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Article
H3N3 Approximate Formulae for Typical Fractional Derivatives
The existing numerical approximation formulae for two kinds of typical fractional derivatives—the exponential Caputo and Caputo-Hadamard derivatives both of order ...
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Article
Food-Pollen Cross-Reactivity and its Molecular Diagnosis in China
Plant-derived foods are one of the most common causative sources of food allergy in China, with a significant relationship to pollinosis. This review aims to provide a comprehensive overview of this food-polle...
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Article
Regulating NCOA4-Mediated Ferritinophagy for Therapeutic Intervention in Cerebral Ischemia-Reperfusion Injury
Ischemic stroke presents a global health challenge, necessitating an in-depth comprehension of its pathophysiology and therapeutic strategies. While reperfusion therapy salvages brain tissue, it also triggers ...
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Article
Improvement of Stachys sieboldii (Miq.) growth by virus elimination of shoot apices cultivated on media free of plant growth regulators
Chinese artichoke (Stachys sieboldii [Miq.]) is a popular healthcare food owing to its high contents of stachyose. Viral infections have caused the severe degeneration of germplasm in this plant species. An effic...
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Article
Open AccessUncovering the ferroptosis related mechanism of laduviglusib in the cell-type-specific targets of the striatum in Huntington’s disease
Huntington’s disease (HD) is a dominantly inherited neurodegenerative disorder featured by abnormal movements, arising from the extensive neuronal loss and glial dysfunction in the striatum. Although the cause...
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Article
Ceftazidime is a potential drug to inhibit cell proliferation by increasing cellular p27
The development of new therapeutic uses for existing drugs is important for the treatment of some diseases. Cephalosporin antibiotics stand as the most extensively utilized antibiotics in clinical practice, ef...
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Article
Cryo-EM structures of Smc5/6 in multiple states reveal its assembly and functional mechanisms
Smc5/6 is a member of the eukaryotic structural maintenance of chromosomes (SMC) family of complexes with important roles in genome maintenance and viral restriction. However, limited structural understanding ...
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Article
Design of energy management for composite energy storage system consisting of lithium battery and flywheel based on adaptive wavelet–fuzzy control strategy
Energy management is a key factor affecting the efficient distribution and utilization of energy for on-board composite energy storage system. For the composite energy storage system consisting of lithium batt...
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Article
Open AccessDeoxynivalenol induces m6A-mediated upregulation of p21 and growth arrest of mouse hippocampal neuron cells in vitro
Hippocampal neurons maintain the ability of proliferation throughout life to support neurogenesis. Deoxynivalenol (DON) is a mycotoxin that exhibits brain toxicity, yet whether and how DON affects hippocampal ...
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Article
Combination of HIFU with sulfur hexafluoride microbubbles in the treatment of solitary uterine fibroids: a systematic review and meta-analysis
To assess the efficacy and safety of sulfur hexafluoride microbubbles on ultrasound-guided high-intensity focused ultrasound (HIFU) ablation of uterine fibroids.
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Article
Chidamide inhibits cell glycolysis in acute myeloid leukemia by decreasing N6-methyladenosine-related GNAS-AS1
Acute myeloid leukemia (AML) is a hematopoietic malignancy. Chidamide has shown anti-cancer effect in different malignancies. The function of Chidamide in glycolysis in AML cells remains unclear.
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Article
Sea urchin-like CoTe-CoP heterostructure catalyst for efficient hydrogen evolution in all-pH range
The development of robust and pH-adaptable hydrogen evolution reaction (HER) catalysts is of great significance to achieve a mass-scale hydrogen production. The interface engineering is one of the most effecti...
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Article
Single-machine primary–secondary scheduling with total tardiness being the primary criterion
We study the single-machine primary–secondary scheduling problems in which the total tardiness is the primary criterion and the secondary criteria are the maximum lateness, the (weighted) number of tardy jobs,...
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Article
Open AccessUse superb microvascular imaging to diagnose and predict metastatic cervical lymph nodes in patients with papillary thyroid carcinoma
Papillary thyroid carcinoma (PTC) with metastatic lymph nodes (LNs) is closely associated with disease recurrence. This study accessed the value of superb microvascular imaging (SMI) in the diagnosis and predi...
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Article
Open AccessTumor biomarkers for diagnosis, prognosis and targeted therapy
Tumor biomarkers, the substances which are produced by tumors or the body’s responses to tumors during tumorigenesis and progression, have been demonstrated to possess critical and encouraging value in screeni...
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Article
Beneficial action of cinnamic acid against ovarian cancer via network pharmacology analysis and the pharmacological activity assessment
Naturally occurring cinnamic acid (CA) shows the beneficial potential in the suppression of ovarian cancer (OC). Currently, the in-depth molecular mechanisms of CA to suppress OC are still undescribed entirely...
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Article
Open AccessDesmoglein 2 and desmocollin 2 depletions promote malignancy through distinct mechanisms in triple-negative and luminal breast cancer
Aberrant expressions of desmoglein 2 (Dsg2) and desmocollin 2(Dsc2), the two most widely distributed desmosomal cadherins, have been found to play various roles in cancer in a context-dependent manner. Their s...
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Article
Open AccessTumor-suppressive miR-4732-3p is sorted into fucosylated exosome by hnRNPK to avoid the inhibition of lung cancer progression
Aberrant fucosylation observed in cancer cells contributes to an augmented release of fucosylated exosomes into the bloodstream, where miRNAs including miR-4732-3p hold promise as potential tumor biomarkers in...
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Article
Open AccessExploring variations in IPC competencies: a cross-sectional study among healthcare professionals in Northwest China
This cross-sectional study investigates infection prevention and control (IPC) competencies among healthcare professionals in northwest China, examining the influence of demographic factors, job titles, educat...
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Article
Open AccessShort-chain fatty acid-producing bacterial strains attenuate experimental ulcerative colitis by promoting M2 macrophage polarization via JAK/STAT3/FOXO3 axis inactivation
Patients with inflammatory bowel disease (IBD), dysbiosis, and immunosuppression who receive fecal microbiota transplantation (FMT) from healthy donors are at an increased risk of develo** bacteremia. This s...
