20 Result(s)
within
**nJie Jiang
Science, Humanities and Social Sciences, multidisciplinary
-
Article
Open AccessDevelopment and validation of a novel immune-related prognostic signature in lung squamous cell carcinoma patients
Lung Squamous Cell Carcinoma (LUSC) is an aggressive malignancy with limited therapeutic options. The response to immune therapy is a determining factor for the prognosis of LUSC patients. This study aimed to ...
-
Article
Open AccessGenomic basis of the giga-chromosomes and giga-genome of tree peony Paeonia ostii
Tree peony (Paeonia ostii) is an economically important ornamental plant native to China. It is also notable for its seed oil, which is abundant in unsaturated fatty acids such as α-linolenic acid (ALA). Here, we...
-
Article
Open AccessDigital quantum simulation of Floquet symmetry-protected topological phases
Quantum many-body systems away from equilibrium host a rich variety of exotic phenomena that are forbidden by equilibrium thermodynamics. A prominent example is that of discrete time crystals1–8, in which time-tr...
-
Article
Open AccessModulating Pt-O-Pt atomic clusters with isolated cobalt atoms for enhanced hydrogen evolution catalysis
Platinum is the most efficient catalyst for hydrogen evolution reaction in acidic conditions, but its widespread use has been impeded by scarcity and high cost. Herein, Pt atomic clusters (Pt ACs) containing P...
-
Article
Author Correction: A graph placement methodology for fast chip design
-
Article
Open AccessEBV miRNAs BART11 and BART17-3p promote immune escape through the enhancer-mediated transcription of PD-L1
Epstein-Barr virus (EBV) is reportedly the first identified human tumor virus, and is closely related to the occurrence and development of nasopharyngeal carcinoma (NPC), gastric carcinoma (GC), and several ly...
-
Article
Open AccessSingle cell atlas for 11 non-model mammals, reptiles and birds
The availability of viral entry factors is a prerequisite for the cross-species transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Large-scale single-cell screening of animal cells c...
-
Article
Open AccessWhole-exome sequencing of alpha-fetoprotein producing gastric carcinoma reveals genomic profile and therapeutic targets
Alpha-fetoprotein producing gastric carcinoma (AFPGC) is a rare and aggressive subtype of gastric cancer. However, little is known about the genomic features of this disease. We perform whole-exome sequencing ...
-
Article
A graph placement methodology for fast chip design
Chip floorplanning is the engineering task of designing the physical layout of a computer chip. Despite five decades of research1, chip floorplanning has defied automation, requiring months of intense effort by p...
-
Article
Open AccessIrrelevance of linear controllability to nonlinear dynamical networks
There has been tremendous development in linear controllability of complex networks. Real-world systems are fundamentally nonlinear. Is linear controllability relevant to nonlinear dynamical networks? We ident...
-
Article
Open AccessGenomic characterization of genes encoding histone acetylation modulator proteins identifies therapeutic targets for cancer treatment
A growing emphasis in anticancer drug discovery efforts has been on targeting histone acetylation modulators. Here we comprehensively analyze the genomic alterations of the genes encoding histone acetylation m...
-
Article
Open Access(S)-Oxiracetam is the Active Ingredient in Oxiracetam that Alleviates the Cognitive Impairment Induced by Chronic Cerebral Hypoperfusion in Rats
Chronic cerebral hypoperfusion is a pathological state that is associated with the cognitive impairments in vascular dementia. Oxiracetam is a nootropic drug that is commonly used to treat cognitive deficits o...
-
Article
Open AccessHIV-1 CRF01_AE strain is associated with faster HIV/AIDS progression in Jiangsu Province, China
The goal of this study was to assess risk factors associated with HIV/AIDS progression. Between May 2007 and December 2014, 114 subjects were enrolled in Wuxi City and examined every 6 months. The pol gene sequen...
-
Article
Open AccessA new avenue for obtaining insight into the functional characteristics of long noncoding RNAs associated with estrogen receptor signaling
Estrogen receptor signalling plays important regulatory roles in multiple mammalian physiological processes. Dysregulation of estrogen receptor (ER) expression and/or its associated signalling pathway is stron...
-
Article
Open AccessNeuroprotective Effects of A Standardized Flavonoid Extract of Safflower Against Neurotoxin-Induced Cellular and Animal Models of Parkinson’s Disease
Safflower has long been used to treat cerebrovascular diseases in China. We previously reported that kaempferol derivatives of safflower can bind DJ-1, a protein associated with Parkinson’s disease (PD) and fl...
-
Article
Open AccessConstruction and analysis of dynamic transcription factor regulatory networks in the progression of glioma
The combinatorial cross-regulation of transcription factors (TFs) plays an important role in cellular identity and function; however, the dynamic regulation of TFs during glioma progression remains largely unk...
-
Article
Open AccessPreliminary identification of palaeofloods with the alkane ratio C31/C17 and their potential link to global climate changes
A major challenge in palaeohydrology is the extraction of continuous palaeoflood information from geophysical records. A high-resolution sediment core off the Minjiang estuary area in the Taiwan Strait, SE Chi...
-
Article
Modified fiber qualities of the transgenic cotton expressing a silkworm fibroin gene
A silkworm gene for fibroin was introduced into the upland cotton WC line by Agrobacterium-mediated transformation. PCR detection for fibroin, nptII and gus genes, Kanamycin (Km)-resistance analysis and GUS-histo...
-
Article
AverageB-width and infinite-dimensionalG-width of some smooth function classes on the line
The exact values of average σ-B width and infinite dimensional σ-G width of Sobolev classB r ⌍ (R) in the metric Lp(R) (1≤p<∞) are obtained and...
-
Article
Average widths and optimal recovery of multivariate Besov classes inL p (Rd)
Some weak asymptotic results for average δ -K width and average δ -L width of the isotropic Besov classes Sr p6B(R d), Sr p6b(Rd), and the aniwtropic Besov classes ...
