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Article
Open AccessAnalysis of the synergistic benefits of typical technologies for pollution reduction and carbon reduction in the iron and steel industry in the Bei**g–Tian**–Hebei region
With its high energy consumption and pollutant emissions, the iron and steel industry is a significant source of air pollution and carbon emissions in the Bei**g–Tian**–Hebei (BTH) region. To improve air qua...
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Article
Open AccessReciprocal regulation of forkhead box C1 and L1 cell adhesion molecule contributes to triple-negative breast cancer progression
The potential of targeting forkhead box C1 (FOXC1) as a therapeutic approach for triple-negative breast cancer (TNBC) is promising. However, a comprehensive understanding of FOXC1 regulation, particularly upst...
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Article
D \(^2\) WA: “dynamic” DWA for motion planning of mobile robots in dynamic environments
The paper presents a novel method called D \(^2\) 2 ...
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Article
CO2 emission accounting and emission reduction analysis of the steel production process based on the material-energy-carbon correlation effect
This paper develops a process-level carbon emission calculation model for iron and steel enterprises through the carbon emission mechanism of the whole production process. The relationship between material, en...
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Article
Potential application of a novel building-integrated solar facade water heating system in a subtropical climate: A case study for school canteen
The design and potential application analysis of the novel solar-absorbing integrated facade module and its corresponding building-integrated solar facade water heating system are presented in this study. Comp...
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Article
Orelabrutinib and venetoclax synergistically induce cell death in double-hit lymphoma by interfering with the crosstalk between the PI3K/AKT and p38/MAPK signaling
Double-hit lymphoma (DHL) is a rare and aggressive mature B-cell malignancy with concurrent MYC and BCL2 rearrangements. When DHL becomes relapsed or refractory, it becomes resistant to the majority of therape...
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Article
Open AccessAbnormal expression of fission and fusion genes and the morphology of mitochondria in eutopic and ectopic endometrium
Mitochondria play a pivotal role in physiological and metabolic function of the cell. Mitochondrial dynamics orchestrate mitochondrial function and morphology, involving fission and fusion as well as ultrastru...
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Article
Open AccessRitanserin suppresses acute myeloid leukemia by inhibiting DGKα to downregulate phospholipase D and the Jak-Stat/MAPK pathway
Refractory or relapsed (R/R) AML is the most challenging form of AML to treat. Due to frequent genetic mutations, therapy alternatives are limited. Here, we identified the role of ritanserin and its target DGK...
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Article
Open AccessLymphocyte integrins mediate entry and dysregulation of T cells by SARS-CoV-2
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Chapter and Conference Paper
Workflow for Generating Personalised Anatomical Models of the Skeleton and the Skin Surface of the Upper Torso
Breast cancer is the leading cause of cancer-related death in women worldwide. Diagnostic imaging such as 3D magnetic resonance imaging (MRI) is acquired with patients positioned in the prone orientation with ...
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Article
Open AccessManipulations of phenylnorbornyl palladium species for multicomponent construction of a bridged polycyclic privileged scaffold
Hexahydromethanocarbazole is a privileged scaffold in the discovery of new drugs and photoactive organic materials due to its good balance between structural complexity and minimized entropy penalty upon recep...
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Article
Open AccessARSD, a novel ERα downstream target gene, inhibits proliferation and migration of breast cancer cells via activating Hippo/YAP pathway
Advanced breast cancer (BC), especially basal like triple-negative BC (TNBC), is a highly malignant tumor without viable treatment option, highlighting the urgent need to seek novel therapeutic targets. Arylsu...
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Article
Open AccessHistone deacetylase 2 knockout suppresses immune escape of triple-negative breast cancer cells via downregulating PD-L1 expression
The PD-L1 overexpression is an important event of immune escape and metastasis in triple-negative breast cancer (TNBC), but the molecular mechanism remains to be determined. Interferon gamma (IFNγ) represents ...
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Article
Dynamic thermal buckling and postbuckling of clamped–clamped imperfect functionally graded annular plates
Dynamic thermal buckling and postbuckling of imperfect functionally graded material (FGM) annular plates are investigated based on the nonlinear plate theory. The transient temperature fields of the FGM annula...
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Article
Fabrication and characterization of BaCe0.8Y0.2O2.9-Ce0.85Sm0.15O1.925 composite electrolytes for IT-SOFCs
The BaCe0.8Y0.2O2.9-Ce0.85Sm0.15O1.925 composite electrolytes were prepared with BaCe0.8Y0.2O2.9 (BCY) and Ce0.85Sm0.15O1.925 (SDC). The SDC and BCY powders were mixed in the weight ratio of 95:5, 85:15, and 75:2...
