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Article
Phase separation-competent FBL promotes early pre-rRNA processing and translation in acute myeloid leukaemia
RNA-binding proteins (RBPs) are pivotal in acute myeloid leukaemia (AML), a lethal disease. Although specific phase separation-competent RBPs are recognized in AML, the effect of their condensate formation on ...
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Article
Open AccessStructural characteristics of gut microbiota in longevity from Changshou town, Hubei, China
The gut microbiota (GM) and its potential functions play a crucial role in maintaining host health and longevity. The aim of this study was to investigate the potential relationship between GM and longevity. W...
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Article
Responding of zooplankton to environmental factor changes in the Changjiang River estuarine regions in spring-summer from 2016 to 2020
The estuarine areas are under frequent influence from freshwater intrusion and ocean currents, in which zooplankton species are diversified and variable as they are sensitive to physio-chemical variations in w...
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Article
Open AccessPhysiological effects of resistant starch and its applications in food: a review
Starch,as the main source of carbohydrates in the diet, provides energy for various activities of the body. Different types and structures of starch lead to variations in digestion and absorption, thereby affe...
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Article
Relationship Between Mycotoxin Production and Gene Expression in Fusarium graminearum Species Complex Strains Under Various Environmental Conditions
The Fusarium graminearum species complex (FGSC) can produce various mycotoxins and is a major concern for food quantity and quality worldwide. In this study, we determined the effects of water activity (aw), temp...
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Article
Open AccessPreventive and therapeutic benefits of nelfinavir in rhesus macaques and human beings infected with SARS-CoV-2
Effective drugs with broad spectrum safety profile to all people are highly expected to combat COVID-19 caused by SARS-CoV-2. Here we report that nelfinavir, an FDA approved drug for the treatment of HIV infec...
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Article
The association of IL-33 and systemic sclerosis: a systematic review and meta-analysis
A meta-analysis of the association between IL-33 and these diseases is lacking, and we aimed to perform a meta-analysis of the association between IL-33 and systemic sclerosis (SSc). We searched relevant paper...
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Article
A Global Meta-analysis Reveals that Nitrogen Addition Alters Plant Nutrient Concentration and Resorption in Grassland Ecosystems
Knowledge of plant nutrient strategies is crucial for defining and predicting the patterns and mechanisms resulting from nitrogen (N) deposition. However, the impacts of N enrichment on plant nutrient strategi...
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Article
RNF2 mediates pulmonary fibroblasts activation and proliferation by regulating mTOR and p16-CDK4-Rb1 signaling pathway
Pulmonary fibrosis (PF) is a chronic, progressive interstitial lung disease with unknown etiology, associated with increasing morbidity and pessimistic prognosis. Pulmonary fibroblasts (PFbs) are the key effec...
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Article
Open AccessSARS-CoV-2 N protein potentiates host NPM1-snoRNA translation machinery to enhance viral replication
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Article
Animal models of drug-induced pulmonary fibrosis: an overview of molecular mechanisms and characteristics
Idiopathic pulmonary fibrosis (IPF) is a progressive interstitial lung disease characterized by progressive loss of pulmonary function. Drug-induced interstitial lung disease has been reported as a severe adve...
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Article
Nutrient addition and warming alter the soil phosphorus cycle in grasslands: A global meta-analysis
Grasslands are the most extensive vegetation type in the terrestrial ecosystem and have an important role in the soil phosphorus (P) cycle. Many nutrient addition and warming experiments have been conducted in...
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Article
Unusual global outbreak of monkeypox: what should we do?
Recently, monkeypox has become a global concern amid the ongoing COVID-19 pandemic. Monkeypox is an acute rash zoonosis caused by the monkeypox virus, which was previously concentrated in Africa. The re-emerge...
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Article
Flexural Performance of Composite Beams Using High-Strength Steel and High-Strength Concrete
The composite beams having high-strength steel (HSS) and high-strength concrete (HSC) can fully exploit the mechanical behavior of both materials. However, the published research on the structural behavior of ...
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Article
Open AccessThe antioxidant methyl gallate inhibits fungal growth and deoxynivalenol production in Fusarium graminearum
Production of the Fusarium toxin deoxynivalenol (DON) is associated with oxidative stress and has been indicated to be part of an adaptive response to oxidative stress in the important wheat fungus Fusarium grami...
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Article
Correction to: Surface-imprinted β-cyclodextrin-functionalized carbon nitride nanosheets for fluorometric determination of sterigmatocystin
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Article
Effects of Cracks on the Mass Transfer of Polymer Electrolyte Membrane Fuel Cell with High Performance Membrane Electrode Assembly
A two-dimensional geometric model is developed for a polymer electrolyte based on the liquid water penetration mechanism in the membrane electrode assemblies under the action of capillary pressure. The effects...
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Article
Open Accesshsa_circ_001946 elevates HOXA10 expression and promotes the development of endometrial receptivity via sponging miR-135b
Impaired endometrial receptivity is a major reason for embryo implantation failure. There’s a paucity of information regarding the role of circRNAs on endometrial receptivity. Here, we investigated the functio...
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Article
Open AccessRational development of a human antibody cocktail that deploys multiple functions to confer Pan-SARS-CoVs protection
Structural principles underlying the composition and synergistic mechanisms of protective monoclonal antibody cocktails are poorly defined. Here, we exploited antibody cooperativity to develop a therapeutic an...
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Chapter and Conference Paper
UAV-Assisted Wireless Communication Network Capacity Analysis and Deployment Decision
Deploying the unmanned aerial vehicle (UAV) as an aerial base station to establish or assist wireless communication networks is a promising technology. However, there are also some significant challenges invol...