic acid synthase 9-cis-epoxycarotenoid dioxygenase 6 for degradation, and this regulatory module is exploited by Rhizoctonia solani to promote infection.
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Article
Open AccessAkkermansia muciniphila Improves Depressive-Like Symptoms by Modulating the Level of 5-HT Neurotransmitters in the Gut and Brain of Mice
Accumulating evidence has suggested that the gut microbiome plays an important role in depression. Akkermansia muciniphila (AKK), a next-generation probiotic, shows a beneficial effect on immune and metabolic hom...
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Article
Open AccessScarcity and quality risks for future global urban water supply
Supply of freshwater to the world’s cities is increasingly affected by human pressures and climate change. Understanding the effects of human pressures and climate change on global urban water scarcity and qua...
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Article
Open AccessPerioperative outcomes of uniportal versus three-port video-assisted thoracoscopic surgery in lung cancer patients aged ≥ 75 years old: a cohort study
Increasing attention has been raised on the surgical option for lung cancer patients aged ≥75 years, however, few studies have focused on whether uniportal video-assisted thoracoscopic surgery (VATS) is safe a...
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Article
Open AccessSerious underestimation of reduced carbon uptake due to vegetation compound droughts
Compound droughts with low soil moisture (SM) and high vapor pressure deficit (VPD) pose significant threats to terrestrial carbon sink and agricultural production. However, the frequency and intensity of comp...
