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  1. Article

    Open Access

    Coordinated wound responses in a regenerative animal-algal holobiont

    Animal regeneration involves coordinated responses across cell types throughout the animal body. In endosymbiotic animals, whether and how symbionts react to host injury and how cellular responses are integrat...

    Dania Nanes Sarfati, Yuan Xue, Eun Sun Song, Ashley Byrne in Nature Communications (2024)

  2. Article

    Open Access

    An artificial protein modulator reprogramming neuronal protein functions

    Reversible protein phosphorylation, regulated by protein phosphatases, fine-tunes target protein function and plays a vital role in biological processes. Dysregulation of this process leads to aberrant post-tr...

    Peihua Lin, Bo Zhang, Hongli Yang, Shengfei Yang, Pengpeng Xue in Nature Communications (2024)

  3. Article

    Open Access

    Hydrogen bond unlocking-driven pore structure control for shifting multi-component gas separation function

    Purification of ethylene (C2H4) as the most extensive and output chemical, from complex multi-components is of great significance but highly challenging. Herein we demonstrate that precise pore structure tuning b...

    Rong Yang, Yu Wang, Jian-Wei Cao, Zi-Ming Ye, Tony Pham in Nature Communications (2024)

  4. Article

    Open Access

    Temporal dendritic heterogeneity incorporated with spiking neural networks for learning multi-timescale dynamics

    It is widely believed the brain-inspired spiking neural networks have the capability of processing temporal information owing to their dynamic attributes. However, how to understand what kind of mechanisms con...

    Hanle Zheng, Zhong Zheng, Rui Hu, Bo **ao, Yujie Wu, Fangwen Yu in Nature Communications (2024)

  5. Article

    Open Access

    The ELAVL3/MYCN positive feedback loop provides a therapeutic target for neuroendocrine prostate cancer

    Neuroendocrine prostate cancer is a rapidly progressive and lethal disease characterized by early visceral metastasis, poor prognosis, and limited treatment options. Uncovering the oncogenic mechanisms could l...

    Yiyi Ji, Weiwei Zhang, Kai Shen, Ruopeng Su, **nyu Liu, Zehua Ma in Nature Communications (2023)

  6. Article

    Open Access

    Quantum storage of entangled photons at telecom wavelengths in a crystal

    Quantum storage and distribution of entanglement are the key ingredients for realizing a global quantum internet. Compatible with existing fiber networks, telecom-wavelength entangled photons and corresponding...

    Ming-Hao Jiang, Wenyi Xue, Qian He, Yu-Yang An, **aodong Zheng in Nature Communications (2023)

  7. Article

    Open Access

    Revealing the role of interfacial water and key intermediates at ruthenium surfaces in the alkaline hydrogen evolution reaction

    Ruthenium exhibits comparable or even better alkaline hydrogen evolution reaction activity than platinum, however, the mechanistic aspects are yet to be settled, which are elucidated by combining in situ Raman...

    **ng Chen, **ao-Ting Wang, Jia-Bo Le, Shu-Min Li, Xue Wang in Nature Communications (2023)

  8. Article

    Open Access

    A ZFYVE21-Rubicon-RNF34 signaling complex promotes endosome-associated inflammasome activity in endothelial cells

    Internalization of complement membrane attack complexes (MACs) assembles NLRP3 inflammasomes in endothelial cells (EC) and promotes IL-β-mediated tissue inflammation. Informed by proteomics analyses of FACS-so...

    Xue Li, Quan Jiang, Guiyu Song, Mahsa Nouri Barkestani in Nature Communications (2023)

  9. Article

    Open Access

    Establishment and validation of a plasma oncofetal chondroitin sulfated proteoglycan for pan-cancer detection

    Various biomarkers targeting cell-free DNA (cfDNA) and circulating proteins have been tested for pan-cancer detection. Oncofetal chondroitin sulfate (ofCS), which distinctively modifies proteoglycans (PGs) of ...

    Pei-Fen Zhang, Zi-Yi Wu, Wen-Bin Zhang, Yong-Qiao He, Kexin Chen in Nature Communications (2023)

  10. Article

    Open Access

    Unraveling sulfur chemistry in interstellar carbon oxide ices

    Formyl radical (HCO•) and hydroxycarbonyl radical (HOCO•) are versatile building blocks in the formation of biorelevant complex organic molecules (COMs) in interstellar medium. Understanding the chemical pathw...

    **aolong Li, Bo Lu, Lina Wang, Junfei Xue, Bifeng Zhu in Nature Communications (2022)

  11. Article

    Open Access

    A spin-crossover framework endowed with pore-adjustable behavior by slow structural dynamics

    Host-guest interactions play critical roles in achieving switchable structures and functionalities in porous materials, but design and control remain challenging. Here, we report a two-dimensional porous magne...

    **-Peng Xue, Yang Hu, Bo Zhao, Zhi-Kun Liu, **g **e, Zi-Shuo Yao in Nature Communications (2022)

  12. Article

    Open Access

    Neural network-based prediction of the secret-key rate of quantum key distribution

    Numerical methods are widely used to calculate the secure key rate of many quantum key distribution protocols in practice, but they consume many computing resources and are too time-consuming. In this work, we...

    Min-Gang Zhou, Zhi-** Liu, Wen-Bo Liu, Chen-Long Li, Jun-Lin Bai in Scientific Reports (2022)

  13. Article

    Open Access

    Giant single-crystal-to-single-crystal transformations associated with chiral interconversion induced by elimination of chelating ligands

    Numerous single crystals that exhibit single-crystal-to-single-crystal (SCSC) transformations have been reported, and some of them show great promise for application to advanced adsorption materials, magnetic ...

    Yun Li, Bo Zhao, **-Peng Xue, **g **e, Zi-Shuo Yao, Jun Tao in Nature Communications (2021)

  14. Article

    Open Access

    Author Correction: BDNF contributes to IBS-like colonic hypersensitivity via activating the enteroglia-nerve unit

    Peng Wang, Chao Du, Fei-Xue Chen, Chang-Qing Li, Yan-Bo Yu, Ting Han in Scientific Reports (2021)

  15. Article

    A human neutralizing antibody targets the receptor-binding site of SARS-CoV-2

    An outbreak of coronavirus disease 2019 (COVID-19)13, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)4, has spread globally. Countermeasures are needed to treat and prevent further dissemi...

    Rui Shi, Chao Shan, **aomin Duan, Zhihai Chen, Peipei Liu, **wen Song, Tao Song in Nature (2020)

  16. Article

    Open Access

    Integrated omics in Drosophila uncover a circadian kinome

    Most organisms on the earth exhibit circadian rhythms in behavior and physiology, which are driven by endogenous clocks. Phosphorylation plays a central role in timing the clock, but how this contributes to ov...

    Chenwei Wang, Ke Shui, Shanshan Ma, Shaofeng Lin, Ying Zhang in Nature Communications (2020)

  17. Article

    Open Access

    Environmental remodeling of human gut microbiota and antibiotic resistome in livestock farms

    Anthropogenic environments have been implicated in enrichment and exchange of antibiotic resistance genes and bacteria. Here we study the impact of confined and controlled swine farm environments on temporal c...

    Jian Sun, **ao-** Liao, Alaric W. D’Souza, Manish Boolchandani in Nature Communications (2020)

  18. Article

    Open Access

    Reconstruction of the lncRNA-miRNA-mRNA network based on competitive endogenous RNA reveal functional lncRNAs in Cerebral Infarction

    Functioning as miRNA sponges, long non-coding RNA (lncRNA) exert its pharmacological action via regulating expression of protein-coding genes. However, the lncRNA-mediated ceRNA in cerebral Infarction (CI) rem...

    Jun-Bo Zou, Hong-Bo Chai, **ao-Fei Zhang, Dong-Yan Guo, Jia Tai in Scientific Reports (2019)

  19. Article

    Open Access

    Structural and functional analyses of hepatitis B virus X protein BH3-like domain and Bcl-xL interaction

    Hepatitis B virus (HBV) X protein, HBx, interacts with anti-apoptotic Bcl-2 and Bcl-xL proteins through its BH3-like motif to promote HBV replication and cytotoxicity. Here we report the crystal structure of H...

    Tian-Ying Zhang, Hong-Ying Chen, Jia-Li Cao, Hua-Long **ong in Nature Communications (2019)

  20. No Access

    Article

    A vitamin-C-derived DNA modification catalysed by an algal TET homologue

    Methylation of cytosine to 5-methylcytosine (5mC) is a prevalent DNA modification found in many organisms. Sequential oxidation of 5mC by ten-eleven translocation (TET) dioxygenases results in a cascade of add...

    Jian-Huang Xue, Guo-Dong Chen, Fuhua Hao, Hui Chen, Zhaoyuan Fang, Fang-Fang Chen in Nature (2019)

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