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  1. No Access

    Article

    Transcriptome sequencing identifies novel EVX fusions involved in transcriptional activation of HOX family genes in pediatric immature T-cell acute lymphoblastic leukemia: two cases reports and a literature review

    Driver genomic alterations in pediatric immature T-cell acute lymphoblastic leukemia are not fully known. We report two cases of novel EVX fusions involved in the transcriptional activation of HOX family genes, E...

    **ao Zhang, Bowen Cui, Yizhen Li, Zhiheng Li… in International Journal of Hematology (2023)

  2. Article

    Open Access

    LMO2 promotes the development of AML through interaction with transcription co-regulator LDB1

    One of the characteristics of leukemia is that it contains multiple rearrangements of signal transduction genes and overexpression of non-mutant genes, such as transcription factors. As an important regulator ...

    Lihui Lu, Jianwei Wang, Fang Fang, Ailian Guo, Shuting Jiang… in Cell Death & Disease (2023)

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  3. Article

    Open Access

    Maternal effects drive intestinal development beginning in the embryonic period on the basis of maternal immune and microbial transfer in chickens

    Nutrition drives immunity and health in animals, and maternal immunity benefits offspring. In our previous study, a nutritional intervention strategy was found to promote the immunity of hens, which subsequent...

    Haizhou Gong, Tai** Wang, Min Wu, Qianran Chu, Hainan Lan, Wuying Lang… in Microbiome (2023)

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  4. No Access

    Chapter and Conference Paper

    Commuting Mode Choices in Small Cities of China: A Case Study of Qianshan

    As the size of cities grows with socio-economic development, the corresponding commuting patterns become more and more abundant. However, as there is a wide gap between large and small cities, inverting their ...

    Tianran Chu in Proceedings of the 6th International Confe… (2023)

  5. Article

    Open Access

    BRD4 PROTAC degrader ARV-825 inhibits T-cell acute lymphoblastic leukemia by targeting 'Undruggable' Myc-pathway genes

    T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive disease with a high risk of induction failure and poor outcomes, with relapse due to drug resistance. Recent studies show that bromodomains and extr...

    Shuiyan Wu, You Jiang, Yi Hong, **nran Chu, Zimu Zhang… in Cancer Cell International (2021)

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  6. No Access

    Chapter

    The Role of Translation Played in the Evolution of Mandarin: A Corpus-based Account

    This chapter begins with an overview of the studies on translational Chinese over the past decades in China. Traditionally, translation studies would take translational language as a source of examples for th...

    Hongwu Qin, Lei Kong, Ranran Chu in Corpus-based Translation and Interpreting … (2020)

  7. No Access

    Article

    A rapid and efficient polyethylenimine-based transfection method to prepare lentiviral or retroviral vectors: useful for making iPS cells and transduction of primary cells

    To improve the efficiency, reproducibility and consistency of the PEI-based transfection method that is often used in preparation of recombinant lentiviral or retroviral vectors.

    Shaozhe Yang, Haijun Shi, **nran Chu, **aoling Zhou, **nan Sun in Biotechnology Letters (2016)