-
Chapter and Conference Paper
A GIS Based Virtual Urban Simulation Environment
This paper presents the development of a virtual reality urban planning tool based on GIS and Virtual Environments to facilitate scenario generation and collaborative urban design. Our system provides an open ...
-
Chapter and Conference Paper
On the Prevention of Invalid Route Injection Attack
In recent years, the Internet is suffering from severe attacks from the global routing system, such as prefix hijack, digital cannon. These attacks break down network services and sabotage infrastructures. In ...
-
Article
Open AccessStool fatty acid soaps, stool consistency and gastrointestinal tolerance in term infants fed infant formulas containing high sn-2 palmitate with or without oligofructose: a double-blind, randomized clinical trial
Formula-fed (FF) infants often have harder stools and higher stool concentrations of fatty acid soaps compared to breastfed infants. Feeding high sn-2 palmitate or the prebiotic oligofructose (OF) may soften stoo...
-
Article
Erratum to: Maternal exposure to fine particulate matter (PM2.5) and pregnancy outcomes: a meta-analysis
-
Article
Open AccessSmoking behaviors before and after implementation of a smoke-free legislation in Guangzhou, China
According to the partial smoke-free legislation implemented on 1 September 2010 in Guangzhou, China, smoke-free did not cover all indoor areas. Some places have a full smoking ban (100 % smoke-free), other pla...
-
Article
Open AccessMetro system in Guangzhou as a hazardous reservoir of methicillin-resistant Staphylococci: findings from a point-prevalence molecular epidemiologic study
Staphylococci are common causes of healthcare-associated and community-associated infections. However, limited data are available on the prevalence, phenotypes and molecular characteristics of Staphylococci in me...
-
Article
Open AccessLivestock-associated methicillin and multidrug resistant S. aureus in humans is associated with occupational pig contact, not pet contact
This study aimed to explore the association of livestock-associated S. aureus with occupational pig contact and pet contact. In this cross-sectional study, 1,422 participants (including 244 pig workers, 200 pet-o...
-
Article
Open AccessUnexpected Reaction Pathway for butyrylcholinesterase-catalyzed inactivation of “hunger hormone” ghrelin
Extensive computational modeling and simulations have been carried out, in the present study, to uncover the fundamental reaction pathway for butyrylcholinesterase (BChE)-catalyzed hydrolysis of ghrelin, demon...
-
Article
Open AccessRole of Histidine 547 of Human Dopamine Transporter in Molecular Interaction with HIV-1 Tat and Dopamine Uptake
HIV-1 Tat plays an important role in HIV-associated neurocognitive disorders (HAND) by disrupting neurotransmission including dopamine uptake by human dopamine transporter (hDAT). Previous studies have demonst...
-
Article
Open AccessBioTriangle: a web-accessible platform for generating various molecular representations for chemicals, proteins, DNAs/RNAs and their interactions
More and more evidences from network biology indicate that most cellular components exert their functions through interactions with other cellular components, such as proteins, DNAs, RNAs and small molecules. ...
-
Article
Open AccessExperimental study and isolation mechanism analysis on emulsion wax curing agent used on cement-stabilized granular base
Based on the analysis in the mechanism of emulsion wax curing agent (EWCA) which was regarded as bond-breaking layer of concrete pavement, tests for shear stress, penetration test, pendulum friction coefficien...
-
Article
Open AccessInfant feeding and health-related quality of life in healthy Chinese infants: results from a prospective, observational cohort study
Infant feeding regimens, including breastfeeding, formula-feeding, or a combination of the two, may influence infant health-related quality of life (HRQOL). However, few studies have examined this association.
-
Article
Open AccessChemSAR: an online pipelining platform for molecular SAR modeling
In recent years, predictive models based on machine learning techniques have proven to be feasible and effective in drug discovery. However, to develop such a model, researchers usually have to combine multipl...
-
Article
Open AccessChromosome structural variation of two cultivated tetraploid cottons and their ancestral diploid species based on a new high-density genetic map
A high-resolution genetic map is a useful tool for assaying genomic structural variation and clarifying the evolution of polyploid cotton. A total of 36956 SSRs, including 11289 released in previous studies an...
-
Article
Open AccessControlled Synthesis of BaYF5:Er3+, Yb3+ with Different Morphology for the Enhancement of Upconversion Luminescence
In this work, Er3+/Yb3+-codoped BaYF5 with different sizes and shapes have been synthesized by a simple solvothermal method. By changing the fluoride source, pH value, solvent, surfactants, Yb3+ concentration, te...
-
Article
Open AccessPyBioMed: a python library for various molecular representations of chemicals, proteins and DNAs and their interactions
With the increasing development of biotechnology and informatics technology, publicly available data in chemistry and biology are undergoing explosive growth. Such wealthy information in these data needs to b...
-
Article
Open AccessQM/MM free energy Simulations of an efficient Gluten Hydrolase (Kuma030) Implicate for a Reactant-State Based Protein-Design Strategy for General Acid/Base Catalysis
It is a grand attraction for contemporary biochemists to computationally design enzymes for novel chemical transformation or improved catalytic efficiency. Rosetta by Baker et al. is no doubt the leading software...
-
Article
Open AccessThe efficacy and safety of Jiedu Tongluo granules for treating post-stroke depression with qi deficiency and blood stasis syndrome: study protocol for a randomized controlled trial
Post-stroke depression (PSD) is the most common psychiatric complication after a stroke. The most frequently used antidepressants are selective serotonin receptor inhibitors (SSRIs) and serotonin and norepinep...
-
Article
Open AccessADMETlab: a platform for systematic ADMET evaluation based on a comprehensively collected ADMET database
Current pharmaceutical research and development (R&D) is a high-risk investment which is usually faced with some unexpected even disastrous failures in different stages of drug discovery. One main reason for R...
-
Article
Open AccessLupus nephritis pathology prediction with clinical indices
Effective treatment of lupus nephritis and assessment of patient prognosis depend on accurate pathological classification and careful use of acute and chronic pathological indices. Renal biopsy can provide mos...
