![Loading...](https://link.springer.com/static/c4a417b97a76cc2980e3c25e2271af3129e08bbe/images/pdf-preview/spacer.gif)
-
Article
Open AccessFerritinophagy: research advance and clinical significance in cancers
Ferritinophagy, a process involving selective autophagy of ferritin facilitated by nuclear receptor coactivator 4 (NCOA4), entails the recognition of ferritin by NCOA4 and subsequent delivery to the autophagos...
-
Article
Open AccessA comprehensive assessment of exome capture methods for RNA sequencing of formalin-fixed and paraffin-embedded samples
RNA-Seq analysis of Formalin-Fixed and Paraffin-Embedded (FFPE) samples has emerged as a highly effective approach and is increasingly being used in clinical research and drug development. However, the process...
-
Article
Open AccessPotential crop yield gains under intensive soybean/maize intercrop** in China
Intensive soybean/maize intercrop**, a specific form of intercrop**, holds promise in addressing the challenges posed by increasing food demands, diminishing cropland areas, deteriorating soil quality, and...
-
Article
Open AccessNitric oxide-dependent immunosuppressive function of thymus-derived mesenchymal stromal/stem cells
The thymus is required for T cell development and the formation of the adaptive immunity. Stromal cells, which include thymic epithelial cells (TECs) and mesenchymal stromal cells (MSCs), are essential for thy...
-
Article
Open AccessThe space cold atom interferometer for testing the equivalence principle in the China Space Station
The precision of the weak equivalence principle (WEP) test using atom interferometers (AIs) is expected to be extremely high in microgravity environment. The microgravity scientific laboratory cabinet (MSLC) i...
-
Article
Correction to: HYOU1 promotes cell proliferation, migration, and invasion via the PI3K/AKT/FOXO1 feedback loop in bladder cancer
-
Article
Open AccessMesenchymal stem cells alleviate systemic sclerosis by inhibiting the recruitment of pathogenic macrophages
Systemic sclerosis (SSc) is a recalcitrant autoimmune disease for which there is no cure. Mesenchymal stem cell (MSC)-based treatment has emerged as a promising therapeutic option for several autoimmune diseas...
-
Article
Open AccessMesenchymal stem/stromal cells primed by inflammatory cytokines alleviate psoriasis-like inflammation via the TSG-6-neutrophil axis
Psoriasis is currently an incurable skin disorder mainly driven by a chronic inflammatory response. We found that subcutaneous application of umbilical cord- derived mesenchymal stem/stromal cells (MSCs) prime...
-
Article
Open AccessRegulatory pathways and drugs associated with ferroptosis in tumors
Ferroptosis is a type of cell death that depends on iron and reactive oxygen species (ROS). The accumulation of iron and lipid peroxidation primarily initiates oxidative membrane damage during ferroptosis. The...
-
Article
Open AccessEfficient Breeding of Early-Maturing Rice Cultivar by Editing PHYC via CRISPR/Cas9
-
Article
Open AccessRGG1, Involved in the Cytokinin Regulatory Pathway, Controls Grain Size in Rice
Heterotrimeric GTP binding proteins (G proteins) and cytokinin play important roles in regulating plant growth and development. However, little is known about the mechanism by which they coordinate the regulat...
-
Article
Open AccessLncRNA LINC00472 regulates cell stiffness and inhibits the migration and invasion of lung adenocarcinoma by binding to YBX1
There is increasing evidence that long non-coding RNAs (lncRNAs) play important roles in human tumorigenesis. By using publicly available expression profiling data from lung adenocarcinoma and integrating bioi...
-
Article
Open AccessClonal derivation of white and brown adipocyte progenitor cell lines from human pluripotent stem cells
The role of brown fat in non-shivering thermogenesis and the discovery of brown fat depots in adult humans has made it the subject of intense research interest. A renewable source of brown adipocyte (BA) proge...
-
Article
Open AccessWeighted gene co-expression network analysis of expression data of monozygotic twins identifies specific modules and hub genes related to BMI
The therapeutic management of obesity is challenging, hence further elucidating the underlying mechanisms of obesity development and identifying new diagnostic biomarkers and therapeutic targets are urgent and...
-
Article
Open AccessIntramuscular injection of human umbilical cord-derived mesenchymal stem cells improves cardiac function in dilated cardiomyopathy rats
Stem cells provide a promising candidate for the treatment of the fatal pediatric dilated cardiomyopathy (DCM). This study aimed to investigate the effects of intramuscular injection of human umbilical cord-de...
-
Article
A novel xeno-free and feeder-cell-free system for human pluripotent stem cell culture
While human induced pluripotent stem cells (hiPSCs) have promising applications in regenerative medicine, most of the hiPSC lines available today are not suitable for clinical applications due to contamination...
-
Article
Direct differentiation of atrial and ventricular myocytes from human embryonic stem cells by alternating retinoid signals
Although myocyte cell transplantation studies have suggested a promising therapeutic potential for myocardial infarction, a major obstacle to the development of clinical therapies for myocardial repair is the ...
-
Chapter and Conference Paper
Research of RFID Middleware in Precision Feeding System of Breeder Swine
In Precision Feeding System of Breeder Swine, RFID is used to collect some important information about the body status of individual swine, IT is banded together with the adjusting of nutrition model, so as to...