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Article

Extrachromosomal circular DNA in colorectal cancer: biogenesis, function and potential as therapeutic target

Extrachromosomal circular DNA (ecDNA) has gained renewed interest since its discovery more than half a century ago, emerging as critical driver of tumor evolution. ecDNA is highly prevalent in many types of ca...

Yinnan Chen, Quanpeng Qiu, Junjun She, Jun Yu in Oncogene (2023)