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Article
Open AccessImmune cell landscapes are associated with high-grade serous ovarian cancer survival
High-grade serous ovarian cancer (HGSOC) is an aggressive disease known to develop resistance to chemotherapy. We investigated the prognostic significance of tumor cell states and potential mechanisms underlyi...
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Article
Coating effect of Al2O3 on ZnMn2O4 anode surface for lithium-ion batteries
Zinc manganese oxide (ZnMn2O4), exhibiting a clustered spherical structure, is synthesized using a low-temperature coprecipitation method. Following this, a coating of nano-sized Al2O3 is applied via a wet chemic...
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Article
The effects of canopy gaps on soil nutrient properties: a meta-analysis
Canopy gaps are a prevalent disturbance form in forest ecosystems that promote forest regeneration and succession by modifying the heterogeneity of the microenvironment. However, a significant knowledge gap ex...
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Article
Species selective concentration and determination of nano-selenium and inorganic selenium species in environmental waters by micropore membrane filtration and ICP-MS
Accurate quantification of nano-selenium (nSe) and other ionic Se species in aquatic environments is a prerequisite for reliable estimation of their potential hazards. In this study, a micropore membrane filtr...
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Article
Optimization of process parameters for minimizing the temperature field of high-speed milling of titanium alloy thin-walled parts
The high milling temperature in the high-speed milling process restricts the production efficiency and processing quality of titanium alloy thin-walled parts. Optimizing the processing parameters can control t...
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Article
Open AccessNanoplastics causes heart aging/myocardial cell senescence through the Ca2+/mtDNA/cGAS-STING signaling cascade
Nanoplastics (NPs) are now a new class of pollutants widely present in the soil, atmosphere, freshwater and marine environments. Nanoplastics can rapidly penetrate cell membranes and accumulate in human tissue...
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Article
Open AccessSynergistic antitumor activity between HER2 antibody-drug conjugate and chemotherapy for treating advanced colorectal cancer
Colorectal cancer (CRC) is the third most common cancer associated with a poor prognosis. Effective targeted therapy alone or in combination for treating advanced CRC remains to be a major clinical challenge. ...
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Article
Spatiotemporal dynamics of dissolved organic matter and disinfection by-products formation potential of Shengzhong Lake in southwest China
The quality and quantity of dissolved organic matter (DOM) in lakes as well as its environmental effects associated with the unintended disinfection by-products (DBPs) have received continuous attention. This ...
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Article
Open AccessExploring the impact of PEGylation on pharmacokinetics: a size-dependent effect of polyethylene glycol on prostate-specific membrane antigen inhibitors
Prostate cancer is the second most frequent cancer and the fifth leading cause of cancer-related deaths in men. Prostate-specific membrane antigen (PSMA) as a target has gained increasing attention. This resea...
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Article
Periostin–TGF-β feedforward loop contributes to tumour-stroma crosstalk in liver metastatic outgrowth of colorectal cancer
This study aimed to investigate the underlying mechanisms of matricellular protein periostin (POSTN) on tumour-stroma crosstalk in the liver metastatic microenvironment of colorectal cancer (CRC).
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Article
Highly efficient determination of metal ion in cosmetic samples by reversed-phase liquid–liquid microextraction based on green hydrophobic deep eutectic solvent
In this paper, a green hydrophobic deep eutectic solvent (HDES) composed of menthol and hexanoic acid was employed to dissolve cosmetics containing Cd2+ and Cd2+ was extracted using an EDTA-2Na saturated solution...
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Chapter and Conference Paper
Mining Label Distribution Drift in Unsupervised Domain Adaptation
Unsupervised domain adaptation targets to transfer task-related knowledge from labeled source domain to unlabeled target domain. Although tremendous efforts have been made to minimize domain divergence, most e...
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Article
Matching Relationships for Mechanical Parameters of Asphalt Pavement Materials Considering Difference in Tension and Compression
In view of the non-uniqueness of modulus selection and the mismatch among the values of various mechanical parameters of the same material in the current asphalt pavement design, typical pavement materials, as...
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Article
Open AccessComprehensive analysis of immune cell landscapes revealed that immune cell ratio eosinophil/B.cell.memory is predictive of survival in sepsis
Immune dysregulation is a feature of sepsis. However, a comprehensive analysis of the immune landscapes in septic patients has not been conducted.
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Article
Comparison of transfusion rates between robotic- and video-assisted lobectomy: a propensity score matching analysis
The objective is to compare the perioperative blood transfusion rate and postoperative complications between robot-assisted surgery and thoracoscopic surgery in lung cancer patients. This is a single-center re...
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Article
Effects of thinning and understorey removal on soil extracellular enzyme activity vary over time during forest recovery after treatment
Soil extracellular enzyme activities (EEAs) and extracellular enzymatic stoichiometry (EES) play an important role in soil nutrient cycling processes. However, the response of EEAs and EES to forest management...
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Article
Open AccessMpADC, an l-aspartate-α-decarboxylase, from Myzus persicae, that enables production of β-alanine with high yield by whole-cell enzymatic catalysis
β-Alanine is a precursor of many important pharmaceutical products and food additives, its market demand is continuously increasing nowadays. Whole-cell catalysis relying on the recombinant expression of key β...
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Article
Open AccessConditional knockout of PDK1 in osteoclasts suppressed osteoclastogenesis and ameliorated prostate cancer-induced osteolysis in murine model
The development and maintenance of normal bone tissue is maintained by balanced communication between osteoblasts and osteoclasts. The invasion of cancer cells disrupts this balance, leading to osteolysis. As ...
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Article
Natural restoration of degraded karst vegetation shifts soil microbial phosphorus acquisition strategies
Soil phosphorus (P) cycling in karst regions is mainly regulated by microbial activities. Natural restoration has been widely adopted in the degraded karst regions of southwest China. However, the response of ...
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Article
Ceramic art image design based on neural network and particle image algorithm
In recent years, scientists have developed a new type of algorithm called convolutional neural network algorithm in the field of neural networks. This algorithm not only has a powerful image recognition functi...
