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Article
Mechanical Property and Fracture Behavior of Borazine-Derived Bulk Boron Nitride Ceramics Reinforced with Chopped Si3N4 Fiber
Boron nitride (BN) ceramics are promising high-temperature structural and functional materials. Bulk BN ceramics are difficult to fabricate due to the covalent bond and flake grain structure. Polymer-derived c...
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Article
Open AccessCrosstalk between m6A modification and autophagy in cancer
Autophagy is a cellular self-degradation process that plays a crucial role in maintaining metabolic functions in cells and organisms. Dysfunctional autophagy has been linked to various diseases, including canc...
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Article
Open AccessOptimal cutoff value of the dry eye-related quality-of-life score for diagnosing dry eye disease
This retrospective study aimed to determine the optimal cutoff values of the Dry Eye-Related Quality-of-Life Score (DEQS) questionnaire for diagnosing dry eye disease (DED) and classifying DED severities. Part...
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Article
Open AccessCorrection: Knockdown of ubiquitin-like modifier-activating enzyme 2 promotes apoptosis of clear cell renal cell carcinoma cells
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Article
Open AccessThe role of the methyltransferase METTL3 in prostate cancer: a potential therapeutic target
The incidence of prostate cancer (PCa), the most prevalent malignancy, is currently at the forefront. RNA modification is a subfield of the booming field of epigenetics. To date, more than 170 types of RNA mod...
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Article
Open AccessThe role of RNA modification in urological cancers: mechanisms and clinical potential
RNA modification is a post-transcriptional level of regulation that is widely distributed in all types of RNAs, including mRNA, tRNA, rRNA, miRNA, and lncRNA, where N6-methyladenine (m6A) is the most abundant mRN...
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Article
Aspartate all-in-one do** strategy enables efficient all-perovskite tandems
All-perovskite tandem solar cells hold great promise in surpassing the Shockley–Queisser limit for single-junction solar cells1–3. However, the practical use of these cells is currently hampered by the subpar per...
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Article
Study of CO molecules on Pd/Al2O3/NiAl(110) surface by atomic force microscopy and Kelvin probe force microscopy
Reactant adsorption sites of novel metal catalysts are difficult to characterize precisely, which is vital for understanding heterogeneous reactions and designing efficient catalytic systems. However, even at ...
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Article
Open AccessEmerging applications of extracellular vesicles in tumor therapy
Extracellular vesicles (EVs) have tremendous potential as nano/micron-sized drug delivery carriers. Their physical, chemical and biological characteristics distinguish them as unique carriers with specific ph...
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Article
Open AccessLower SLC7A2 expression is associated with enhanced multidrug resistance, less immune infiltrates and worse prognosis of NSCLC
Solute carrier family 7 member 2 (SLC7A2), a cationic amino acid transporter, is lowly expressed in ovarian and hepatocellular cancers, which is associated with their worse prognosis. However, its roles in the...
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Article
Venetoclax alone or in combination with other regimens treatment achieve deep and sustained remission of relapsed/refractory chronic lymphocytic leukemia: a meta-analysis
Recently, the use of novel targeted drugs significantly improved the overall response rate (ORR) and survival of patients with relapsed/refractory chronic lymphocytic leukemia (R/R CLL). The treatment of R/R C...
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Article
Open AccessKnockdown of ubiquitin-like modifier-activating enzyme 2 promotes apoptosis of clear cell renal cell carcinoma cells
Small ubiquitin-related modifier (SUMO) proteins are involved in the development of tumors. Ubiquitin-like modifier-activating enzyme 2 (UBA2) is an important member of the SUMO modification system; however, i...
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Article
Raman spectroscopy analysis of the effect of electrolysis treatment on the structure of soy protein isolate
The effect of electrolysis on soy protein isolate (SPI) was studied by Raman spectroscopy and ultraviolet spectroscopy. The results showed that with the prolongation of electrolysis time, the α-helix content d...
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Article
Gel-Casting Prepared Porous Si3N4 Ceramics with Different Contents of Y2O3 and Al2O3 Additives
Porous Si3N4 ceramics were prepared via a controlled gel-casting process followed by gas pressure sintering with 8 wt.% Y2O3 and Al2O3 additives. The gel-casting parameters including slurry pH value, AM: MBAM rat...
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Article
Open AccessIsothermal confined pyrolysis on source rock and kerogens in the presence and absence of water: Implication in isotopic rollover in shale gases
Isotopic rollover refers to that δ13C value of a gas component decreases with maturity. Its occurrence is closely related to high productivity of shale gas. Isothermal confined pyrolysis experiments (gold capsule...
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Article
Diagnosis of coronary artery disease in patients with atrial fibrillation using low tube voltage coronary CT angiography with isotonic low-concentration contrast agent
This prospective study evaluated the image quality and accuracy of coronary computed tomography angiography (CCTA) for diagnosing coronary artery disease (CAD) in patients with atrial fibrillation (AF), in whi...
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Article
Open AccessTargeting MC1R depalmitoylation to prevent melanomagenesis in redheads
Some genetic melanocortin-1 receptor (MC1R) variants responsible for human red hair color (RHC-variants) are consequently associated with increased melanoma risk. Although MC1R signaling is critically dependen...
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Article
Open AccessPrevalence and clinical characteristics of dry eye disease in community-based type 2 diabetic patients: the Beixin**g eye study
This study was performed to evaluate the prevalence and clinical characteristics of dry eye disease (DED) in community-based type 2 diabetic patients and to identify the associated factors related with DED.
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Article
Open AccessRadix Puerariae and Fructus Crataegi mixture inhibits renal injury in type 2 diabetes via decreasing of AKT/PI3K
Radix puerariae (RP) is a herbal medicines for diabetes, mainly because of anti-oxidative, insulin resistance and hypoglycemic effect. Fructus crataegi (FC) also possesses strong antioxidant activity in vitro....
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Article
Single and double over-barrier ionization of He, He+ and Ne system by positron impact
The classical over-barrier ionization model (COBI) method and trajectory calculations were utilized to simulate the ionization of He+ impacted by a positron. The calculated ionization cross sections of He+ agree...
