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    Article

    Diurnal Characteristics of the Orexin System Genes and Its Effects on Pathology at Early Stage in 3xTg-AD Mice

    Orexin and its receptors are closely related to the pathogenesis of Alzheimer’s disease (AD). Although the expression of orexin system genes under physiological condition has circadian rhythm, the diurnal char...

    **g Yin, Chun-Mei Tuo, Kai-Yue Yu, **ao-Hong Hu, Yan-Ying Fan in NeuroMolecular Medicine (2023)

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    Article

    PGC-1α Affects Epileptic Seizures by Regulating Mitochondrial Fusion in Epileptic Rats

    Background: Peroxisome proliferator-activated receptor γ coactivator-1α (PGC-1α), regulated by AMPK, is an important regulator of mitochondrial fusion. At present, whether the AMPK/PGC-1α signaling pathway regula...

    Dongxu Li, Linhai Zhang, **mei Tuo, Fan Zhang, Zhenzhen Tai in Neurochemical Research (2023)