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Treatment with an immature dendritic cell-targeting vaccine supplemented with IFN-α and an inhibitor of DNA methylation markedly enhances survival in a murine melanoma model

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  1. Article

    Open Access

    Macrophages in cardiovascular diseases: molecular mechanisms and therapeutic targets

    The immune response holds a pivotal role in cardiovascular disease development. As multifunctional cells of the innate immune system, macrophages play an essential role in initial inflammatory response that oc...

    Runkai Chen, Hongrui Zhang, Botao Tang in Signal Transduction and Targeted Therapy (2024)

  2. Article

    Open Access

    Cancer-associated fibroblast-derived extracellular vesicles promote lymph node metastases in oral cavity squamous cell carcinoma by encapsulating ITGB1 and BMI1

    Extracellular vesicles (EVs) have been revealed to facilitate the development of oral squamous cavity cell carcinoma (OCSCC), while its supporting role in lymph node metastases is under continuous investigatio...

    Tianzhu Lv, Hong**g Liu, Ling Mao, Yanrong Song, Lili Liao, Kun Zhong in BMC Cancer (2024)

  3. Article

    Open Access

    Value of high frame rate contrast enhanced ultrasound in gallbladder wall thickening in non-acute setting

    Ultrasound (US) has been widely used in screening and differential diagnosis of gallbladder wall thickening (GWT). However, the sensitivity and specificity for diagnosing wall-thickening type gallbladder cance...

    Lianhua Zhu, Nan Li, Yaqiong Zhu, Peng Han, Bo Jiang, Miao Li, Yukun Luo in Cancer Imaging (2024)

  4. Article

    Open Access

    Inter-observer variation in two-dimensional and three-dimensional ultrasound measurement of papillary thyroid microcarcinoma

    The reliable ultrasound (US) measurements of papillary thyroid microcarcinoma (PTMC) are very important during active surveillance. This prospective study was design to investigate the inter-observer reliabili...

    Lin Yan, Ling Ren, Yingying Li, Yukun Luo in Cancer Imaging (2023)

  5. Article

    Open Access

    MEN1 silencing aggravates tumorigenic potential of AR-independent prostate cancer cells through nuclear translocation and activation of JunD and β-catenin

    Recent studies highlighted the increased frequency of AR-low or -negative prostate cancers (PCas) and the importance of AR-independent mechanisms in driving metastatic castration-resistant PCa (mCRPC) developm...

    Yakun Luo, Virginie Vlaeminck-Guillem in Journal of Experimental & Clinical Cancer … (2021)

  6. Article

    Open Access

    Ultrasound-guided implantation of radioactive 125I seed in radioiodine refractory differentiated thyroid carcinoma

    Treatment for radioiodine refractory differentiated thyroid carcinoma (RR-DTC) is challenging. The purpose of this study was to assess the efficacy and safety of ultrasound-guided implantation of radioactive 125I...

    Wei Chen, Yu kun Luo, Ying Zhang, Qing Song, Jie Tang in BMC Cancer (2021)

  7. Article

    Open Access

    Contrast-enhanced ultrasound in detecting wall invasion and differentiating bland from tumor thrombus during robot-assisted inferior vena cava thrombectomy for renal cell carcinoma

    Vena cava thrombus is one of the main clinical manifestations of locally aggressive renal cell carcinoma (RCC). Inferior vena cava (IVC) wall invasion and presence of bland thrombus could affect the surgical o...

    Qiu-Yang Li, Nan Li, Qing-Bo Huang, Yu-Kun Luo, Bao-Jun Wang, Ai-Tao Guo in Cancer Imaging (2019)

  8. Article

    Open Access

    Patient satisfaction of radiofrequency ablation for symptomatic benign solid thyroid nodules: our experience for 2-year follow up

    The patient satisfaction of symptoms improvement and disease factors that may affect long-term treatment efficacy of radiofrequency ablation (RFA) for non-functioning solid benign thyroid nodules (TNs) over a ...

    Yang Guang, Wen He, Yukun Luo, Hongxia Zhang, Yukang Zhang, Bin Ning in BMC Cancer (2019)

  9. Article

    Open Access

    Prognostic value of CD44 expression in patients with hepatocellular carcinoma: meta-analysis

    CD44 has been reported to be involved with tumor growth and metastasis and has also been implicated as a CSC marker in hepatocellular carcinoma (HCC). However, the prognostic value of CD44 still remains contro...

    Yangkun Luo, Yan Tan in Cancer Cell International (2016)

  10. Article

    Open Access

    Identification and validation of PROM1 and CRTC2 mutations in lung cancer patients

    Genetic alterations could be responsible lung cancer, the leading cause of worldwide cancer death.

    Yanqi He, Yalun Li, Zhixin Qiu, Bin Zhou, Shaoqin Shi, Kui Zhang in Molecular Cancer (2014)