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Aberrant Enhanced NLRP3 Inflammasomes and Cell Pyroptosis in the Brains of Prion-Infected Rodent Models Are Largely Associated with the Proliferative Astrocytes

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  1. Article

    Open Access

    Nicotinamide riboside restores nicotinamide adenine dinucleotide levels and alleviates brain injury by inhibiting oxidative stress and neuroinflammation in a mouse model of intracerebral hemorrhage

    Hemorrhagic stroke is a global health problem owing to its high morbidity and mortality rates. Nicotinamide riboside is an important precursor of nicotinamide adenine dinucleotide characterized by a high bioav...

    **g She, Hua Zhang, Hui Xu, Yan-Yan Li, Jun-Chao Wu, Rong Han in Molecular Neurobiology (2024)

  2. Article

    Open Access

    Systemic inflammation and insulin resistance-related indicator predicts poor outcome in patients with cancer cachexia

    The C-reactive protein (CRP)-triglyceride-glucose (TyG) index (CTI), which is a measure representing the level of inflammation and insulin resistance (IR), is related to poor cancer prognosis; however, the CTI...

    Guo-Tian Ruan, Li Deng, Hai-Lun **e, **-Yu Shi, **ao-Yue Liu in Cancer & Metabolism (2024)

  3. Article

    Open Access

    Interplay between lncRNA RP11-367G18.1 variant 2 and YY1 plays a vital role in hypoxia-mediated gene expression and tumorigenesis

    The hypoxia-responsive long non-coding RNA, RP11-367G18.1, has recently been reported to induce histone 4 lysine 16 acetylation (H4K16Ac) through its variant 2; however, the underlying molecular mechanism remains...

    Pei-Hua Peng, Ji-Lin Chen, Heng-Hsiung Wu, Wen-Hao Yang in Cancer Cell International (2023)

  4. Article

    Open Access

    A novel quinoline derivative, DFIQ, sensitizes NSCLC cells to ferroptosis by promoting oxidative stress accompanied by autophagic dysfunction and mitochondrial damage

    The development of nonapoptotic programmed cell death inducers as anticancer agents has emerged as a cancer therapy field. Ferroptosis, ferrous ion-driven programmed cell death that is induced by redox imbalan...

    Yung-Ding Bow, Ching-Chung Ko, Wen-Tsan Chang, Sih-Yan Chou in Cancer Cell International (2023)

  5. Article

    Open Access

    Apatinib plus vinorelbine versus vinorelbine for metastatic triple-negative breast cancer who failed first/second-line treatment: the NAN trial

    While therapies such as chemotherapy combined with immunotherapy, sacituzumab govitecan, and PARP inhibitors are available for metastatic TNBC, on disease progression after these therapies, the mainstay of the...

    Dou-Dou Li, Zhong-hua Tao, Bi-Yun Wang, Lei-** Wang, Jun Cao in npj Breast Cancer (2022)

  6. Article

    Open Access

    Systematic analysis of gene expression profiles reveals prognostic stratification and underlying mechanisms for muscle-invasive bladder cancer

    Muscle-invasive bladder cancer (MIBC) is originated in the muscle wall of the bladder, and is the ninth most common malignancy worldwide. However, there are no reliable, accurate and robust gene signatures for...

    **-Bao Zhang, Zi-Li Huang, Yong-Hua Xu, ** Huang in Cancer Cell International (2019)

  7. Article

    Open Access

    The predictive and prognostic role of a novel ADS score in esophageal squamous cell carcinoma patients undergoing esophagectomy

    Chronic inflammation is deemed to play a significant effect on initiation and progression of esophageal squamous cell carcinoma (ESCC). In current study, we investigated the prognostic and predictive role of a...

    Qiu-Fang Gao, Jia-Cong Qiu, **ao-Hong Huang, Yan-Mei Xu in Cancer Cell International (2018)

  8. Article

    Open Access

    Cumulative receiver operating characteristics for analyzing interaction between tissue visfatin and clinicopathologic factors in breast cancer progression

    Visfatin has been reported to be associated with breast cancer progression, but the interaction between the visfatin and clinicopathologic factors in breast cancer progression status requires further investiga...

    Sin-Hua Moi, Yi-Chen Lee, Li-Yeh Chuang, Shyng-Shiou F. Yuan in Cancer Cell International (2018)

  9. Article

    Erratum to: Endogenous TGFβ1 Plays a Crucial Role in Functional Recovery After Traumatic Brain Injury Associated with Smad3 Signal in Rats

    Xu-Yang Wang, Ying-Chun Ba, Liu-Lin **ong, **ao-li Li, Yu Zou in Neurochemical Research (2016)

  10. Article

    Open Access

    Correlation between HER-2/neu(erbB-2) expression level and therapeutic effect of combination treatment with HERCEPTIN and chemotherapeutic agents in gastric cancer cell lines

    Although advanced gastric cancer has many limitations and response rate is marginal in chemotherapy. Overexpression of human epidermal growth factor receptor 2(HER-2/neu) gene and its protein are associated with ...

    Hai Cui, Ying Cheng, Su-Zhou Piao, Yun-Jie Xu, Hong-Hua Sun in Cancer Cell International (2014)

  11. Article

    Erratum to: Fas and FasL Expression in the Spinal Cord Following Cord Hemisection in the Monkey

    Liu Jia, Zou Yu, Li Hui, Guan Yu-Guang, Zhou **n-Fu, You Chao in Neurochemical Research (2011)

  12. Article

    Erratum to: Recombinant DNA Vaccine Against Inhibition of Neurite Outgrowth Promotes Functional Recovery Associated with Endogeous NGF Expression in Spinal Cord Hemisected Adult Rats

    Yi Zhang, Chun-Guang Hao, Li-Qun Hu, Jian Dong, Peng Wei, Dan Xu in Neurochemical Research (2010)

  13. Article

    Changes in Glial Cell Line-derived Neurotrophic Factor Expression in the Rostral and Caudal Stumps of the Transected Adult Rat Spinal Cord

    Hao-Li Zhou, Hui-Juan Yang, Yong-Mei Li, Ying Wang, Ling Yan in Neurochemical Research (2008)

  14. Article

    Transplantation of NGF-Gene-Modified Bone Marrow Stromal Cells into a Rat Model of Alzheimer’ Disease

    Li-Yan Li, **-Tao Li, Qing-Ying Wu, ** Li in Journal of Molecular Neuroscience (2008)

  15. Article

    Open Access

    Changes in Glial Cell Line-derived Neurotrophic Factor Expression in the Rostral and Caudal Stumps of the Transected Adult Rat Spinal Cord

    Limited information is available regarding the role of endogenous Glial cell line-derived neurotrophic factor (GDNF) in the spinal cord following transection injury. The present study investigated the possible...

    Hao-Li Zhou, Hui-Juan Yang, Yong-Mei Li, Ying Wang, Ling Yan in Neurochemical Research (2008)