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Article
Open AccessComparison between MRI-negative and positive results and the predictors for a poor prognosis in patients with idiopathic acute transverse myelitis
Idiopathic acute transverse myelitis (IATM) is a focal inflammatory disorder of the spinal cord that results in motor, sensory, and autonomic dysfunction. However, the comparative analysis of MRI-negative and ...
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Article
SIRT2 as a Potential Biomarker in Lung Adenocarcinoma: Implications for Immune Infiltration
SIRT2 play important roles in cell cycle and cellular metabolism in the development of non-small cell lung cancer (NSCLC), and SIRT2 exhibits its therapeutic effect on NSCLC tumors with high expression of SIRT...
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Article
Open AccessAn in-vitro three-dimensional surgical simulation technique to predict tibial tunnel length in transtibial posterior cruciate ligament reconstruction
During the transtibial posterior cruciate ligament (PCL) reconstruction, drilling depth excessively longer than the tibial tunnel length (TTL) is an important reason to cause popliteal neurovascular bundle inj...
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Article
Open AccessYY1 mediated DCUN1D5 transcriptional activation promotes triple-negative breast cancer progression by targeting FN1/PI3K/AKT pathway
Triple-negative breast cancer (TNBC) is more aggressive and has a higher metastasis rate compared with other subtypes of breast cancer. Due to the lack of drug-targetable receptors, chemotherapy is now the onl...
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Article
Open AccessStability in change: building a stable ecological security pattern in Northeast China under climate and land use changes
Climate change and land use change caused by human activities have a profound impact on ecological security. Simulating the spatio-temporal changes in ecosystem service value and ecological security patterns u...
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Article
A new perspective on the autophagic and non-autophagic functions of the GABARAP protein family: a potential therapeutic target for human diseases
Mammalian autophagy-related protein Atg8, including the LC3 subfamily and GABARAP subfamily. Atg8 proteins play a vital role in autophagy initiation, autophagosome formation and transport, and autophagy-lysoso...
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Article
Studying on genetic diversity and metabolic differences of Saccharomyces cerevisiae in Baijiu
Baijiu (a Chinese liquor), one of the six world-renowned distilled liquors, is popular among consumers, and Saccharomyces cerevisiae plays the most important role. However, the diversity and metabolic differences...
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Article
Open AccessHydrogen gas inhalation ameliorates LPS-induced BPD by inhibiting inflammation via regulating the TLR4–NFκB–IL6/NLRP3 signaling pathway in the placenta
Hydrogen (H2) is regarded as a novel therapeutic agent against several diseases owing to its inherent biosafety. Bronchopulmonary dysplasia (BPD) has been widely considered among adverse pregnancy outcomes, witho...
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Article
Pioglitazone Antagonized the Effects of Advanced Glycation End Products on Achilles Tendon Healing and Improved the Recovery of Tendon Biomechanical Properties
Advanced glycation end products (AGEs) often accumulate in the Achilles tendon during the course of diabetes. This study aims to determine the impact of AGEs on tendon repair and explore the role of pioglitazo...
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Article
Functions and targets of miRNAs in pharmacological and toxicological effects of major components of Tripterygium wilfordii Hook F
Tripterygium wilfordii Hook F (TwHF) has a long history of use as a traditional Chinese medicine and has been widely administered to treat various inflammatory and autoimmune diseases. MicroRNAs (miRNAs) are end...
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Article
Enhancing the efficiency and longevity of inverted perovskite solar cells with antimony-doped tin oxides
Inverted perovskite solar cells possess great potential for single or multi-junction photovoltaics. However, energy and charge losses at the interfaces limit their performance. Here we introduce p-type antimon...
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Article
Open AccessNatural lipid nanoparticles extracted from Morus nigra L. leaves for targeted treatment of hepatocellular carcinoma via the oral route
The clinical application of conventional medications for hepatocellular carcinoma treatment has been severely restricted by their adverse effects and unsatisfactory therapeutic effectiveness. Inspired by the c...
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Chapter and Conference Paper
Research on the Application of Management Decision Prediction Based on Machine Learning in Education System
Making good educational management decisions is essential for the development of the education system and the growth of students. Educational management decisions can help educational institutions better under...
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Chapter and Conference Paper
Reverse Multidimensional Auction Based Vehicle Selection and Resource Allocation for IoV
Federated Learning (FL) is gaining popularity in the Internet of Vehicles (IoV), which has led to a rise in demand for high-quality communication and computation resources. To address the communication and com...
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Article
Open AccessDiurnal switches in diazotrophic lifestyle increase nitrogen contribution to cereals
Uncoupling of biological nitrogen fixation from ammonia assimilation is a prerequisite step for engineering ammonia excretion and improvement of plant-associative nitrogen fixation. In this study, we have iden...
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Article
Develo** a design thinking engagement scale for early childhood teachers
Engaging in design thinking activities has been increasingly viewed as important for the craft of teaching for early childhood practitioners. However, reliable and valid measurements for this are lacking. As s...
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Article
Open AccessAssociation between light rare earth elements in maternal plasma and the risk of spontaneous preterm birth: a nested case-control study from the Bei**g birth cohort study
Parental exposure to rare earth elements (REEs) could increase the risk of premature rupture of membranes, a major cause of spontaneous preterm birth (SPB). In addition, different subtypes of SPB, such as spon...
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Article
Open AccessBeat-wise segmentation of electrocardiogram using adaptive windowing and deep neural network
Timely detection of anomalies and automatic interpretation of an electrocardiogram (ECG) play a crucial role in many healthcare applications, such as patient monitoring and post treatments. Beat-wise segmentat...
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Article
Open AccessThe retrospective data analysis on the pedigree of nervous system diseases in children
Nowadays, the development of diagnosis and treatment technology is constantly changing the pedigree and classification of nervous system diseases. Analyzing changes in earlier disease pedigrees can help us und...
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Article
Open AccessImpact of body mass index in therapeutic response for HER2 positive breast cancer treated with neoadjuvant targeted therapy: a multi-center study and meta-analysis
While overweight/obesity has become a major public health issue worldwide, any association between body mass index (BMI) and therapeutic response in neoadjuvant targeted therapy treated HER2 positive breast ca...
