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  1. No Access

    Article

    Tracking cognitive trajectories in older survivors of COVID-19 up to 2.5 years post-infection

    Emerging evidence suggests that neurological and other post-acute sequelae of COVID-19 can persist beyond or develop following SARS-CoV-2 infection. However, the long-term trajectories of cognitive change afte...

    Yu-Hui Liu, Quan-**n Wu, Qing-Hua Wang, Qiao-Feng Zhang, Yi Tang, Di Liu in Nature Aging (2024)

  2. Article

    Open Access

    Genome-wide analysis and expression profiling of the HD-ZIP gene family in kiwifruit

    The homeodomain-leucine zipper (HD-Zip) gene family plays a pivotal role in plant development and stress responses. Nevertheless, a comprehensive characterization of the HD-Zip gene family in kiwifruit has bee...

    Kai-yu Ye, Jie-wei Li, Fa-ming Wang, Jian-you Gao, Cui-xia Liu in BMC Genomics (2024)

  3. Article

    Open Access

    Lactobacillus rhamnosus GG ameliorates hyperuricemia in a novel model

    Hyperuricemia (HUA) is a metabolic syndrome caused by abnormal purine metabolism. Although recent studies have noted a relationship between the gut microbiota and gout, whether the microbiota could ameliorate ...

    Yang Fu, Yong-Song Chen, Dai-Yang **a, **ao-Dan Luo in npj Biofilms and Microbiomes (2024)

  4. Article

    Open Access

    IP3R2-mediated Ca2+ release promotes LPS-induced cardiomyocyte pyroptosis via the activation of NLRP3/Caspase-1/GSDMD pathway

    Pyroptosis plays a crucial role in sepsis, and the abnormal handling of myocyte calcium (Ca2+) has been associated with cardiomyocyte pyroptosis. Specifically, the inositol 1,4,5-trisphosphate receptor type 2 (IP...

    Qing-Rui Wu, Hui Yang, Hui-Dan Zhang, Yong-Jiang Cai in Cell Death Discovery (2024)

  5. No Access

    Article

    Gut commensal Christensenella minuta modulates host metabolism via acylated secondary bile acids

    A strong correlation between gut microbes and host health has been observed in numerous gut metagenomic cohort studies. However, the underlying mechanisms governing host–microbe interactions in the gut remain ...

    Chang Liu, Meng-Xuan Du, Li-Sheng **e, Wen-Zhao Wang, Bao-Song Chen in Nature Microbiology (2024)

  6. Article

    Open Access

    CircUBE2Q2 promotes differentiation of cattle muscle stem cells and is a potential regulatory molecule of skeletal muscle development

    The growth and development of muscle stem cells (MuSCs) are significant events known to affect muscle plasticity, disease, meat production, and meat quality, which involves the types and functions of mRNA and ...

    Rui-Men Zhang, Yu Pan, Chao-**a Zou, Qiang An, Juan-Ru Cheng, Peng-Ju Li in BMC Genomics (2022)

  7. No Access

    Article

    A robust mechanism for resetting juvenility during each generation in Arabidopsis

    Multicellular organisms undergo several developmental transitions during their life cycles. In contrast to animals, the plant germline is derived from adult somatic cells. As such, the juvenility of a plant mu...

    Jian Gao, Ke Zhang, Ying-Juan Cheng, Sha Yu, Guan-Dong Shang in Nature Plants (2022)

  8. Article

    Open Access

    Fibroblast CEBPD/SDF4 axis in response to chemotherapy-induced angiogenesis through CXCR4

    Cancer-associated fibroblasts (CAFs) play an essential role in supporting cancer progression. However, the details and consequent effects in response to the communication between CAFs and angiogenesis remain l...

    Jhih-Ying Chi, Yu-Wei Hsiao, Hai-Ling Liu, **n-Juan Fan in Cell Death Discovery (2021)

  9. Article

    Open Access

    Genome-wide methylation sequencing identifies progression-related epigenetic drivers in myelodysplastic syndromes

    The potential mechanism of myelodysplastic syndromes (MDS) progressing to acute myeloid leukemia (AML) remains poorly elucidated. It has been proved that epigenetic alterations play crucial roles in the pathog...

    **g-dong Zhou, Ting-juan Zhang, Zi-jun Xu, Zhao-qun Deng, Yu Gu in Cell Death & Disease (2020)

  10. Article

    Open Access

    ROR2 suppresses metastasis of prostate cancer via regulation of miR-199a-5p–PIAS3–AKT2 signaling axis

    Bones are the most common metastatic sites for prostate cancer (PCa). Receptor tyrosine kinase-like orphan receptor 2 (ROR2), a noncanonical Wnt receptor, plays crucial roles in skeletal morphogenesis, osteobl...

    Jen-Chih Tseng, Shih-Han Huang, Ching-Yu Lin, Bi-Juan Wang in Cell Death & Disease (2020)

  11. No Access

    Article

    NK cell reconstitution following unmanipulated HLA-mismatched/haploidentical transplantation compared with matched sibling transplantation

    Li-Juan Hu, Xun-Hong Cao, **ng-**ng Yu, Xue-Fei Liu in Science China Life Sciences (2020)

  12. Article

    Open Access

    New insight into the molecular mechanism of colour differentiation among floral segments in orchids

    An unbalanced pigment distribution among the sepal and petal segments results in various colour patterns of orchid flowers. Here, we explored this type of mechanism of colour pattern formation in flowers of the C...

    Bai-Jun Li, Bao-Qiang Zheng, Jie-Yu Wang, Wen-Chieh Tsai in Communications Biology (2020)

  13. Article

    Open Access

    A high-density genetic map developed by specific-locus amplified fragment (SLAF) sequencing and identification of a locus controlling anthocyanin pigmentation in stalk of Zicaitai (Brassica rapa L. ssp. chinensis var. purpurea)

    Caixin and Zicaitai (Brassica rapa) belong to Southern and Central China respectively. Zicaitai contains high amount of anthocyanin in leaf and stalk resulting to the purple color. Stalk is the major edible part ...

    Gui-Hua Li, Han-Cai Chen, Jia-Li Liu, Wen-Long Luo, Da-Sen **e, Shao-Bo Luo in BMC Genomics (2019)

  14. No Access

    Article

    A loop mediated isothermal amplification (LAMP) assay for rapid and reliable detection of Anguina wevelli, a grass parasitic nematode

    Anguina wevelli is a pathogenic grass parasitic nematode, however it is difficult to identify based simply on morphology. This study developed a loop-mediated isothermal amplification (LAMP) assa...

    Lu-zhen Yu, Shao-yi Song, Cui Yu, Long-jun Qi in European Journal of Plant Pathology (2018)

  15. No Access

    Article

    Cloning and characterization of Agp1, the gene encoding the small subunit of ADP-glucose pyrophosphorylase from wheat and its relatives

    ADP-glucose pyrophosphorylase (AGP) consists of two large (AGP-L) and two small (AGP-S) subunits; it regulates the limiting step in the biosynthesis of starch. Here, we isolated the full-length cDNA sequence o...

    **ao-Wei Zhang, Qing Wang, Ling-Ling Zhang, **ao-Juan Zhong, Qian-Tao Jiang in Biologia (2017)

  16. Article

    Open Access

    Diversity of methanogens in the hindgut of captive white rhinoceroses, Ceratotherium simum

    The white rhinoceros is on the verge of extinction with less than 20,200 animals remaining in the wild. In order to better protect these endangered animals, it is necessary to better understand their digestive...

    Yu-heng Luo, André-Denis G Wright, You-long Li, Hua Li, Qi-hong Yang in BMC Microbiology (2013)

  17. No Access

    Article

    The effects of Bt Cry1Ah toxin on worker honeybees (Apis mellifera ligustica and Apis cerana cerana)

    We conducted feeding trials in a laboratory setting to test for possible adverse effects of Cry1Ah toxin mixed thoroughly into sugar syrup (60% w/v sucrose solution) at three concentrations (10 μg/mL, 10 ng/mL, a...

    **-Li Dai, Wei Zhou, Jie Zhang, Wei-Yu Jiang, Qiang Wang, Hong-Juan Cui in Apidologie (2012)

  18. Article

    Open Access

    Giant panda BAC library construction and assembly of a 650-kb contig spanning major histocompatibility complex class II region

    Giant panda is rare and endangered species endemic to China. The low rates of reproductive success and infectious disease resistance have severely hampered the development of captive and wild populations of th...

    Chang-Jun Zeng, Hui-Juan Pan, Shao-Bin Gong, Jian-Qiu Yu, Qiu-Hong Wan in BMC Genomics (2007)

  19. No Access

    Article

    Assembling zwitterionic, water-soluble porphyrin and its biological studies

    A kind of zwitterionic water-soluble porphyrin 5-(N-trimethyl-4-aminiumphenyl)-10, 15, 20-tri (4-sulfonatephenyl) porphyrin trisammonium salt, has been synthesized. Its biological studies, interactions with DN...

    Chen Zhi-hang, Chen Bo, Lu Zhe-xue in Wuhan University Journal of Natural Scienc… (2005)