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Chapter
A Temporal-Spatial Correlation Theory and Experiment for Visualization of Ultrasonic Wavefront
Visualization of ultrasonic field is special interest for non-destructive evaluation, acousto-optic information processing, non-linear acoustics, etc. Early works are showing the intensity distribution of low ...
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Article
Reovirus, isolated from SARS patients
Bei**g has been severely affected by SARS, and SARS-associated coronavirus has been confirmed as its cause. However, clinical and experimental evidence implicates the possibility of co-infection. In this repo...
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Article
Ile118Val genetic polymorphism of CYP3A4 and its effects on lipid-lowering efficacy of simvastatin in Chinese hyperlipidemic patients
To determine the frequencies of CYP3A4 alleles (CYP3A4*4,*5 and *6) in Chinese hyperlipidemic patients and to observe the impact of CYP3A4*4 (Ile118Val) genetic polymorphism on the lipid-lowering effects of simva...
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Article
Basic fibroblast growth factor alleviates brain injury following global ischemia reperfusion in rabbits
The aim of this study was to explore the protective effect of basic fibroblast growth factor (bFGF) on brain injury following global ischemia reperfusion and its mechanisms. Brain injury following global ische...
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Chapter
Case History — Use of ADME Studies for Optimization of Drug Candidates
Efficacy and safety are the two key elements in the drug discovery and development processes. The primary goal for pharmaceutical research companies is to identify and manufacture therapeutic agents that are s...
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Article
Regulations and roles of the interleukin-1 receptor associated kinases (IRAKs) in innate and adaptive immunity
The interleukin-1 receptor associated kinases (IRAKs) are critically involved in the IL-1R/Toll-like receptor (TLR)-mediated signal transduction processes and therefore regulate, cellular innate immune respons...
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Article
Identification and functional characterization of a leucine-rich repeat receptor-like kinase gene that is involved in regulation of soybean leaf senescence
We report here the cloning and characterization of a soybean receptor-like kinase (RLK) gene, designated GmSARK (Glycine max senescence-associated receptor-like kinase), which is involved in regulating leaf senes...
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Article
Open AccessRecent advances in basic neurosciences and brain disease: from synapses to behavior
Understanding basic neuronal mechanisms hold the hope for future treatment of brain disease. The 1st international conference on synapse, memory, drug addiction and pain was held in beautiful downtown Toronto,...
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Article
Open AccessAchieving a high coverage – the challenge of controlling HIV spread in heroin users
In China, the national plan to open 1000 methadone clinics over a five-year period provides a unique opportunity to assess the impacts of harm reduction in a country with concentrated HIV epidemic amongst hero...
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Article
Numerical Simulation of Austenite Recrystallization in CSP Hot Rolled C-Mn Steel Strip
An integrated mathematical model is developed to predict the microstructure evolution of C-Mn steel during multipass hot rolling on the CSP production line, and the thermal evolution, the temperature distribut...
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Article
Experience and thinking on study of pneumonectomy by acupuncture anesthesia
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Article
**hua population as an exception of Han Chinese’s coherent genetic structure
The Han Chinese is the largest single ethnic group in the world, consisting of ten Chinese branches. With the exception of the **hua branch, the genetic structure of this group has been studied extensively, ...
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Article
GPS-constrained inversion of present-day slip rates along major faults of the Sichuan-Yunnan region, China
A linked-fault-element model is employed to invert for contemporary slip rates along major active faults in the Sichuan-Yunnan region (96°–108°E, 21°–35°N) using the least squares method. The model is based on...
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Article
Molecular Identification of cDNA, Immunolocalization, and Expression of a Putative Odorant-Binding Protein from an Asian Honey Bee, Apis cerana cerana
An odorant-binding protein cDNA (Acer-ASP2) was cloned and characterized from antennae of adult workers of an Asian honey bee, Apis cerana cerana F. (Hymenoptera: Apidae). The full-length open reading frame of Ac...
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Article
Waterbird Population Changes in the Wetlands at Chongming Dongtan in the Yangtze River Estuary, China
We studied the changes in wetland habitats and waterbird communities between the 1980s and the 2000s at Chongming Dongtan, a Ramsar site in the Yangtze River estuary, an ecologically important region. This reg...
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Article
Open AccessStudy of RNA interference inhibiting rat ovarian androgen biosynthesis by depressing 17alpha-hydroxylase/17, 20-lyase activity in vivo
17alpha-hydroxylase/17, 20-lyase encoded by CYP17 is the key enzyme in androgen biosynthesis pathway. Previous studies demonstrated the accentuation of the enzyme in patients with polycystic ovary syndrome (PC...
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Article
Effect of select medium supplements on in vitro development of Cryptosporidium andersoni in HCT-8 cells
We evaluated the effect of fetal calf serum (FCS), glucose, ascorbic acid, calcium pantothenate, folic acid, and insulin on the growth of Cryptosporidium andersoni in human colon tumor (HCT-8) cells. After being ...
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Article
The actuarial survival analysis of the surgical and non-surgical therapy regimen for chronic thromboembolic pulmonary hypertension
Aim To characterize the in-hospital mortality and the actuarial survival of surgical and non-surgical therapy regimen in the treatment of chronic thromboembolic pulmonary hypertension (CT...
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Article
D-dimer as a predictor of progressive hemorrhagic injury in patients with traumatic brain injury: analysis of 194 cases
This study sought to describe and evaluate any relationship between D-dimer values and progressive hemorrhagic injury (PHI) after traumatic brain injury (TBI). In patients with TBI, plasma D-dimer was measured...
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Article
Therapeutic potential and challenges of targeting sirtuins in neurodegenerative diseases
Aging is the predominant risk factor for major neurodegenerative diseases. The underlying mechanisms are largely unknown. Members of the sirtuin family of protein deacetylases support and promote longevity in ...
