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Article
Costunolide attenuates LPS-induced inflammation and lung injury through inhibiting IKK/NF-κB signaling
Inflammation is an important pathological process of many acute and chronic diseases, such as sepsis, arthritis, and cancer. Many factors can lead to an inflammatory state of the body, among which bacterial in...
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Article
Open AccessChalcone-derivative L6H21 attenuates the OVA-induced asthma by targeting MD2
Asthma represents a significant global challenge that affects individuals across all age groups and imposes substantial social and economic burden. Due to heterogeneity of the disease, not all patients obtain ...
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Article
Open AccessEffects of COVID-19 infection in patients with autoimmune pulmonary alveolar proteinosis: a single-center study
Autoimmune pulmonary alveolar proteinosis (aPAP) is a rare interstitial lung disease. COVID-19 is associated with worse prognosis in previous lung diseases patients. But the prognosis of aPAP patients after in...
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Article
Open AccessComprehensive evaluation of similarity between synthetic and real CT images for nasopharyngeal carcinoma
Although magnetic resonance imaging (MRI)-to-computed tomography (CT) synthesis studies based on deep learning have significantly progressed, the similarity between synthetic CT (sCT) and real CT (rCT) has onl...
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Article
Social Support and Left-Behind Children’s Social Adaptation: The Mediating Role of Self-Esteem
The mechanism by which social support contributes to the social adaptation of left-behind children (LBC) in mainland China remains unclear. This study aimed to investigate the direct effect of social support ...
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Article
Open AccessPrior information guided auto-segmentation of clinical target volume of tumor bed in postoperative breast cancer radiotherapy
Accurate delineation of clinical target volume of tumor bed (CTV-TB) is important but it is also challenging due to surgical effects and soft tissue contrast. Recently a few auto-segmentation methods were deve...
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Article
Open AccessEnvironmental Risk Factors, Protective Factors, and Biomarkers for Allergic Rhinitis: A Systematic Umbrella Review of the Evidence
Many potential environmental risk factors, protective factors, and biomarkers of AR have been published, but so far, the strength and consistency of their evidence are unclear. We conducted a comprehensive rev...
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Article
Open AccessNetwork module analysis and molecular docking-based study on the mechanism of astragali radix against non-small cell lung cancer
Most lung cancer patients worldwide (stage IV non-small cell lung cancer, NSCLC) have a poor survival: 25%-30% patients die < 3 months. Yet, of those surviving > 3 months, 10%-15% patients survive (very) long....
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Article
An algebraic projection procedure for construction of the basis vectors of irreducible representations of U(4) in the Su \(_{S}\) (2) \(\otimes \) su \(_{T}\) (2) basis
An effective algebraic spin–isospin projection procedure for constructing basis vectors of irreducible representations of U(4) \(\supset \) ...
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Article
Open AccessImproving accelerated 3D imaging in MRI-guided radiotherapy for prostate cancer using a deep learning method
This study was to improve image quality for high-speed MR imaging using a deep learning method for online adaptive radiotherapy in prostate cancer. We then evaluated its benefits on image registration.
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Article
LncRNA HCP5 acts as a miR-128-3p sponge to promote the progression of multiple myeloma through activating Wnt/β‐catenin/cyclin D1 signaling via PLAGL2
Although long non-coding RNA (lncRNA) HCP plays essential roles in human cancers, its function and mechanism in multiple myeloma (MM) have not crystallized.
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Article
Numerical study on hydrodynamics of two types of unsteady bubbles in shear-thinning liquids
A volume of fluid method combined with an adaptive grid method was used to study the influence of Galilei (Ga) and Eötvös (Eo) numbers and characteristic parameters (such as rheological index (n) and characterist...
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Article
Open AccessInterleukin-35 promotes Breg expansion and interleukin-10 production in CD19+ B cells in patients with ankylosing spondylitis
IL-35 is a potent immunosuppressive and anti-inflammatory cytokine, consisting of a p35 subunit and an Epstein–Barr virus–induced gene 3 (EBI3) subunit, which suppresses CD4+ effector T cell proliferation and pro...
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Article
Open AccessApplication of piecewise VMAT technique to whole-brain radiotherapy with simultaneous integrated boost for multiple metastases
This study implemented a piecewise volumetric modulated arc therapy (P-VMAT) for realizing whole-brain radiation therapy (WBRT) with simultaneous integrated boost (SIB) for multiple brain metastases (> 40 meta...
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Article
Open AccessApplying pytorch toolkit to plan optimization for circular cone based robotic radiotherapy
Robotic linac is ideally suited to deliver hypo-fractionated radiotherapy due to its compact head and flexible positioning. The non-coplanar treatment space improves the delivery versatility but the complexity...
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Article
Four-Dimensional Cone-Beam Computed Tomography Image Compression Using Video Encoder for Radiotherapy
Four dimensional cone-beam computed tomography (4D-CBCT) images were widely used for patient positing and target localization in radiotherapy. As consisting of multiple CBCT sets, it needs more time and space ...
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Article
Open AccessProton-assisted electron transfer and hydrogen-atom diffusion in a model system for photocatalytic hydrogen production
Solar energy can be converted into chemical energy by photocatalytic water splitting to produce molecular hydrogen. Details of the photo-induced reaction mechanism occurring on the surface of a semiconductor a...
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Article
Open AccessSearching for a \(D {\bar{D}}\) bound state with the \(\psi (3770) \rightarrow \gamma D^0 {\bar{D}}^0\) decay
We perform a calculation of the mass distribution in the \(\psi (3770) \rightarrow \gamma D {\bar{D}}\)ψ(3770)→γDD¯ decay, studying both the \(D^+ D^- \)D+D- and \(D^0 {\bar{D}}^0 \)D0D¯0 decays. The electromagne...
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Article
Meson exchange between initial and final state and the \(R_D\) ratio in the \(\bar{B} \rightarrow D \bar{\nu } \ell (\bar{\nu }_\tau \tau )\) reactions
We perform a calculation of the strong interaction effects between the B and D mesons in the \(\bar{B} \rightarrow D \bar{\nu } \ell \)B¯→Dν¯ℓ reaction, as a crossing process of reactions with BD in the final sta...
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Article
Open AccessNational survey of patient specific IMRT quality assurance in China
To analyze and present the China’s national survey on patient-specific IMRT quality assurance (QA).
