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Article
Open AccessClinicopathologic and prognostic significance of tumor-associated macrophages in cervical cancer: a systematic review and meta-analysis
The role of tumor-associated macrophages (TAMs) in cervical cancer (CC) remains controversial. Here, we report a meta-analysis of the association between TAMs infiltration and clinical outcomes.
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Article
Nutrient-rich sediment promotes, while fertile water inhibits the growth of the submerged macrophyte Vallisneria denseserrulata: implications for shallow lake restoration
Submerged macrophytes are crucial for the restoration of shallow eutrophic lake but they are diminished in coverage or lost with eutrophication. Their recovery after nutrient loading reduction depends on water...
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Article
Open AccessOncological outcomes of fertility-sparing surgery versus radical surgery in stage - epithelial ovarian cancer: a systematic review and meta-analysis
The oncological outcomes of fertility-sparing surgery (FSS) compared to radical surgery (RS) in patients with stage I epithelial ovarian cancer (EOC) remain a subject of debate. We evaluated the risk ratios (R...
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Article
Transcriptomic Responses and Larval-Stage Growth of Protandrous Yellowfin Seabream (Acanthopagrus Latus) to Different Polyethylene Microplastics Exposure
Polyethylene microplastics (PE-MPs) were widespread in the marine environment; thus, their influences on marine hermaphroditic fish cannot be ignored. This study intends to evaluate the adverse biological effe...
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Article
Open AccessExploring the therapeutic mechanisms of Coptidis Rhizoma in gastric precancerous lesions: a network pharmacology approach
Gastric precancerous lesions are a critical stage in the development of gastric cancer or gastric adenocarcinoma, and their outcome plays an important role in the malignant progression of gastric cancer. Copti...
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Article
Direct abdominal vein thrombus imaging (DATI): a contrast-free black-blood MR technique for the diagnosis of abdominal vein thrombosis
To develop and evaluate a direct abdominal vein thrombus imaging (DATI) technique, based on a respiratory navigating SPACE sequence with DANTE black-blood preparation, for diagnosing abdominal vein thrombosis ...
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Article
Open AccessPanax notoginseng saponins prevent dementia and oxidative stress in brains of SAMP8 mice by enhancing mitophagy
Mitochondrial dysfunction is one of the distinctive features of neurons in patients with Alzheimer’s disease (AD). Intraneuronal autophagosomes selectively phagocytose and degrade the damaged mitochondria, mit...
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Article
Open AccessCircRNA ITCH Inhibits Epithelial–Mesenchymal Transformation and Promotes Apoptosis in Papillary Thyroid Carcinoma via miR-106a-5p/JAZF1 Axis
Circular RNA ITCH (circ-ITCH) is implicated in papillary thyroid carcinoma (PTC) development. Nevertheless, the more detailed molecular mechanism remains uncovered. The transcriptional level of circ-ITCH was t...
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Article
Open AccessEfficacy and safety of mesenchymal stem cells in patients with acute ischemic stroke: a meta-analysis
This meta-analysis and systematic review were conducted to comprehensively evaluate the efficacy and safety of mesenchymal stem cells in patients with acute ischemic stroke.
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Article
Open AccessGlobal fine-resolution data on springtail abundance and community structure
Springtails (Collembola) inhabit soils from the Arctic to the Antarctic and comprise an estimated ~32% of all terrestrial arthropods on Earth. Here, we present a global, spatially-explicit database on springta...
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Chapter and Conference Paper
Imputation of Compound Property Assay Data Using a Gene Expression Programming-Based Method
Compound property assays are an important part of drug development, but incomplete data may occur for a variety of reasons. To deal with these incomplete data and improve the success rate of drug development, ...
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Chapter and Conference Paper
T-GraphDTA: A Drug-Target Binding Affinity Prediction Framework Based on Protein Pre-training Model and Hybrid Graph Neural Network
Drug-target affinity (DTA) prediction is an important task in computer-aided drug design and drug repositioning, which can speed up drug development and reduce resource consumption. Researchers have explored s...
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Article
The Relative Importance of Coarse-Scale Climate and Fine-Scale Nitrogen Availability Contrasts in Driving Home-Field Advantage Effects in Litter Decomposition
Understanding the relative importance of climates at coarse scales and nitrogen (N) availability at fine scales in driving litter decomposition is crucial for ecosystem functioning. In this study, we explored ...
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Article
Silver nanoparticles deposited carbon microspheres nanozyme with enhanced peroxidase-like catalysis for colorimetric detection of Hg2+ in seafood
Novel methods for high-performance detection of Hg2+ in seafood are critical for ensuring food safety and human health. Herein, Ag nanoparticles (Ag NPs) were successfully deposited on carbon microspheres (CMs) t...
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Article
Human activities and species biological traits drive the long-term persistence of old trees in human-dominated landscapes
Old trees have many ecological and socio-cultural values. However, knowledge of the factors influencing their long-term persistence in human-dominated landscapes is limited. Here, using an extensive database (...
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Article
Open AccessMODILM: towards better complex diseases classification using a novel multi-omics data integration learning model
Accurately classifying complex diseases is crucial for diagnosis and personalized treatment. Integrating multi-omics data has been demonstrated to enhance the accuracy of analyzing and classifying complex dise...
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Article
Open AccessSeasonal and daily variations in the occurence and outcomes of acute Stanford type A dissections: a retrospective single-center study
To investigate the seasonal, monthly, and daily distributions of the incidence of Stanford type-A acute aortic dissection (TAAAD) and identify seasonality in the duration of hospital stay and in-hospital morta...
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Article
Open AccessGlobally invariant metabolism but density-diversity mismatch in springtails
Soil life supports the functioning and biodiversity of terrestrial ecosystems. Springtails (Collembola) are among the most abundant soil arthropods regulating soil fertility and flow of energy through above- a...
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Chapter and Conference Paper
Building Fall Safety Early Warning System Based on Directed Weighted Network
Directed Weighted Network (DWN) are ubiquitous in nature. It is of great practical significance to evaluate and analyze the importance of their nodes. With the continuous maturity of the network research field...
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Article
Geographic Scale Influences the Interactivities Between Determinism and Stochasticity in the Assembly of Sedimentary Microbial Communities on the South China Sea Shelf
Determinism and stochasticity in microbial community composition decisions have attracted wide attention. However, there is no consensus on their interrelationships and relative importance, and the mechanism c...
