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  1. Article

    Open Access

    Develo** a CRISPR/FrCas9 system for core promoter editing in rice

    Small mutations in the core promoter region of a gene may result in substantial changes in expression strengths. However, targeting TA-rich sequences of core promoters may pose a challenge for Cas9 variants su...

    Hui Wang, Jian Ding, **gyan Zhu, **aoshuang Liu, Rongfang Xu, Ruiying Qin in aBIOTECH (2024)

  2. Article

    Open Access

    Conditional knockdown of OsMLH1 to improve plant prime editing systems without disturbing fertility in rice

    High-efficiency prime editing (PE) is desirable for precise genome manipulation. The activity of mammalian PE systems can be largely improved by inhibiting DNA mismatch repair by coexpressing a dominant-negati...

    **aoshuang Liu, Dongfang Gu, Yiru Zhang, Yingli Jiang, Zhi **ao in Genome Biology (2024)

  3. No Access

    Article

    Multigram‑scale synthesis of BTK inhibitor BIIB068

    This paper describes the development of a relatively feasible, economic, and safe method for the multigram-scale synthesis of BIIB068, an efficient reversible BTK inhibitor. The new process is highlighted by an e...

    Donghao Jia, Mingfang Gu, **nyue Yu, Kunyang Yuan, Sixuan Wang in Chemical Papers (2023)

  4. No Access

    Article

    Exploring the impact of natural resources and energy transition on CO2 intensity in China

    As reported at the 26th UN Climate Change Conference (COP26), worsening climate situation has led to frequent extreme weather events around the world. The main cause of climate change is carbon emissions from ...

    Fangfang Gu, **aohong Liu in Environmental Science and Pollution Research (2023)

  5. No Access

    Article

    Fine map** and candidate gene analysis of gummy stem blight resistance in cucumber stem

    Two candidate genes (Csa6G046210 and Csa6G046240) were identified by fine-map** gsb-s6.2 for gummy stem blight resistance in cucumber stem.

    Jianan Han, Shaoyun Dong, Yanxia Shi, Han Miao in Theoretical and Applied Genetics (2022)

  6. No Access

    Article

    The qLTG1.1 candidate gene CsGAI regulates low temperature seed germination in cucumber

    The CsGAI gene, identified by map-based, was involved in regulating seed germination in low temperature via the GA and ABA signaling pathways.

    Caixia Li, Shaoyun Dong, Diane M. Beckles, Han Miao in Theoretical and Applied Genetics (2022)

  7. No Access

    Chapter and Conference Paper

    Research on Measurement Method of Adaptive Driving Beam

    In recent years, adaptive driving beam has become a development trend of automobile headlight, which does not dazzle the drivers of other vehicles, and at the same time guarantees the effect of driving beam to...

    Guanqun Ye, Peixiang Wang, Bing Gong in Proceedings of China SAE Congress 2020: Se… (2022)

  8. No Access

    Article

    Experimental Study on Condensation Heat Transfer Characteristics inside an Inclined Wave-Finned Flat Tube of Direct Air-Cooling System

    In this paper, the condensation heat transfer characteristics of parallel flow and counter flow inside an inclined wave-finned flat tube is investigated experimentally. The condensation heat transfer coefficie...

    Haitao Wang, Tao Tao, Xuesong Mei, Haijun Wang, Hongfang Gu in Journal of Thermal Science (2021)

  9. Article

    Open Access

    QTL map** and genome-wide association study reveal two novel loci associated with green flesh color in cucumber

    Green flesh color, resulting from the accumulation of chlorophyll, is one of the most important commercial traits for the fruits. The genetic network regulating green flesh formation has been studied in tomato...

    Kailiang Bo, Shuang Wei, Wei** Wang, Han Miao, Shaoyun Dong in BMC Plant Biology (2019)

  10. No Access

    Article

    Phylogenetic and Expression Analysis of Mn-CDF Transporters in Pear (Pyrus bretschneideri Rehd.)

    Metal tolerance proteins (MTPs) play important roles in heavy metal homeostasis and tolerance in plants. As a part of the MTP family, manganese-cation diffusion facilitator (Mn-CDF) subfamily members transport...

    Lei Hou, Dongfang Gu, Yun Li, Jiyu Li, **gjun Li in Plant Molecular Biology Reporter (2019)

  11. No Access

    Article

    Novel loci fsd6.1 and Csgl3 regulate ultra-high fruit spine density in cucumber

    Quantitative Trait Loci (QTL) analysis of multiple populations in multiple environments revealed that the fsd6.2 locus, which includes the candidate gene Csgl3, controls high fruit spine density in natural cucumb...

    Kailiang Bo, Han Miao, Min Wang, in Theoretical and Applied Genetics (2019)

  12. No Access

    Article

    Genetic analysis and identification of a candidate gene associated with in vitro regeneration ability of cucumber

    Candidate genes associated with in vitro regeneration were identified in cucumber.

    Ye Wang, Qian Zhou, Guangtao Zhu, Shenhao Wang in Theoretical and Applied Genetics (2018)

  13. No Access

    Article

    Combined fine map**, genetic diversity, and transcriptome profiling reveals that the auxin transporter gene ns plays an important role in cucumber fruit spine development

    Map-based cloning was used to identify the ns gene, which was involved in the formation of cucumber numerous fruit spines together with other genes under regulation by plant hormone signal transduction.

    Qing **e, Panna Liu, Lixue Shi, Han Miao, Kailiang Bo in Theoretical and Applied Genetics (2018)

  14. No Access

    Article

    Inheritance and QTL map** of resistance to gummy stem blight in cucumber stem

    Gummy stem blight (GSB), a common disease of all major cucurbits, is caused by the fungus Didymella bryoniae. It results in serious losses in fruit production, which in cucumber can be up to 80% or more. Because ...

    Sheng** Zhang, Shulin Liu, Han Miao, Yanxia Shi, Min Wang, Ye Wang in Molecular Breeding (2017)

  15. No Access

    Article

    Genetic analysis and fine map** of Watermelon mosaic virus resistance gene in cucumber

    Watermelon mosaic virus (WMV) is an important disease of cucumber (Cucumis sativus L.) that is difficult to control in the field. Some resistant lines are available, and understanding the...

    Guili Tian, Han Miao, Yuhong Yang, Jian Zhou, Hongwei Lu, Ye Wang in Molecular Breeding (2016)

  16. No Access

    Article

    Genetic analysis and gene map** of papaya ring spot virus resistance in cucumber

    The papaya ring spot virus (PRSV) causes significant fruit yield loss in cucurbit crops. Understanding of the inheritance and molecular map** of PRSV resistance will facilitate development of resistant varietie...

    Guili Tian, Yuhong Yang, Sheng** Zhang, Han Miao, Hongwei Lu in Molecular Breeding (2015)

  17. No Access

    Article

    A genomic variation map provides insights into the genetic basis of cucumber domestication and diversity

    Sanwen Huang and colleagues report a genomic variation map of cucumber. They report the resequencing of 115 cucumber accessions and de novo assembly of the wild cucumber genome.

    Jianjian Qi, **n Liu, Di Shen, Han Miao, Bingyan **e, **xiang Li in Nature Genetics (2013)

  18. Article

    Open Access

    A 1,681-locus consensus genetic map of cultivated cucumber including 67 NB-LRR resistance gene homolog and ten gene loci

    Cucumber is an important vegetable crop that is susceptible to many pathogens, but no disease resistance (R) genes have been cloned. The availability of whole genome sequences provides an excellent opportunity...

    Luming Yang, Dawei Li, Yuhong Li, **ngfang Gu, Sanwen Huang in BMC Plant Biology (2013)

  19. No Access

    Article

    A linkage map of cultivated cucumber (Cucumis sativus L.) with 248 microsatellite marker loci and seven genes for horticulturally important traits

    A genetic map was developed with microsatellite (simple sequence repeat, SSR) markers and 148 recombinant inbred lines (RILs) derived from a cross between two cultivated cucumber (Cucumis sativus L.) inbred lines...

    Han Miao, Sheng** Zhang, **aowu Wang, Zhonghua Zhang, Man Li, Shengqi Mu in Euphytica (2011)

  20. Article

    Open Access

    Genome-wide analysis of WRKY gene family in Cucumis sativus

    WRKY proteins are a large family of transcriptional regulators in higher plant. They are involved in many biological processes, such as plant development, metabolism, and responses to biotic and abiotic stress...

    Jian Ling, Weijie Jiang, Ying Zhang, Hongjun Yu, Zhenchuan Mao, **ngfang Gu in BMC Genomics (2011)

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