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  1. No Access

    Article

    Immunotherapy of tumors with xenogeneic endothelial cells as a vaccine

    The breaking of immune tolerance against autologous angiogenic endothelial cells should be a useful approach for cancer therapy. Here we show that immunotherapy of tumors using fixed xenogeneic whole endotheli...

    Yu-quan Wei, Qing-ru Wang, **a Zhao, Li Yang, Ling Tian, You Lu in Nature Medicine (2000)

  2. No Access

    Article

    Secreted Expression and Purification of Dengue 2 Virus Full-length Nonstructural Glycoprotein NS1 in Pichia. pastoris

    The dengue 2 virus (DEN-2) RNA (NGC strain) was used as a substrate to produce DNA clones of the full-length NS1 genes via reverse transcriptase synthesis of cDNA followed by polymerase chain reaction amplific...

    Jun-mei Zhou, Yun-xia Tang, Dan-yun Fang, **g-jiao Zhou, Yu Liang in Virus Genes (2006)

  3. Article

    Hypoxia reoxygenation induces premature senescence in neonatal SD rat cardiomyocytes

    To investigate whether hypoxia reoxygenation induces premature senescence in neonatal Sprague-Dawley (SD) rat cardiomyocytes.

    Feng-xiang Zhang, Ming-long Chen, Qi-jun Shan, Jian-gang Zou in Acta Pharmacologica Sinica (2007)

  4. No Access

    Article

    Genomic analysis of a Chinese isolate of Getah-like virus and its phylogenetic relationship with other Alphaviruses

    An alphavirus, M-1 strain, was isolated from a pool of culicine mosquitoes collected in Hainan island of China during an arbovirus survey in 1964. In the present study, we determined the complete nucleotide seque...

    **-Sheng Wen, Wen-Zhong Zhao, Jian-Wei Liu, Hong Zhou, Jian-** Tao in Virus Genes (2007)

  5. No Access

    Article

    An age-dependent proliferation is involved in the postnatal development of interstitial cells of Cajal in the small intestine of mice

    This paper aimed at investigating the alterations in interstitial cells of Cajal (ICCs) in the murine small intestine from 0-day to 56-day post-partum (P0–P56) by immunohistochemistry. The Kit+ ICCs, which were s...

    Feng Mei, Jiang Zhu, Sheng Guo, De-shan Zhou, Juan Han in Histochemistry and Cell Biology (2009)

  6. Article

    Infection and replication of avian influenza H5N1 virus in an infected human

    The highly pathogenic avian influenza H5N1 viruses usually cause severe diseases and high mortality in infected humans. However, the tissue tropism and underlying pathogenesis of H5N1 virus infection in humans...

    **g-Jiao Zhou, Dan-Yun Fang, Jie Fu, Jiang Tian, Jun-Mei Zhou, Hui-Jun Yan in Virus Genes (2009)

  7. Article

    The proteomic analysis of human neonatal umbilical cord serum by mass spectrometry

    To investigate the proteome composition and function of human neonatal arterial umbilical cord.

    Hong-juan Song, ** Zhang, Xue-jiang Guo, Lian-ming Liao in Acta Pharmacologica Sinica (2009)

  8. No Access

    Article

    Effects of Differentiated Versus Undifferentiated Adipose Tissue-derived Stromal Cell Grafts on Functional Recovery After Spinal Cord Contusion

    Controversies exist concerning the need for mesenchymal stromal cells (MSCs) to be transdifferentiated prior to their transplantation. In the present study, we compared the results of grafting into the rat con...

    Hong-Tian Zhang, Jie Luo, Li-Sen Sui, Xu Ma in Cellular and Molecular Neurobiology (2009)

  9. No Access

    Article

    Effects of sevoflurane preconditioning and postconditioning on rat myocardial stunning in ischemic reperfusion injury

    Ischemic preconditioning and postconditioning distinctly attenuate ventricular arrhythmia after ischemia without affecting the severity of myocardial stunning. Therefore, we report the effects of sevoflurane p...

    An-lu Dai, Li-hua Fan, Feng-jiang Zhang in Journal of Zhejiang University SCIENCE B (2010)

  10. No Access

    Article

    Sevoflurane postconditioning reduces myocardial reperfusion injury in rat isolated hearts via activation of PI3K/Akt signaling and modulation of Bcl-2 family proteins

    Sevoflurane postconditioning reduces myocardial infarct size. The objective of this study was to examine the role of the phosphatidylinositol-3-kinase (PI3K)/Akt pathway in anesthetic postconditioning and to d...

    Li-na Yu, **g Yu, Feng-jiang Zhang in Journal of Zhejiang University SCIENCE B (2010)

  11. Article

    Open Access

    Neck dissection and post-operative chemotherapy with dimethyl triazeno imidazole carboxamide and cisplatin protocol are useful for oral mucosal melanoma

    Oral mucosal melanoma (OMM) is a clinically rare disease with poor prognosis. Various treatment methods have been investigated with the aim of improving the prognosis. This study aimed to analyze the data of a...

    ** Yang, Guo-xin Ren, Chen-** Zhang, Guo-yu Zhou, Yong-jie Hu, Wen-jun Yang in BMC Cancer (2010)

  12. Article

    Sorafenib extends the survival time of patients with multiple recurrences of hepatocellular carcinoma after liver transplantation

    To determine the efficacy and toxicities of sorafenib in the treatment of patients with multiple recurrences of hepatocellular carcinoma (HCC) after liver transplantation in a Chinese population.

    Wei-feng Tan, Zhi-quan Qiu, Yong Yu, Rong-zheng Ran, Bing Yi in Acta Pharmacologica Sinica (2010)

  13. No Access

    Article

    Construction, purification, and evaluation of multivalent DNA vaccine against Schistosoma japonicum

    DNA vaccine encoding a multivalent antigen is a novel approach of protective immunization. Four Schistosoma japonicum candidate antigen genes, glyceraldehyde-3-phosphate dehydrogenase (SjGAPDH), 23 kDa transmembr...

    Lu Zhu, Hai-Feng Liu, Ming-Bo Lu, Quan-Ke Long, You-En Shi in Parasitology Research (2011)

  14. Article

    Open Access

    The abundance and host-seeking behavior of culicine species (Diptera: Culicidae) and Anopheles sinensis in Yongcheng city, people's Republic of China

    The knowledge of mosquito species diversity and the level of anthropophily exhibited by each species in a region are of great importance to the integrated vector control. Culicine species are the primary vecto...

    **ao-Bo Liu, Qi-Yong Liu, Yu-Hong Guo, **g-Yi Jiang, Dong-Sheng Ren in Parasites & Vectors (2011)

  15. No Access

    Article

    Genome-wide association study identifies a susceptibility locus for schizophrenia in Han Chinese at 11p11.2

    Dai Zhang and colleagues report a genome-wide association study for schizophrenia in the Han Chinese population. They identify a new susceptibility locus at 11p11.2 and also identify a locus at 6p21-22.1 in th...

    Wei-Hua Yue, Hai-Feng Wang, Liang-Dan Sun, Fu-Lei Tang, Zhong-Hua Liu in Nature Genetics (2011)

  16. Article

    Open Access

    Beneficial effects of non-matched allogeneic cord blood mononuclear cells upon patients with idiopathic osteoporosis

    Immunological arguments and historical examples have shown that treatment with cord blood for non-hematopoietic activities, such as growth factor production and stimulation of angiogenesis, may not require mat...

    Jun Li, Li Zhang, Liang Zhou, Zheng-** Yu, Feng Qi in Journal of Translational Medicine (2012)

  17. Article

    Open Access

    Vector capacity of Anopheles sinensis in malaria outbreak areas of central China

    Both falciparum and vivax malaria were historically prevalent in China with high incidence. With the control efforts, the annual incidence in the whole country has reduced to 0.0001% except in some areas in th...

    Jia-Yun Pan, Shui-Sen Zhou, **ang Zheng, Fang Huang, Duo-Quan Wang in Parasites & Vectors (2012)

  18. No Access

    Article

    Different effects of ERβ and TROP2 expression in Chinese patients with early-stage colon cancer

    Estrogen receptor beta (ERβ) and TROP2 expressed in colon carcinoma and might play an important role there. We explored the relationship of ERβ and TROP2 expression with the prognosis of early-stage colon canc...

    Yu-**g Fang, Guo-Qiang Wang, Zhen-Hai Lu, Lin Zhang, Ji-Bin Li in Tumor Biology (2012)

  19. No Access

    Article

    A clinical study on regional lymphatic chemotherapy using an activated carbon nanoparticle–epirubicin in patients with breast cancer

    The purpose of this study was to understand the short-term therapeutic effects of an activated carbon nanoparticle–epirubicin suspension for regional lymphatic chemotherapy in patients with breast cancer. One ...

    Qian Yang, **ao-dong Wang, Jie Chen, Chun-xiang Tian, Hong-jiang Li in Tumor Biology (2012)

  20. No Access

    Article

    Genetic variants in STAT4 and HLA-DQ genes confer risk of hepatitis B virus–related hepatocellular carcinoma

    Long Yu and colleagues report a genome-wide association study for hepatitis B virus–related hepatocellular carcinoma (HBV-HCC). They report that genetic variants in STAT4 and HLA-DQ genes confer risk of HBV-HCC.

    De-Ke Jiang, Jielin Sun, Guangwen Cao, Yao Liu, Dongxin Lin, Yu-Zhen Gao in Nature Genetics (2013)

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