Skip to main content

3 Result(s)

within Vaccine Remove this filter **ng-Zhao Ye Remove this filter

and

  1. No Access

    Article

    Cytosolic DNA initiates a vicious circle of aging-related endothelial inflammation and mitochondrial dysfunction via STING: the inhibitory effect of Cilostazol

    Endothelial senescence, aging-related inflammation, and mitochondrial dysfunction are prominent features of vascular aging and contribute to the development of aging-associated vascular disease. Accumulating e...

    Zhi-hua Zheng, Jiao-jiao Wang, Jiu-guo Lin, Wei-le Ye… in Acta Pharmacologica Sinica (2024)

  2. No Access

    Article

    Targeting HMGB1 for the treatment of sepsis and sepsis-induced organ injury

    High mobility group box 1 (HMGB1) is a ubiquitous nuclear protein that is present in almost all cells and regulates the activity of innate immune responses in both intracellular and extracellular settings. Cur...

    Chao Deng, Lin Zhao, Zhi Yang, Jia-jia Shang, Chang-yu Wang… in Acta Pharmacologica Sinica (2022)

  3. No Access

    Article

    Establishment of an in vitro safety assessment model for lipid-lowering drugs using same-origin human pluripotent stem cell-derived cardiomyocytes and endothelial cells

    Cardiovascular safety assessment is vital for drug development, yet human cardiovascular cell models are lacking. In vitro mass-generated human pluripotent stem cell (hPSC)-derived cardiovascular cells are a s...

    Xuan Ni, Zhuang-zhuang Yang, Ling-qun Ye, **ng-long Han… in Acta Pharmacologica Sinica (2022)