319 Result(s)
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Article
Adaptation of a prey population to increasing predation risks
To test the hypotheses that multigenerational predation risk favors clones with longer postero-lateral spines and a larger body, and that fitness consequences of selection depend on both tested fitness variabl...
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Plasma Ionomic Profile and Interaction Patterns in Coronary Artery Disease Patients
Humans are exposed to various chemical elements that have been associated with the development and progression of diseases such as coronary artery disease (CAD). Unlike previous research, we employed a multi-e...
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Open AccessBacterial c-di-GMP triggers metamorphosis of mussel larvae through a STING receptor
Bacteria induced metamorphosis observed in nearly all marine invertebrates. However, the mechanism of bacteria regulating the larvae-juvenile metamorphosis remains unknown. Here, we test the hypothesis that c-...
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Open AccessAMPK targets PDZD8 to trigger carbon source shift from glucose to glutamine
The shift of carbon utilization from primarily glucose to other nutrients is a fundamental metabolic adaptation to cope with decreased blood glucose levels and the consequent decline in glucose oxidation. AMP-...
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Effects of Spraying Allantoin at Different Stages on Inorganic Nitrogen Assimilation, Endogenous Hormones, Yield, and Quality of Sugar Beet in Saline-Alkali Land
Soil salinization profoundly impacts the growth and development of sugar beet. As a urea cytokinin, allantoin effectively mitigates the adverse effects of salinity stress on plants. However, there has been lim...
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Open AccessIsochorismate synthase is required for phylloquinone, but not salicylic acid biosynthesis in rice
Salicylic acid (SA) is a phytohormone required for plant growth and defense signaling. There are two major SA biosynthesis pathways in plants: the isochorismate synthase (ICS) pathway and the phenylalanine amm...
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Open AccessAgrin-Lrp4 pathway in hippocampal astrocytes restrains development of temporal lobe epilepsy through adenosine signaling
Human patients often experience an episode of serious seizure activity, such as status epilepticus (SE), prior to the onset of temporal lobe epilepsy (TLE), suggesting that SE can trigger the development of ep...
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Chemical constituents from the aerial parts of Rhododendron thymifolium and its bioactivities against Tribolium castaneum, Lasioderma serricorne, and Ditylenchus destructor
This study investigated chemical compositions and biocidal activities from the aerial parts of Rhododendron thymifolium against Tribolium castaneum, Lasioderma serricorne, and Ditylenchus destructor. In total, 13...
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Article
Open AccessThe biomedical knowledge graph of symptom phenotype in coronary artery plaque: machine learning-based analysis of real-world clinical data
A knowledge graph can effectively showcase the essential characteristics of data and is increasingly emerging as a significant means of integrating information in the field of artificial intelligence. Coronary...
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Open AccessDrought response revealed by chromatin organization variation and transcriptional regulation in cotton
Cotton is a major world cash crop and an important source of natural fiber, oil, and protein. Drought stress is becoming a restrictive factor affecting cotton production. To facilitate the development of droug...
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Article
Identification and expression analysis of Jr4CLs gene family based on transcriptome and physiological data in walnut (Juglans regia)
Shoot shriveling severely threaten growth and development of deciduous trees in northern hemisphere, its essence is imbalance of water absorption and evaporation in the branches. In this study, the physiologic...
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Article
Mining, screening, and validation of cold-resistance molecular markers in Vitis vinifera L.
To address one of the main challenges restricting the development of global viticulture, it is imperative to breed high-quality and cold-resistant grape varieties. In this study, intraspecific cross-breeding w...
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Lactiplantibacillus plantarum RS20D Alleviates Male Reproductive Toxicity Induced by Pubertal Exposure to Di-n-butyl Phthalate and Mono-n-butyl Phthalate
Phthalate acid esters (PAEs) and their metabolites, such as di-n-butyl phthalate (DBP) and mono-n-butyl phthalate (MBP), are known to cause male reproductive damage. Lactiplantibacillus plantarum RS20D has demons...
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Open AccessKlotho exerts protection in chronic kidney disease associated with regulating inflammatory response and lipid metabolism
The anti-aging protein Klotho plays a protective role in kidney disease, but its potential as a biomarker for chronic kidney disease (CKD) is controversial. Additionally, the main pathways through which Klotho...
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Open AccessSugarcane borers: species, distribution, damage and management options
Lepidopteran borers stand out as the most destructive pests in sugarcane, leading to reductions in stalk weight, juice quality and sugar recovery. Presently, integrated pest management (IPM) systems are utiliz...
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SbMYC2 mediates jasmonic acid signaling to improve drought tolerance via directly activating SbGR1 in sorghum
SbMYC2 functions as a key regulator under JA signaling in enhancing drought tolerance of sorghum through direct activating SbGR1.
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Article
Endothelial extracellular vesicles induce acute lung injury via follistatin-like protein 1
Cardiopulmonary bypass has been speculated to elicit systemic inflammation to initiate acute lung injury (ALI), including acute respiratory distress syndrome (ARDS), in patients after cardiac surgery. We previ...
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Article
Initial Upper Palaeolithic material culture by 45,000 years ago at Shiyu in northern China
The geographic expansion of Homo sapiens populations into southeastern Europe occurred by ∼47,000 years ago (∼47 ka), marked by Initial Upper Palaeolithic (IUP) technology. H. sapiens was present in western Siber...
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Open AccessResistant starch intake facilitates weight loss in humans by resha** the gut microbiota
Emerging evidence suggests that modulation of gut microbiota by dietary fibre may offer solutions for metabolic disorders. In a randomized placebo-controlled crossover design trial (ChiCTR-TTRCC-13003333) in 3...
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Genomic study of PIFs in cotton and functional analysis of GhPIF4 in promoting cotton flowering
Cotton is the most important commercial crop in the production of fiber for the textile industry worldwide, and flowering time is an important agronomic trait for cotton production. Phytochrome interacting fac...