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Article
Comprehensive Insights into the Health Effects of Selenium Exposure and Supplementation Among the Chinese Community Middle-Aged and Elderly: a Combined Retrospective Cohort Study and Intervention Study
Selenium (Se) is an essential trace element for maintaining human health, for example, plays a crucial role in preventing aging-related diseases. However, most studies on the health effects of Se among the com...
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Article
Kinect-based objective assessment of the acute levodopa challenge test in parkinsonism: a feasibility study
The acute levodopa challenge test (ALCT) is an important and valuable examination but there are still some shortcomings with it. We aimed to objectively assess ALCT based on a depth camera and filter out the b...
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Article
Early-onset and late-onset Parkinson’s disease exhibit a different profile of gait and posture features based on the Kinect
Gait and posture abnormalities are the common disabling motor symptoms in Parkinson's disease (PD). This study aims to investigate the differential characteristics of gait and posture in early-onset PD (EOPD) ...
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Article
Kinect-based objective assessment for early frailty identification in patients with Parkinson’s disease
Frailty is common in Parkinson’s disease (PD) and increases vulnerability to adverse outcomes. Early detection of this syndrome aids in early intervention.
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Article
Open AccessA de novo mutation of ADAMTS8 in a patient with Wiedemann–Steiner syndrome
Wiedemann–Steiner syndrome (WDSTS) is a rare autosomal dominant disorder caused by mutations in the KMT2A gene and is usually characterized by hairy elbows, short stature, developmental delay, intellectual disabi...
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Article
Open AccessWhole-genome sequencing reveals adaptations of hairy-footed jerboas (Dipus, Dipodidae) to diverse desert environments
Environmental conditions vary among deserts across the world, spanning from hyper-arid to high-elevation deserts. However, prior genomic studies on desert adaptation have focused on desert and non-desert compa...
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Article
Study on the amplification effect and law of soil depth on ground motion
To analyze the relationship between ground motion and different soil depth and effectively reduce the damage degree of ground motion, the amplification effect and law of soil depth on ground motion are studied...
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Article
Open AccessSimilar adaptative mechanism but divergent demographic history of four sympatric desert rodents in Eurasian inland
Phenotypes associated with metabolism and water retention are thought to be key to the adaptation of desert species. However, knowledge on the genetic changes and selective regimes on the similar and divergent...
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Article
Open AccessChanges of T lymphocyte subpopulations and their roles in predicting the risk of Parkinson’s disease
T lymphocytes are involved in the pathogenesis of Parkinson’s disease (PD), while the heterogeneity of T-cell subpopulations remains elusive. In this study, we analyzed up to 22 subpopulations of T lymphocytes...
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Article
Open AccessA summary index derived from Kinect to evaluate postural abnormalities severity in Parkinson’s Disease patients
Postural abnormalities are common disabling motor complications affecting patients with Parkinson’s disease (PD). We proposed a summary index for postural abnormalities (IPA) based on Kinect depth camera and e...
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Article
Industrial agglomeration and carbon neutrality in China: lessons and evidence
This study explored the impact of industrial agglomeration on carbon neutrality and its spatial spillover effects utilizing the expanded the output density theoretical model of Ciccone and Hall. The main findi...
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Chapter and Conference Paper
Construction of Smart Health Management Mode—Exploration and Practice of Physical Education Researchers of Tsinghua University
Rapid development of information technology and medical technology provides a new way for health management and plays an important role in optimizing the whole process of health management. Based on health man...
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Chapter and Conference Paper
Types of Safety Risks of Sports Training for Children and Thoughts of Management—A Case Study Analysis Based on H Training Institution in Huaihua City
This paper uses field research, case analysis, and other methods to analyze the current situation of children’s sports training safety risks and makes a more in-depth theoretical discussion on the common safet...
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Chapter and Conference Paper
Analysis of Operation Strategies of the New Type Sharing Gymnasiums from the Perspective of Sharing Economy
Sharing gymnasium is a new type of gymnasium which provides fitness services for consumers with the help of Internet technology, intelligent devices and third-party payment platform. Taking “Health 2030” natio...
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Article
Open AccessAutomated and accurate assessment for postural abnormalities in patients with Parkinson’s disease based on Kinect and machine learning
Automated and accurate assessment for postural abnormalities is necessary to monitor the clinical progress of Parkinson’s disease (PD). The combination of depth camera and machine learning makes this purpose p...
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Article
Comparative Genomics and Molecular Analysis of Epidermophyton floccosum
Epidermophyton floccosum is one of the most common agents of human superficial fungal infections, compared with genus Trichophyton and Microsporum, it possesses uniqueness in ecology traits and rarely causing hai...
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Article
Open AccessA novel protein encoded by circFNDC3B inhibits tumor progression and EMT through regulating Snail in colon cancer
Colon cancer (CC) is a common malignant cancer. Recently, circFNDC3B was found to exert biological function in multiple cancers. However, it was unclear whether the potential protein encoded by circFNDC3B is i...
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Article
Difference in glucose tolerance between phytophagous and insectivorous bats
Bats are mostly insectivorous or phytophagous. It is hypothesized that bats are evolved from small insectivorous mammals. Therefore, the digestive and metabolic systems of phytophagous and insectivorous bats m...
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Article
Selection and identification of novel peptides specifically targeting human cervical cancer
Cervical cancer is the second most commonly diagnosed cancer and the third leading cause of cancer deaths among females in underdeveloped countries. This study aimed to identify several novel cervical cancer-s...
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Article
Investigation on three-roller cylindrical bending of 2060-T8 Al-Li alloy plate for aircraft fuselage skin components
The aluminum-lithium alloy 2060-T8 is widely utilized in the fabrication of future aircrafts. With the application of this high-strength alloy, the severe shape variation after unloading has been challenging t...
