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  1. Article

    Open Access

    Histone deacetylase 3 promotes innate antiviral immunity through deacetylation of TBK1

    TANK-binding kinase 1 (TBK1), a core kinase of antiviral pathways, activates the production of interferons (IFNs). It has been reported that deacetylation activates TBK1; however, the precise mechanism still r...

    Jie-lin Tang, Qi Yang, Chong-hui Xu, He Zhao, Ya-ling Liu, Can-yu Liu… in Protein & Cell (2021)

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  2. Article

    Open Access

    High glucose induces Drp1-mediated mitochondrial fission via the Orai1 calcium channel to participate in diabetic cardiomyocyte hypertrophy

    Mitochondrial dysfunction and impaired Ca2+ handling are involved in the development of diabetic cardiomyopathy (DCM). Dynamic relative protein 1 (Drp1) regulates mitochondrial fission by changing its level of ph...

    Qing-Rui Wu, Dan-Lin Zheng, Pei-Ming Liu, Hui Yang, Lu-An Li… in Cell Death & Disease (2021)

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  3. No Access

    Article

    The formation of Ca2+ gradients at the cleavage furrows during cytokinesis of Zebrafish embryos

    In dividing embryos, a localized elevation in intracellular Ca2+ ([Ca2+]i) at the cleavage furrow has been shown to be essential for cytokinesis. However, the underlying mechanisms for generating and maintaining ...

    Yun-Bo Guo, Ya Wen, Wen-Xue Gao, **g-Chao Li, Peng Zhou… in Frontiers in Biology (2010)