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    Article

    Comparative study of telmisartan tablets prepared via the wet granulation method and pritor™ prepared using the spray-drying method

    The wet granulation method was successfully used to manufacture amorphous telmisartan tablets (CNU) for comparison with the spray-drying method, used for Pritor™. Drug crystallinity in the tablet was character...

    Junsung Park, Hee Jun Park, Wonkyung Cho, Kwang-Ho Cha in Archives of Pharmacal Research (2011)

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    Article

    pH-independent sustained release matrix tablet containing doxazosin mesylate: Effect of citric acid

    The aim of this study was to develop a pH-independent sustained release matrix tablets of doxazosin mesylate. The matrix tablets were prepared by direct compression technique using polyethylene oxide, sodium a...

    Kwang-Ho Cha, Thanh-Huyen Tran, Min-Soo Kim in Archives of Pharmacal Research (2010)

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    Article

    Design of pH-independent extended release matrix tablets of minocycline hydrochloride for the treatment of dementia

    The aim of this study was to develop a pH-independent extended release matrix tablet of minocycline HCl for the treatment of dementia. The matrix tablets were prepared by wet granulation technique using Eudrag...

    Kwang-Ho Cha, Junsung Park, Wonkyung Cho, Dong-Geon Gu in Archives of Pharmacal Research (2009)

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    Article

    Phenethyl isothiocyanate induced apoptosis via down regulation of Bcl-2/XIAP and triggering of the mitochondrial pathway in MCF-7 cells

    Although isothiocyanates have been shown to inhibit carcinogen-induced tumorigenesis, no studies have been made to determine their therapeutic potential for the treatment of breast cancer. In the present study...

    Ji Won Lee, Min Kyung Cho in Archives of Pharmacal Research (2008)