3 Result(s)
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Article
Open AccessDesign of a mutation-integrated trimeric RBD with broad protection against SARS-CoV-2
The continuous emergence of SARS-CoV-2 variants highlights the need of develo** vaccines with broad protection. Here, according to the immune-escape capability and evolutionary convergence, the representativ...
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Article
Open AccessHigh glucose induces Drp1-mediated mitochondrial fission via the Orai1 calcium channel to participate in diabetic cardiomyocyte hypertrophy
Mitochondrial dysfunction and impaired Ca2+ handling are involved in the development of diabetic cardiomyopathy (DCM). Dynamic relative protein 1 (Drp1) regulates mitochondrial fission by changing its level of ph...
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Article
Predicting intrinsic disorder in proteins: an overview
The discovery of intrinsically disordered proteins (IDP) (i.e., biologically active proteins that do not possess stable secondary and/or tertiary structures) came as an unexpected surprise, as the existence of...
