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  1. No Access

    Article

    Specific amino acid restriction inhibits attachment and spreading of human melanoma via modulation of the integrin/focal adhesion kinase pathway and actin cytoskeleton remodeling

    We had previously found that selective restriction of amino acids inhibits invasion of human A375 melanoma. Integrins, cell surface receptors for the components of extracellular matrix (ECM), are activated dur...

    Ya-Min Fu, Hui Zhang, Mingjie Ding, Yi-Qi Li, **ng Fu… in Clinical & Experimental Metastasis (2005)

  2. No Access

    Article

    Inhibition of B16BL6 melanoma invasion by tyrosine and phenylalanine deprivation is associated with decreased secretion of plasminogen activators and increased plasminogen activator inhibitors

    We previously found that dietary tyrosine (Tyr) and phenylalanine (Phe) limitation significantly decreased the metastatic phenotype of B16BL6 melanoma cells in vivo and decreased the in vitro invasion of these ce...

    Bertha A. Pelayo, Ya-Min Fu, Gary G. Meadows in Clinical & Experimental Metastasis (1999)