58 Result(s)

Article

Baicalin inhibits PDGF-BB-stimulated vascular smooth muscle cell proliferation through suppressing PDGFRβ-ERK signaling and increase in p27 accumulation and prevents injury-induced neointimal hyperplasia

The increased proliferation and migration of vascular smooth muscle cells (VSMCs) are key events in the development of atherosclerotic lesions. Baicalin, an herb-derived flavonoid compound, has been previously...

Li-Hua Dong, **-Kun Wen, Sui-Bing Miao, Zhenhua Jia, Hai-Juan Hu… in Cell Research (2010)

Article

A switch from hBrm to Brg1 at IFNγ-activated sequences mediates the activation of human genes

The SWI/SNF chromatin-remodeling complexes utilize energy from ATP hydrolysis to reposition nucleosomes and regulate the expression of human genes. Here, we studied the roles of human Brahma (hBrm) and Brahma-...

Yi Zhang, Mo-bin Cheng, Yan-jun Zhang, **n Zhong, Hui Dai, Li Yan… in Cell Research (2010)

Article

Erratum: Baicalin inhibits PDGF-BB-stimulated vascular smooth muscle cell proliferation through suppressing PDGFRβ-ERK signaling and increase in p27 accumulation and prevents injury-induced neointimal hyperplasia

Correction to: Cell Research (2011) 20:1252–1262. doi:10.1038/cr.2010.111; published online 27 July 2010 The authors would like to clarify a deficiency in our paper recently published in Cell Research (CR) (20...

Li-Hua Dong, **-Kun Wen, Sui-Bing Miao, Zhenhua Jia, Hai-Juan Hu… in Cell Research (2011)

Article

Generation of dopaminergic neurons directly from mouse fibroblasts and fibroblast-derived neural progenitors

Chao Sheng, Qinyuan Zheng, Jianyu Wu, Zhen Xu, Lisi Sang, Libin Wang… in Cell Research (2012)

Article

Crystal structures of two phytohormone signal-transducing α/β hydrolases: karrikin-signaling KAI2 and strigolactone-signaling DWARF14

Li-Hua Zhao, X Edward Zhou, Zhong-Shan Wu, Wei Yi, Yong Xu, Suling Li… in Cell Research (2013)

Article

Pachytene piRNAs instruct massive mRNA elimination during late spermiogenesis

Spermatogenesis in mammals is characterized by two waves of piRNA expression: one corresponds to classic piRNAs responsible for silencing retrotransponsons and the second wave is predominantly derived from non...

Lan-Tao Gou, Peng Dai, Jian-Hua Yang, Yuanchao Xue, Yun-** Hu, Yu Zhou… in Cell Research (2014)

Article

Pachytene piRNAs instruct massive mRNA elimination during late spermiogenesis

Lan-Tao Gou, Peng Dai, Jian-Hua Yang, Yuanchao Xue, Yun-** Hu, Yu Zhou… in Cell Research (2015)

Article

saRNA-guided Ago2 targets the RITA complex to promoters to stimulate transcription

Small activating RNAs (saRNAs) targeting specific promoter regions are able to stimulate gene expression at the transcriptional level, a phenomenon known as RNA activation (RNAa). It is known that RNAa depends...

Victoria Portnoy, Szu Hua Sharon Lin, Kathy H Li, Alma Burlingame… in Cell Research (2016)

Article

Activation of transient receptor potential vanilloid 4 involves in hypoxia/reoxygenation injury in cardiomyocytes

Transient receptor potential vanilloid 4 (TRPV4) is highly expressed in heart and vessels and can be activated during myocardial ischemia/reperfusion (I/R). Recently, we found that treatment with a selective T...

Qiong-Feng Wu, Cheng Qian, Ning Zhao, Qian Dong, **g Li… in Cell Death & Disease (2017)

Article

Promoting tumorigenesis in nasopharyngeal carcinoma, NEDD8 serves as a potential theranostic target

Nasopharyngeal carcinoma (NPC), is one of the most common human malignancies in south China, it has the highest recurrence rate and treatment resistance. The underlying molecular mechanisms of NPC relapse and ...

** **e, Jun-** Yang, Yun Cao, Li-**a Peng, Li-Sheng Zheng… in Cell Death & Disease (2017)

Article

Long noncoding RNA XIST expedites metastasis and modulates epithelial–mesenchymal transition in colorectal cancer

Tumor progression and metastasis is the main cause of death in colorectal cancer (CRC). Long noncoding RNAs (lncRNAs) are critical regulators in various diseases including human cancer. In this study, we found...

Dong-liang Chen, Le-zong Chen, Yun-xin Lu, Dong-sheng Zhang… in Cell Death & Disease (2017)

Article

BCL6 attenuates renal inflammation via negative regulation of NLRP3 transcription

Renal inflammation contributes to the pathogeneses of hypertension. This study was designed to determine whether B-cell lymphoma 6 (BCL6) attenuates renal NLRP3 inflammasome activation and inflammation and its...

Dan Chen, **ao-Qing **ong, Ying-Hao Zang, Ying Tong, Bing Zhou… in Cell Death & Disease (2017)

Article

2-aminopurine suppresses the TGF-β1-induced epithelial–mesenchymal transition and attenuates bleomycin-induced pulmonary fibrosis

The epithelial–mesenchymal transition (EMT) is a multifunctional cell process involved in the pathogenesis of numerous conditions, including fibrosis and cancer. Idiopathic pulmonary fibrosis (IPF) is a progre...

Dong Weng, Jian-xia Chen, Hao-hao Li, Feng Liu, Li-dan Zhou… in Cell Death Discovery (2018)

Article

Molecular characterization and integrative genomic analysis of a panel of newly established penile cancer cell lines

Cell line models are essential tools to study the molecular mechanisms underlying tumor initiation and progression. There are limited treatment options for penile squamous cell carcinoma (PSCC), accounting for...

Qiang-hua Zhou, Chuang-zhong Deng, Zai-shang Li, Jie-** Chen… in Cell Death & Disease (2018)