16 Result(s)
within
**kyung Cho
Life Sciences
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Article
Widespread 8-oxoguanine modifications of miRNA seeds differentially regulate redox-dependent cancer development
Oxidative stress contributes to tumourigenesis by altering gene expression. One accompanying modification, 8-oxoguanine (o8G) can change RNA–RNA interactions via o8G•A base pairing, but its regulatory roles remai...
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Biosynthesis and applications of iron oxide nanocomposites synthesized by recombinant Escherichia coli
Recombinant Escherichia coli (E. coli) strain that produces phytochelatin (PC) and/or metallothionein (MT) can synthesize various metal nanoparticles (NPs) by reducing metal ions. Here we report in vivo biosynthe...
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Protective effect of Acer palmatum Thunb. leaf extract on mice with steroid-induced ocular hypertension
Ocular hypertension is a major risk factor for glaucoma, which is characterized by the presence of ganglion cells, ganglion disease, and an irreversible reduction in the number of ganglion cells and axons. Alt...
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Open AccessIntramembrane proteolysis of an extracellular serine protease, epithin/PRSS14, enables its intracellular nuclear function
Epithin/PRSS14, a type II transmembrane serine protease, is an emerging target of cancer therapy because of its critical roles in tumor progression and metastasis. In many circumstances, the protease, through ...
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Article
Coptidis Rhizoma extract inhibits replication of respiratory syncytial virus in vitro and in vivo by inducing antiviral state
Coptidis Rhizoma is derived from the dried rhizome of Ranunculaceous plants and is a commonly used traditional Chinese medicine. Although Coptidis Rhizoma is commonly used for its...
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Identification of Pseudomonas syringae pv. syringae causing bacterial leaf blight of Miscanthus sinensis
In the late summer of 2015, severe leaf blight occurred on Miscanthus sinensis grown on natural riverside lands of the Han River in Seoul, South Korea. Symptoms included chlorosis and necrotic lesions on the leav...
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First report of Pseudomonas syringae pv. syringae causing bacterial leaf blight on Miscanthus × giganteus
In October 2015, a bacterial leaf blight was observed on Miscanthus × giganteus in **ju, South Korea. Symptoms included chlorosis and necrotic lesions on the leaves. Bacteria belonging to the γ-proteobacteria ge...
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Predisposing roles of paraoxonase-1 genetic variants in Korean ischemic stroke patients
Paraoxonase-1 (PON1), a high-density lipoprotein (HDL)-associated enzyme, is involved in the metabolism and detoxification of insecticides and pesticides. The aims of this study were to evaluate the role of PON1
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The forkhead-associated domain 2 (FHA2) in Arabidopsis plays a role in plant fertility by regulating stamen development
The forkhead-associated (FHA) domain is involved in protein–protein interaction by recognizing a phosphothreonine epitope on target proteins. In this study, we investigated in planta functions of the Arabidopsis ...
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PRBP plays a role in plastid ribosomal RNA maturation and chloroplast biogenesis in Nicotiana benthamiana
In the present study, we investigated protein characteristics and physiological functions of PRBP (plastid RNA-binding protein) in Nicotiana benthamiana. PRBP fused to green fluorescent protein (GFP) localized to...
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Association of the vascular endothelial growth factor (VEGF-1154G>A) polymorphism in patients with colorectal cancer
Angiogenesis plays a pivotal role in the development of colon cancer during the promotion and metastasis of tumor growth. Vascular endothelial growth factor (VEGF) is known to be a potent angiogenic factor. Th...
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Association of theXRCC1 gene polymorphisms in patients with stomach cancer
Genetic instability resulting from mutations in repair genes or denaturation in DNA synthesis has been reported to play an important role in the development of cancer. Through studies of single nucleotide poly...
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A nuclear-localized HSP70 confers thermoprotective activity and drought-stress tolerance on plants
To investigate the function of nuclear-localized plant HSP70, we used NtHSP70-1 isolated from Nicotiana tabacum. The subcellular localization of NtHSP70-1 was identified by fluorescence microscopy for NtHSP70-1/G...
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Over-expression of tobacco NtHSP70-1 contributes to drought-stress tolerance in plants
HSP70, a heat shock protein, is a molecular chaperone responsive to various environmental stresses. Here, NtHSP70-1 (AY372069) was a drought-/ABA-inducible gene. We monitored the expression of CaERD15 (early resp...
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Molecular cloning and expression pattern analyses of heat shock protein 70 genes fromNicotiana tabacum
We have isolated three genomic clones that code tobacco HSP70s, using a tobacco hsp70 cDNA clone as a probe.NtHSP70-1, NtHSP70-2, andNtHSP7Q-3 contain full open reading frames of 653, 653, and 648 amino acid resi...
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Identification of genes enhanced by protein-calorie malnutrition by differential display polymerase chain reaction (expression of fibrinogen B β chain, B cell translocation gene 1 and thyroid hormone responsive protein genes)
Protein-calorie malnutrition (PCM), as one of global health problems, arises during protein and/or energy deficit due to disease and nutritional inadequacy. Previously, we showed that PCM elicited oxidative st...
