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  1. No Access

    Article

    The dysfunction of BP180/collagen XVII in keratinocytes promotes melanoma progression

    BP180, also termed collagen XVII, is a hemidesmosomal transmembrane glycoprotein expressed in basal keratinocytes, and functions as a cell–matrix adhesion molecule in the dermal–epidermal junction of the skin....

    Bin-** Hwang, Yang Zhang, Jaime M. Brozowski, Zhen Liu, Susan Burette… in Oncogene (2019)

  2. No Access

    Article

    Androgen dihydrotestosterone (DHT) promotes the bladder cancer nuclear AR-negative cell invasion via a newly identified membrane androgen receptor (mAR-SLC39A9)-mediated Gαi protein/MAPK/MMP9 intracellular signaling

    While androgens may function via nuclear androgen receptor (nAR) to increase bladder cancer (BCa) progression, the impact of androgens on muscle invasive BCa, which contains nearly 80% nAR-negative cells, rema...

    **bo Chen, Fuju Chou, Shuyuan Yeh, Zhenyu Ou, Chihrong Shyr, Chi** Huang… in Oncogene (2020)

  3. No Access

    Article

    Inflammation-induced JMJD2D promotes colitis recovery and colon tumorigenesis by activating Hedgehog signaling

    Histone demethylase JMJD2D can promote gene expression by specifically demethylating H3K9me2/3. The role of JMJD2D in colitis and colitis-associated colorectal cancer (CRC) progression remains unclear. Here, w...

    Minghui Zhuo, Wenbo Chen, Shaohui Shang, Peng Guo, Kesong Peng, Ming Li… in Oncogene (2020)