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Article
Open AccessAttitudes toward an HPV vaccine for condyloma acuminata and willingness to undergo vaccination among STD clinic attendees in China: Focus on STI prevention with HPV vaccine
Condyloma acuminata (CA) is a common, and recurrent sexually transmitted disease (STD) that greatly contributes to direct health care costs and has a substantial psychosocial impact. Human papillomavirus (HPV)...
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Article
AgRP neurons control structure and function of the medial prefrontal cortex
Hypothalamic agouti-related peptide and neuropeptide Y-expressing (AgRP) neurons have a critical role in both feeding and non-feeding behaviors of newborn, adolescent, and adult mice, suggesting their broad mo...
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Article
Open AccessActivation of neural lineage networks and ARHGEF2 in enzalutamide-resistant and neuroendocrine prostate cancer and association with patient outcomes
Treatment-emergent neuroendocrine prostate cancer (NEPC) after androgen receptor (AR) targeted therapies is an aggressive variant of prostate cancer with an unfavorable prognosis. The underlying mechanisms for...
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Article
Open AccessDetection of an anti-angina therapeutic module in the effective population treated by a multi-target drug Danhong injection: a randomized trial
It’s a challenge for detecting the therapeutic targets of a polypharmacological drug from variations in the responsed networks in the differentiated populations with complex diseases, as stable coronary heart ...
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Article
Open AccessTreatment outcomes of patients with multidrug and extensively drug-resistant tuberculosis in Zhejiang, China
The aim of this study was to assess the treatment outcomes of multidrug and extensively drug-resistant tuberculosis (M/XDR-TB) in Zhejiang, China and to evaluate possible risk factors associated with poor outc...
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Article
Whether Fire-needle Therapy Benefits Plaque Psoriasis: A Multicenter, Randomized, and Controlled Trial
To observe the clinical effectiveness and safety of fire-needle therapy, an external approach of Chinese medicine in treating plaque psoriasis.
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Article
Application of the Guiding Template Designed by Three-dimensional Printing Data for the Insertion of Sacroiliac Screws: a New Clinical Technique
This study is aimed to explore the clinical application of the guiding template designed by three-dimensional printing data for the insertion of sacroiliac screws. A retrospective study of 7 cases (from July 2...
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Article
Erratum to: Promotion of chondrogenesis of marrow stromal stem cells by TGF-β3 fusion protein In Vivo
The original version of this article unfortunately contained a mistake. The presentation of the title was incorrect. The corrected title is given below.
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Article
Open AccessA multicenter, randomized, double-blind, placebo-controlled trial evaluating the efficacy and safety of Tong Luo Hua Shi capsule, a modernized Tibetan medicine, in patients with rheumatoid arthritis
Tong Luo Hua Shi (TLHS) is a new formulation of the traditional Tibetan medicine Wu-wei-gan-lu that has been used for the treatment of rheumatoid arthritis (RA) for hundreds of years in China. This study aimed...
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Article
Novel application of vacuum sealing drainage with continuous irrigation of potassium permanganate for managing infective wounds of gas gangrene
Traumatic gas gangrene is a fatal infection mainly caused by Clostridium perfringens. It is a challenge to manage gas gangrene in open wounds and control infection after debridement or amputation. The aim of the ...
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Article
Open AccessRisk factors for post-ERCP pancreatitis: a systematic review of clinical trials with a large sample size in the past 10 years
Post- endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis (PEP) is the most common and most severe complication associated with diagnostic and therapeutic ERCP. A multivariate analysis of risk f...
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Article
Promotion of chondrogenesis of marrow stromal stem cells by TGF-β3 fusion protein in vitro
The purpose of this study was to investigate the repair of the osteoarthritis(OA)-induced cartilage injury by transfecting the new TGF-β3 fusion protein (LAP-MMP-mTGF-β3) with targeted therapy function into th...
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Article
Construction of self-assembled cartilage tissue from bone marrow mesenchymal stem cells induced by hypoxia combined with GDF-5
It is widely known that hypoxia can promote chondrogenesis of human bone marrow derived mesenchymal stem cells (hMSCs) in monolayer cultures. However, the direct impact of oxygen tension on hMSC differentiatio...
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Article
Clinical analysis of 73 cases of intraspinal nerve sheath tumor
Seventy-three patients with spinal nerve sheath tumor who were surgically treated in our hospital during the years 2004–2010 were retrospectively reviewed with respect to recovery of neurological function, rec...
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Article
Pericryptal fibroblast sheath in intestinal metaplasia, dysplasia and carcinoma of the stomach
To investigate the existence of pericryptal fibroblasts sheath (PCFS) in normal gastric mucosa, intestinal metaplasia (IM), indefinite for dysplasia (I-Dys), low grade dysplasia (L-Dys), high grade dysplasia (...
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Article
Medical resource utilizations and economic burden in Chinese cancer patients with chemotherapy-induced anemia: A populational database study
Most of published studies emphasized the medical cost of treating chemotherapy-induced anemia (CIA) by using specific agents, for example, epoetin α, epoetin β, darbepoetin α or combined with red blood cell tr...